Abstract
The degeneration of postural control in the elderly and patients with Parkinson’s disease (PD) can be debilitating and may lead to increased fall risk. This study evaluated the changes in postural control during gait affected by PD and aging using a new method based on the General Tau Theory. Fifteen patients with PD, 11 healthy old adults (HOs), and 15 healthy young adults (HYs) were recruited. Foot trajectories of each participant were monitored during walking by a three-camera Optotrak Certus® motion capture system. The anteroposterior direction of foot movement during stepping was analyzed by tau-G and tau-J guidance strategies. Two linear regression analyses suggested that the tau of the step-gap was strongly coupled onto the tau-J guidance during walking. The regression slope K could estimate the coupling ratio in the tau-coupling equation which reflects the performance of postural control during gait. The mean K value for the PD group, which was highest among the three groups, was approximately 0.5. Therefore, participants in the PD group walked with the poorest postural control and exhibited a relatively hard contact with the endpoint during stepping when compared with those in the HO and HY groups. The HY and HO groups obtained mean K values significantly lower than 0.5, which indicated that the gait was well controlled and ended at low speed with low deceleration. However, the HO group showed a decreased tendency for postural control, in which the mean K value was significantly higher than that of the HY group. The K value was moderately positively correlated with the double support time and negatively correlated with the stride length and walking speed. The tau-J coupling ratio can provide additional insight into gait disturbances and may serve as a reliable, objective, and quantitative tool to evaluate dynamic postural control during walking.
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Acknowledgments
This study was supported by The National Natural Science Foundation of China (Award No. 51275282) and the PhD Programs Foundation of Ministry of Education of China (Award No. 20123108110009). We thank the volunteers for participating in this study. We are grateful to Changlin Yu and Liuyang Wu for their assistance in data collection.
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Zhang, S., Qian, J., Zhang, Z. et al. Age- and Parkinson’s disease-related evaluation of gait by General Tau Theory. Exp Brain Res 234, 2829–2840 (2016). https://doi.org/10.1007/s00221-016-4685-6
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DOI: https://doi.org/10.1007/s00221-016-4685-6