Skip to main content
SpringerLink
Log in

Gamma-band power elevation of prefrontal local field potential after posterior dorsal hippocampus–prefrontal long-term potentiation induction in anesthetized rats

  • Research Article
  • Published:
Experimental Brain Research Aims and scope Submit manuscript

Abstract

Previously, we reported an elevation in the power of the medial prefrontal cortex (PFC) local field potential spontaneous gamma-band (40–100 Hz) after long-term depression (LTD) but not long-term potentiation (LTP) in the rat ventral hippocampus CA1 (vCA1)–PFC pathway. In the present study, we analyzed the PFC local field potential before and after the induction of posterior dorsal hippocampus CA1 (pdCA1)–PFC LTP/LTD in vivo. In contrast with vCA1-PFC, the present study found that gamma-band power elevation was associated with pdCA1–PFC LTP but not LTD, although we observed a correlation between LTD and the gamma-band power change. The differences between vCA1– and pdCA1–PFC pathways might be related to differences in synaptic plasticity and behavioral functions. Since the neural connection of the hippocampus and PFC is believed to be involved in the function of the working memory, sustained gamma-band power elevation in the PFC might be related to this function.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  • Amit DJ (1995) The Hebbian paradigm reintegrated: local reverberations as internal representation. Behav Brain Sci 18:617–626

    Article  Google Scholar 

  • Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31–39

    Article  PubMed  CAS  Google Scholar 

  • Bragin A, Jando G, Nadasdy Z, Heteke J, Wise K, Buzsaki G (1995) Gamma (40–100 Hz) oscillation in the hippocampus of the behaving rat. J Neurosci 15:47–60

    PubMed  CAS  Google Scholar 

  • Burette F, Jay TM, Laroche S (2000) Synaptic depression of the hippocampal to prefrontal cortex pathway during a spatial working memory task. Curr Psychol Lett 1:9–23

    Google Scholar 

  • Chrobak JJ, Buzsaki G (1998) Gamma oscillations in the entorhinal cortex of the freely moving rat. J Neurosci 18:388–398

    PubMed  CAS  Google Scholar 

  • Conde F, Marie-Lepoivre E, Audinat E, Crepel F (1995) Afferent connection of the medial frontal cortex of the rat. Cortical and subcortical afferents. J Comp Neurol 352:567–593

    Article  PubMed  CAS  Google Scholar 

  • Doyere V, Burette F, Negro CR, Laroche S (1993) Long-term potentiation of hippocampal afferents and efferents to prefrontal cortex: implications for associative learning. Neuropsychologia 31:1031–1053

    Article  PubMed  CAS  Google Scholar 

  • Ferino F, Thierry AM, Glowinski J (1987) Anatomical and electrophysiological evidence for direct projection from Ammon’s horn to the medial prefrontal cortex in the rat. Exp Brain Res 65:421–426

    Article  PubMed  CAS  Google Scholar 

  • Floresco SB, Seamans JK, Phillips AG (1997) Selective roles for hippocampal, prefrontal cortical, and ventral striatal circuits in radial-arm maze tasks with or without delay. J Neurosci 17:1880–1890

    PubMed  CAS  Google Scholar 

  • Frankland PW, Bontempi B (2005) The organization of recent and remote memories. Nat Rev Neurosci 6:119–130

    Article  PubMed  CAS  Google Scholar 

  • Funahashi S, Kubota K (1994) Working memory and prefrontal cortex. Neurosci Res 21:1–11

    Article  PubMed  CAS  Google Scholar 

  • Gray CM, Singer W (1989) Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex. Proc Natl Acad Sci USA 86:1698–1702

    Article  PubMed  CAS  Google Scholar 

  • Ito M (1989) Long-term depression. Annu Rev Neurosci 12:85–102

    Article  PubMed  CAS  Google Scholar 

  • Izaki Y, Hori K, Nomura M (2000) Disturbance of rat lever-press learning by hippocampal–prefrontal disconnection. Brain Res 860:199–202

    Article  PubMed  CAS  Google Scholar 

  • Izaki Y, Takita M, Jay TM, Kaneko H, Suzuki SS, Nomura M (2001) Effect of long-term potentiation induction on gamma-band electroencephalograms in prefrontal cortex following stimulation of rat hippocampus in vivo. Neurosci Lett 305:57–60

    Article  PubMed  CAS  Google Scholar 

  • Izaki Y, Takita M, Nomura M, Akema T (2002) Effects of hippocampus-induced prefrontal long-term depression on gamma-band local field potential in anesthetized rats. Neurosci Lett 330:204–206

    Article  PubMed  CAS  Google Scholar 

  • Izaki Y, Nomura M, Akema T (2003a) Evoked prefrontal gamma oscillation by hippocampal train stimulation in anesthetized rats. Neurosci Lett 343:53–56

    Article  PubMed  CAS  Google Scholar 

  • Izaki Y, Takita M, Nomura M, Akema T (2003b) Differences between paired-pulse facilitation and long-term potentiation in the dorsal and ventral hippocampal CA1-prefrontal pathways of rats. Brain Res 992:142–145

    Article  PubMed  CAS  Google Scholar 

  • Izaki Y, Takita M, Nomura M, Akema T (2004) Effects of ventral hippocampal long-term potentiation and depression on the gamma-band local field potential in anesthetized rats. Exp Brain Res 157:147–151

    Article  PubMed  Google Scholar 

  • Jay TM, Glowinski J, Thierry AM (1989) Selectivity of the hippocampal projection to the prelimbic area of the prefrontal cortex in the rat. Brain Res 505:337–340

    Article  PubMed  CAS  Google Scholar 

  • Kawashima H, Izaki Y, Grace AA, Takita M (2006) Cooperativity between hippocampal-prefrontal short-term plasticity through associative long-term potentiation. Brain Res 1109:37–44

    Article  PubMed  CAS  Google Scholar 

  • Laroche S, Jay TM, Thierry AM (1990) Long-term potentiation in the prefrontal cortex following stimulation of the hippocampal CA1/subicular region. Neurosci Lett 114:184–190

    Article  PubMed  CAS  Google Scholar 

  • Laroche S, Davis S, Jay TM (2000) Plasticity at hippocampal to prefrontal cortex synapses: dual roles in working memory and consolidation. Hippocampus 10:438–446

    Article  PubMed  CAS  Google Scholar 

  • Maruki K, Izaki Y, Hori K, Nomura M, Yamauchi T (2001a) Effects of rat ventral and dorsal hippocampus temporal inactivation on delayed alternation task. Brain Res 895:273–276

    Article  PubMed  CAS  Google Scholar 

  • Maruki K, Izaki Y, Nomura M, Yamauchi T (2001b) Differences in paired-pulse facilitation and long-term potentiation between dorsal and ventral CA1 regions in anesthetized rats. Hippocampus 11:655–661

    Article  PubMed  CAS  Google Scholar 

  • Moser MB, Moser EI (1998) Functional differentiation in the hippocampus. Hippocampus 8:608–619

    Article  PubMed  CAS  Google Scholar 

  • Mulder AB, Arts MPM, Lopes da Silva FH (1997) Short- and long-term plasticity of the hippocampus to nucleus accumbens and prefrontal cortex pathways in the rat, in vivo. Eur J Neurosci 9:1603–1611

    Article  PubMed  CAS  Google Scholar 

  • Papatheodoropoulos C, Kostopoulos G (2000) Decreased ability of rat temporal hippocampal CA1 region to produce long-term potentiation. Neurosci Lett 279:177–180

    Article  PubMed  CAS  Google Scholar 

  • Paxinos G, Watson G (1986) The rat brain in stereotaxic coordinates. Academic, Sydney

    Google Scholar 

  • Singer W, Gray CM (1995) Visual feature integration and the temporal correlation hypothesis. Annu Rev Neurosci 18:555–586

    Article  PubMed  CAS  Google Scholar 

  • Singer W (2000) Response synchronization: a universal coding strategy for the definition of relations. In: Gazzaniga MS (ed) The new cognitive neurosciences. 2nd edn. MIT Press, Cambridge, pp 325–338

    Google Scholar 

  • Swanson LW (1981) A direct projection from Ammon’s horn to prefrontal cortex in the rat. Brain Res 217:150–154

    Article  PubMed  CAS  Google Scholar 

  • Takita M, Izaki Y, Jay TM, Kaneko H, Suzuki SS (1999) Induction of stable long-term depression in vivo in the hippocampal–prefrontal cortex pathway. Eur J Neurosci 11:4145–4148

    Article  PubMed  CAS  Google Scholar 

  • Tallon-Baudry C, Bertrand O, Peronnet F, Pernier J (1998) Induced gamma-band activity during the delay of a visual short-term memory task in humans. J Neurosci 18:4244–4254

    PubMed  CAS  Google Scholar 

  • Wang G-W, Cai J-X (2006) Disconnection of the hippocampal prefrontal cortical circuits impairs spatial working memory performance in rats. Behav Brain Res 175:329–336

    Article  PubMed  Google Scholar 

  • Womelsdorf T, Fries P, Mitra PP, Desimone R (2006) Gamma-band synchronization in visual cortex predicts speed of change detection. Nature 439:733–736

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, 216-8511, Japan

    Yoshinori Izaki & Tatsuo Akema

Authors
  1. Yoshinori Izaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tatsuo Akema
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yoshinori Izaki.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Izaki, Y., Akema, T. Gamma-band power elevation of prefrontal local field potential after posterior dorsal hippocampus–prefrontal long-term potentiation induction in anesthetized rats. Exp Brain Res 184, 249–253 (2008). https://doi.org/10.1007/s00221-007-1098-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00221-007-1098-6

Keywords

Search

Navigation