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Recent advances in the application of nanomaterials in enzymatic glucose sensors

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Abstract

Due to the critical role of glucose level in the diagnosis and treatment of diabetes, as well as the increasing number of diabetics, there is an overwhelming demand for developing glucose sensors. It is well acknowledged that these sensors, especially those based on glucose oxidase, have played an important role in blood glucose detection. Inspired by the attractive properties, nanomaterials, especially nanostructured carbon and metal/metal oxides, have been extensively explored to develop enzymatic glucose sensors with high sensitivity, fast response time, and satisfied stability. In this review, a brief history of glucose biosensors is firstly presented. Furthermore, we discuss the currently available fabrication possesses in the field of enzymatic glucose biosensors based on nanomaterials, focusing on the carbon-based, metal-based, and metal oxides-based nanocomposites. What is more, we discuss the challenges and attempt to give an outlook on the possible further developments.

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Acknowledgments

This work was supported by grants from Natural Science Foundation of Heilongjiang Province (No. C201319).

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Authors and Affiliations

  1. Department of Basic Medicine, Qiqihar Medical University, Qiqihar, 161006, China

    Yanxin Lv, Yu Wang, Zhiqiang Lun & Chunhui Xia

  2. Department of Orthopeadic Surgery, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, 161001, China

    Song Jin

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  1. Yanxin Lv
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Correspondence to Chunhui Xia.

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Lv, Y., Jin, S., Wang, Y. et al. Recent advances in the application of nanomaterials in enzymatic glucose sensors. J IRAN CHEM SOC 13, 1767–1776 (2016). https://doi.org/10.1007/s13738-016-0894-y

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