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Detection of Blood Plasma Concentration Theoretically Using SPR-Based Biosensor Employing Black Phosphor Layers and Different Metals

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Abstract

The main role of blood plasma is to transport proteins, hormones, and nutrients to certain parts of the body. All blood constituents are carried by blood plasma through the circulatory system. Cells get rid of waste products into the plasma. In this paper, we present a surface plasmon resonance (SPR) biosensor based on a black phosphor (BP) layer to improve the sensor performance. The black phosphor layer is employed as an interacting medium with the sensing medium for the improvement of the sensor sensitivity. The sensor is employed for the detection of blood plasma. Four metals are used: silver (Ag), gold (Au), copper (Cu), and aluminum (Al). We found that structures with the BP layer have better performance than those without a BP layer. Cu-structure has shown the highest sensitivity while the Ag-structure has shown the highest quality factor and detection accuracy and the lowest FWHM. As the concentration of the plasma increases, the sensitivity can be enhanced.

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Funding

The authors are thankful to the Deanship of Scientific Research at Najran University for funding this work under the Research Groups Funding program grant code (NU/RG/SERC/11/16).

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Authors and Affiliations

  1. Electrical Engineering Department, College of Engineering, Najran University, Najran, Kingdom of Saudi Arabia

    Abdulkarem H. M. Almawgani & Adam R. H. Alhawari

  2. Physics Department, Islamic University of Gaza, P.O. Box 108, Gaza, Palestine

    Malek G. Daher & Sofyan A. Taya

  3. Al Al-Bayt University, P.O. Box 130040, Mafraq, 25113, Jordan

    Melad M. Olaimat

  4. Department of Electrical and Electronics Engineering, Nisantasi University, Istanbul, Turkey

    Ilhamic Colak

Authors
  1. Abdulkarem H. M. Almawgani
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  2. Malek G. Daher
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  3. Sofyan A. Taya
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  4. Melad M. Olaimat
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  5. Adam R. H. Alhawari
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  6. Ilhamic Colak
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Contributions

All authors contributed to the study conception and design. Mathematical derivation and part of the editing were performed by Abdulkarem H. M. Almawgani and Malek G. Daher. The code and part of the editing were performed by Sofyan A. Taya and Melad M. Olaimat. The first draft of the manuscript was written by Adam R. H. Alhawari and Ilhami Colak. Discussion of the results was performed by Sofyan A Taya. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Sofyan A. Taya.

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Almawgani, A.H.M., Daher, M.G., Taya, S.A. et al. Detection of Blood Plasma Concentration Theoretically Using SPR-Based Biosensor Employing Black Phosphor Layers and Different Metals. Plasmonics 17, 1751–1764 (2022). https://doi.org/10.1007/s11468-022-01662-3

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  • DOI: https://doi.org/10.1007/s11468-022-01662-3

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