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Zwitterionic phosphorylcholine-protected water-soluble Ag nanoparticles

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Abstract

The water-soluble Ag nanoparticles capped with novel zwitterionic thioalkylated phosphorylcholine were synthesized. The Ag nanoparticles showed remarkable stability in saline media with salt concentrations as high as 2.0 mol/L and plasma using UV-vis absorption spectroscopy. Similarly, compared with tiopronin and citrate-protected Ag nanoparticles, the zwitterionic phosphorylcholine Ag nanoparticles did not precipitate out of solution when charged polyelectrolytes or biopolymers were added. The zwitterionic phosphorylcholine might be a better ligand for stabilizing metal nanoparticles.

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Authors and Affiliations

  1. Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Department of Polymer Science, Zhejiang University, Hangzhou, 310027, China

    Qiao Jin, XiangSheng Liu, JianPing Xu, Jian Ji & JiaCong Shen

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  1. Qiao Jin
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  2. XiangSheng Liu
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  3. JianPing Xu
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  4. Jian Ji
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  5. JiaCong Shen
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Correspondence to Jian Ji.

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Supported by the National Natural Science Foundation of China (Grant Nos. 20774082 and 50703036), National High Technology Research and Development Program of China (Grant Nos. 2006AA03Z329 and 2006AA032444) and Science and Technology Projects of Zhejiang Province (Grant No. 2007C24G2010020)

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Jin, Q., Liu, X., Xu, J. et al. Zwitterionic phosphorylcholine-protected water-soluble Ag nanoparticles. Sci. China Ser. B-Chem. 52, 64–68 (2009). https://doi.org/10.1007/s11426-008-0106-4

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  • DOI: https://doi.org/10.1007/s11426-008-0106-4

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