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Biological importance of imidazole nucleus in the new millennium

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Abstract

Imidazole nucleus is a constituent of many bioactive heterocyclic compounds that are of wide interest because of their diverse biological and clinical applications. This created interest in researchers to synthesize variety of imidazole derivatives and to screen them for their various biological activities viz. anti-cancer, anti-viral, antiHIV, anti-protozoal, anti-mycobacterial, anti-inflammatory, analgesic, anxiolytic, as well anti-diabetic activities.

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  1. Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, 124001, India

    Balasubramanian Narasimhan & Pradeep Kumar

  2. University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, 160014, India

    Deepika Sharma

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  1. Balasubramanian Narasimhan
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  2. Deepika Sharma
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Correspondence to Balasubramanian Narasimhan.

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Narasimhan, B., Sharma, D. & Kumar, P. Biological importance of imidazole nucleus in the new millennium. Med Chem Res 20, 1119–1140 (2011). https://doi.org/10.1007/s00044-010-9472-5

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