Skip to main content

2011 | OriginalPaper | Buchkapitel

Luminescent Chemical Sensing, Biosensing, and Screening Using Upconverting Nanoparticles

verfasst von : Daniela E. Achatz, Reham Ali, Otto S. Wolfbeis

Erschienen in: Luminescence Applied in Sensor Science

Verlag: Springer Berlin Heidelberg

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Upconverting nanoparticles (UCNPs) display the unique property of converting near-infrared light (with wavelengths of typically 800–1,000 nm) into visible luminescence. Following a short introduction into the mechanisms leading to the effect, the main classes of materials used are discussed. We then review the state of the art of using UCNPs: (1) to label biomolecules such as antibodies and (synthetic) oligomers for use in affinity assay and flow assays; (2) to act as nanolamps whose emission intensity is modulated by chemical indicators, thus leading to a novel kind of chemical sensors; and (3), to act as donors in luminescence resonance energy transfer in chemical sensors and biosensors.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Auzel F (2004) Upconversion and anti-Stokes processes with f and d ions in solids. Chem Rev 104:139–173CrossRef Auzel F (2004) Upconversion and anti-Stokes processes with f and d ions in solids. Chem Rev 104:139–173CrossRef
2.
Zurück zum Zitat Suyver JF, Aebischer A, Biner D, Gerner P, Grimm J, Heer S, Krämer KW, Reinhard C, Güdel HU (2005) Novel materials doped with trivalent lanthanides and transition metal ions showing near-infrared to visible photon upconversion. Opt Mater 27:1111–1130CrossRef Suyver JF, Aebischer A, Biner D, Gerner P, Grimm J, Heer S, Krämer KW, Reinhard C, Güdel HU (2005) Novel materials doped with trivalent lanthanides and transition metal ions showing near-infrared to visible photon upconversion. Opt Mater 27:1111–1130CrossRef
3.
Zurück zum Zitat Gamelin DR, Güdel HU (2001) Upconversion processes in transition metal and rare earth metal systems. In: Topics in Current Chemistry, vol 214. Springer, Berlin Gamelin DR, Güdel HU (2001) Upconversion processes in transition metal and rare earth metal systems. In: Topics in Current Chemistry, vol 214. Springer, Berlin
4.
Zurück zum Zitat Joubert MF (1999) Photon avalanche upconversion in rare earth laser materials. Opt Mater 11:181–203CrossRef Joubert MF (1999) Photon avalanche upconversion in rare earth laser materials. Opt Mater 11:181–203CrossRef
5.
Zurück zum Zitat Rapaport A, Milliez J, Bass M, Cassanho A, Jenssen H (2006) Review of the properties of up-conversion phosphors for new emissive displays. J Disp Technol 2:68–79CrossRef Rapaport A, Milliez J, Bass M, Cassanho A, Jenssen H (2006) Review of the properties of up-conversion phosphors for new emissive displays. J Disp Technol 2:68–79CrossRef
6.
Zurück zum Zitat Wang F, Liu X (2009) Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals. Chem Soc Rev 38:976–989CrossRef Wang F, Liu X (2009) Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals. Chem Soc Rev 38:976–989CrossRef
7.
Zurück zum Zitat Wang L, Li Y (2007) Controlled synthesis and luminescence of lanthanide doped NaYF4 nanocrystals. Chem Mater 19:727–734CrossRef Wang L, Li Y (2007) Controlled synthesis and luminescence of lanthanide doped NaYF4 nanocrystals. Chem Mater 19:727–734CrossRef
8.
Zurück zum Zitat Wang X, Zhuang J, Peng Q, Li Y (2005) A general strategy for nanocrystal synthesis. Nature 437:121–124CrossRef Wang X, Zhuang J, Peng Q, Li Y (2005) A general strategy for nanocrystal synthesis. Nature 437:121–124CrossRef
9.
Zurück zum Zitat Liu X, Zhao J, Sun Y, Song K, Yu Y, Du C, Kong X, Zhang H (2009) Ionothermal synthesis of hexagonal phase NaYF4:Yb3+,Er3+/Tm3+ upconversion nanophosphors. Chem Commun 6628–6630 Liu X, Zhao J, Sun Y, Song K, Yu Y, Du C, Kong X, Zhang H (2009) Ionothermal synthesis of hexagonal phase NaYF4:Yb3+,Er3+/Tm3+ upconversion nanophosphors. Chem Commun 6628–6630
10.
Zurück zum Zitat Heer S, Kömpe K, Güdel HU, Haase M (2004) Highly efficient multicolor upconversion emission in transparent colloids of lanthanide-doped NaYF4 nanocrystals. Adv Mater 16:2102–2105CrossRef Heer S, Kömpe K, Güdel HU, Haase M (2004) Highly efficient multicolor upconversion emission in transparent colloids of lanthanide-doped NaYF4 nanocrystals. Adv Mater 16:2102–2105CrossRef
11.
Zurück zum Zitat Zhang H, Li Y, Ivanov IA, Qu Y, Huang Y, Duan X (2010) Plasmonic modulation of the upconversion fluorescence in NaYF4:Yb/Tm hexaplate nanocrystals using gold nanoparticles or nanoshells. Angew Chem Int Ed 49:2865–2868CrossRef Zhang H, Li Y, Ivanov IA, Qu Y, Huang Y, Duan X (2010) Plasmonic modulation of the upconversion fluorescence in NaYF4:Yb/Tm hexaplate nanocrystals using gold nanoparticles or nanoshells. Angew Chem Int Ed 49:2865–2868CrossRef
12.
Zurück zum Zitat Lü Q, Guo FY, Sun L, Li AH, Zhao LC (2008) Silica-/titania-coated Y2O3:Tm3+, Yb3+ nanoparticles with improvement in upconversion luminescence induced by different thickness shells. J Appl Phys 103:123533CrossRef Lü Q, Guo FY, Sun L, Li AH, Zhao LC (2008) Silica-/titania-coated Y2O3:Tm3+, Yb3+ nanoparticles with improvement in upconversion luminescence induced by different thickness shells. J Appl Phys 103:123533CrossRef
13.
Zurück zum Zitat Lü Q, Li A, Guo F, Sun L, Zhao L (2008) Experimental study on the surface modification of Y2O3:Tm3+/Yb3+ nanoparticles to enhance upconversion fluorescence and weaken aggregation. Nanotechnology 19:145701CrossRef Lü Q, Li A, Guo F, Sun L, Zhao L (2008) Experimental study on the surface modification of Y2O3:Tm3+/Yb3+ nanoparticles to enhance upconversion fluorescence and weaken aggregation. Nanotechnology 19:145701CrossRef
14.
Zurück zum Zitat Wang Y, Tu L, Zhao J, Sun Y, Kong X, Zhang H (2009) Upconversion luminescence of β-NaYF4:Yb3+, Er3+@ β-NaYF4 core/shell nanoparticles: excitation power density and surface dependence. J Phys Chem C 113:7164–7169CrossRef Wang Y, Tu L, Zhao J, Sun Y, Kong X, Zhang H (2009) Upconversion luminescence of β-NaYF4:Yb3+, Er3+@ β-NaYF4 core/shell nanoparticles: excitation power density and surface dependence. J Phys Chem C 113:7164–7169CrossRef
15.
Zurück zum Zitat Vetrone F, Boyer JC, Capobianco JA, Speghini A, Bettinelli M (2003) Concentration-dependent near-infrared to visible upconversion in nanocrystalline and bulk Y2O3:Er3+. Chem Mater 15:2737–2743CrossRef Vetrone F, Boyer JC, Capobianco JA, Speghini A, Bettinelli M (2003) Concentration-dependent near-infrared to visible upconversion in nanocrystalline and bulk Y2O3:Er3+. Chem Mater 15:2737–2743CrossRef
16.
Zurück zum Zitat Yi G, Lu H, Zhao S, Ge Y, Yang W, Chen D, Guo LH (2004) Synthesis, characterization, and biological application of size-controlled nanocrystalline NaYF4:Yb, Er infrared-to-visible up-conversion phosphors. Nano Lett 4:2191–2196CrossRef Yi G, Lu H, Zhao S, Ge Y, Yang W, Chen D, Guo LH (2004) Synthesis, characterization, and biological application of size-controlled nanocrystalline NaYF4:Yb, Er infrared-to-visible up-conversion phosphors. Nano Lett 4:2191–2196CrossRef
17.
Zurück zum Zitat Muth O, Brockmann H, Schmidt W, Bailleu A, Brauer G, Paeschke M, Ahlers B, Franz-Burgholz A, Zerbel H (2002) Eur Pat 1.241,021 Muth O, Brockmann H, Schmidt W, Bailleu A, Brauer G, Paeschke M, Ahlers B, Franz-Burgholz A, Zerbel H (2002) Eur Pat 1.241,021
18.
Zurück zum Zitat Kim WJ, Nyk M, Prasad PN (2009) Color-coded multilayer photopatterned microstructures using lanthanide(III) ion co-doped NaYF4 nanoparticles with upconversion luminescence for possible applications in security. Nanotechnology 20:85301–185307CrossRef Kim WJ, Nyk M, Prasad PN (2009) Color-coded multilayer photopatterned microstructures using lanthanide(III) ion co-doped NaYF4 nanoparticles with upconversion luminescence for possible applications in security. Nanotechnology 20:85301–185307CrossRef
19.
Zurück zum Zitat Chatterjee DK, Fong LS, Zhang Y (2008) Nanoparticles in photodynamic therapy: an emerging paradigm. Adv Drug Deliv Rev 60:1627–1637CrossRef Chatterjee DK, Fong LS, Zhang Y (2008) Nanoparticles in photodynamic therapy: an emerging paradigm. Adv Drug Deliv Rev 60:1627–1637CrossRef
20.
Zurück zum Zitat Bechet D, Couleaud P, Frochot C, Viriot ML, Guillemin F, Barberi-Heyob M (2008) Nanoparticles as vehicles for delivery of photodynamic therapy agents. Trends Biotechnol 26:612–621CrossRef Bechet D, Couleaud P, Frochot C, Viriot ML, Guillemin F, Barberi-Heyob M (2008) Nanoparticles as vehicles for delivery of photodynamic therapy agents. Trends Biotechnol 26:612–621CrossRef
21.
Zurück zum Zitat Wang F, Liu X (2008) Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles. J Am Chem Soc 130:5642–5643CrossRef Wang F, Liu X (2008) Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles. J Am Chem Soc 130:5642–5643CrossRef
22.
Zurück zum Zitat Wang M, Mi C, Zhang Y, Liu J, Li F, Mao C, Xu S (2009) NIR-responsive silica-coated NaYF4:Er/Tm/Ho upconversion fluorescent nanoparticles with tunable emission colors and their applications in immunolabeling and fluorescent imaging of cancer cells. J Phys Chem C 113:19021–19027CrossRef Wang M, Mi C, Zhang Y, Liu J, Li F, Mao C, Xu S (2009) NIR-responsive silica-coated NaYF4:Er/Tm/Ho upconversion fluorescent nanoparticles with tunable emission colors and their applications in immunolabeling and fluorescent imaging of cancer cells. J Phys Chem C 113:19021–19027CrossRef
24.
Zurück zum Zitat Chen GY, Liu HC, Somesfalean G, Sheng YQ, Liang HJ, Zhang ZG, Sun Q, Wang FP (2008) Enhancement of the upconversion radiation in Y2O3:Er3+ nanocrystals by codoping with Li+ ions. Appl Phys Lett 92:113114CrossRef Chen GY, Liu HC, Somesfalean G, Sheng YQ, Liang HJ, Zhang ZG, Sun Q, Wang FP (2008) Enhancement of the upconversion radiation in Y2O3:Er3+ nanocrystals by codoping with Li+ ions. Appl Phys Lett 92:113114CrossRef
25.
Zurück zum Zitat Yi GS, Chow GM (2007) Water-soluble NaYF4:Yb, Er(Tm)/NaYF4/polymer core/shell/shell nanoparticles with significant enhancement of upconversion fluorescence. Chem Mater 19:341–343CrossRef Yi GS, Chow GM (2007) Water-soluble NaYF4:Yb, Er(Tm)/NaYF4/polymer core/shell/shell nanoparticles with significant enhancement of upconversion fluorescence. Chem Mater 19:341–343CrossRef
26.
Zurück zum Zitat Zijlmans HJMAA, Bonnet J, Burton J, Kardos K, Vail T, Niedbala RS, Tanke HJ (1999) Detection of cell and tissue surface antigens using up-converting phosphors: a new reporter technology. Anal Biochem 267:30–36CrossRef Zijlmans HJMAA, Bonnet J, Burton J, Kardos K, Vail T, Niedbala RS, Tanke HJ (1999) Detection of cell and tissue surface antigens using up-converting phosphors: a new reporter technology. Anal Biochem 267:30–36CrossRef
27.
Zurück zum Zitat Zarling DA, Rossi MJ, Peppers NA, Kane J, Faris GW, Dyer MJ (1998) Up-converting reporters for biological and other assays using laser excitation techniques. US Patent 5,736,410 Zarling DA, Rossi MJ, Peppers NA, Kane J, Faris GW, Dyer MJ (1998) Up-converting reporters for biological and other assays using laser excitation techniques. US Patent 5,736,410
28.
Zurück zum Zitat van de Rijke F, Zijlmans H, Li S, Vail T, Raap AK, Niedbala RS, Tanke HJ (2001) Up-converting phosphor reporters for nucleic acid microarrays. Nat Biotechnol 19:273–276CrossRef van de Rijke F, Zijlmans H, Li S, Vail T, Raap AK, Niedbala RS, Tanke HJ (2001) Up-converting phosphor reporters for nucleic acid microarrays. Nat Biotechnol 19:273–276CrossRef
29.
Zurück zum Zitat Corstjens PLAM, van Lieshout L, Zuiderwijk M, Kornelis D, Tanke HJ, Deelder AM, van Dam GJ (2008) Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum. J Clin Microbiol 46:171–176CrossRef Corstjens PLAM, van Lieshout L, Zuiderwijk M, Kornelis D, Tanke HJ, Deelder AM, van Dam GJ (2008) Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum. J Clin Microbiol 46:171–176CrossRef
30.
Zurück zum Zitat Malamud D, Bau H, Niedbala S, Corstjens P (2005) Point detection of pathogens in oral samples. Adv Dent Res 18:12–16CrossRef Malamud D, Bau H, Niedbala S, Corstjens P (2005) Point detection of pathogens in oral samples. Adv Dent Res 18:12–16CrossRef
31.
Zurück zum Zitat Zuiderwijk M, Tanke HK, Niedbala RS, Corstjens PLMA (2003) An amplification-free hybridization-based DNA assay to detect Streptococcus pneumoniae utilizing the up-converting phosphor technology. Clin Biochem 36:401–403CrossRef Zuiderwijk M, Tanke HK, Niedbala RS, Corstjens PLMA (2003) An amplification-free hybridization-based DNA assay to detect Streptococcus pneumoniae utilizing the up-converting phosphor technology. Clin Biochem 36:401–403CrossRef
32.
Zurück zum Zitat Corstjens P, Zuiderwijk M, Brink A, Li S, Feindt H, Niedbala RS, Tanke H (2001) Use of up-converting phosphor reporters in lateral-flow assays to detect specific nucleic acid sequences: a rapid, sensitive DNA test to identify human papillomavirus type 16 infection. Clin Chem 47:1885–1893 Corstjens P, Zuiderwijk M, Brink A, Li S, Feindt H, Niedbala RS, Tanke H (2001) Use of up-converting phosphor reporters in lateral-flow assays to detect specific nucleic acid sequences: a rapid, sensitive DNA test to identify human papillomavirus type 16 infection. Clin Chem 47:1885–1893
33.
Zurück zum Zitat Corstjens PLAM, Zuiderwijk M, Nilsson M, Feindt H, Niedbala RS, Tanke HJ (2003) Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay. Anal Biochem 312:191–200CrossRef Corstjens PLAM, Zuiderwijk M, Nilsson M, Feindt H, Niedbala RS, Tanke HJ (2003) Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay. Anal Biochem 312:191–200CrossRef
34.
Zurück zum Zitat Niedbala RS, Feindt H, Kardos K, Vail T, Burton J, Bielska B, Li S, Milunic D, Bourdelle P, Vallejo R (2001) Detection of analytes by immunoassay using up-converting phosphor technolgy. Anal Biochem 293:22–30CrossRef Niedbala RS, Feindt H, Kardos K, Vail T, Burton J, Bielska B, Li S, Milunic D, Bourdelle P, Vallejo R (2001) Detection of analytes by immunoassay using up-converting phosphor technolgy. Anal Biochem 293:22–30CrossRef
35.
Zurück zum Zitat Corstjens PLAM, Zuiderwijk M, Tanke HJ, van der Ploeg-van Schip JJ, Ottenhoff THM, Geluk A (2008) A user-friendly, highly sensitive assay to detect the IFN-γ secretion by T-cells. Clin Biochem 41:440–444CrossRef Corstjens PLAM, Zuiderwijk M, Tanke HJ, van der Ploeg-van Schip JJ, Ottenhoff THM, Geluk A (2008) A user-friendly, highly sensitive assay to detect the IFN-γ secretion by T-cells. Clin Biochem 41:440–444CrossRef
36.
Zurück zum Zitat Corstjens PLAM, Chen Z, Zuiderwijk M, Bau HH, Abrams WR, Malamud D, Niedbala RS, Tanke HJ (2007) Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV and TB). Ann NY Acad Sci 1098:437–445CrossRef Corstjens PLAM, Chen Z, Zuiderwijk M, Bau HH, Abrams WR, Malamud D, Niedbala RS, Tanke HJ (2007) Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV and TB). Ann NY Acad Sci 1098:437–445CrossRef
37.
Zurück zum Zitat Corstjens PLAM, Li S, Zuiderwijk M, Kardos K, Abrams WR, Niedbala RS, Tanke HJ (2005) Infrared up-converting phosphors for bioassays. IEE Proc Nanobiotechnol 152:64–72CrossRef Corstjens PLAM, Li S, Zuiderwijk M, Kardos K, Abrams WR, Niedbala RS, Tanke HJ (2005) Infrared up-converting phosphors for bioassays. IEE Proc Nanobiotechnol 152:64–72CrossRef
38.
Zurück zum Zitat Hampl J, Hall M, Mufti NA, Yao YMM, MacQueen DB, Wright WH, Cooper DE (2002) Upconverting phosphor reporters in immunochromatographic assays. Anal Biochem 288:176–187CrossRef Hampl J, Hall M, Mufti NA, Yao YMM, MacQueen DB, Wright WH, Cooper DE (2002) Upconverting phosphor reporters in immunochromatographic assays. Anal Biochem 288:176–187CrossRef
39.
Zurück zum Zitat Li L, Zhou L, Yu Y, Zhu Z, Lin C, Lu C, Yang R (2009) Development of up-converting phosphor technology-based lateral-flow assay for rapidly quantitative detection of hepatitis B surface antibody. Diagn Microbiol Infect Dis 63:165–172CrossRef Li L, Zhou L, Yu Y, Zhu Z, Lin C, Lu C, Yang R (2009) Development of up-converting phosphor technology-based lateral-flow assay for rapidly quantitative detection of hepatitis B surface antibody. Diagn Microbiol Infect Dis 63:165–172CrossRef
40.
Zurück zum Zitat Mokkapati VK, Niedbala RS, Kardos K, Perez RJ, Guo M, Tanke HJ, Corstjens PLAM (2007) Evaluation of Uplink RSV: prototype rapid antigen test for detection of respiratory syncytial virus infection. Ann NY Acad Sci 1098:476–485CrossRef Mokkapati VK, Niedbala RS, Kardos K, Perez RJ, Guo M, Tanke HJ, Corstjens PLAM (2007) Evaluation of Uplink RSV: prototype rapid antigen test for detection of respiratory syncytial virus infection. Ann NY Acad Sci 1098:476–485CrossRef
41.
Zurück zum Zitat Steinmeyer S, Polzius R, Manns A (2005) Dräger drug test: test for illegal drugs in oral-fluid samples. In: Wong RC, Tse HY (eds) Drugs of abuse. Humana Press Inc, Totowa, New Jersey Steinmeyer S, Polzius R, Manns A (2005) Dräger drug test: test for illegal drugs in oral-fluid samples. In: Wong RC, Tse HY (eds) Drugs of abuse. Humana Press Inc, Totowa, New Jersey
42.
Zurück zum Zitat Wright WH, Rundle G, Mufti NA, Yao YMM, Carlisle CB, Cooper DE (2007) Upconverting phosphors for detection and identification using antibodies. In: Van Emon JM (ed) Immunoassays and other bioanalytical techniques. CRC Press, Boca Raton Wright WH, Rundle G, Mufti NA, Yao YMM, Carlisle CB, Cooper DE (2007) Upconverting phosphors for detection and identification using antibodies. In: Van Emon JM (ed) Immunoassays and other bioanalytical techniques. CRC Press, Boca Raton
43.
Zurück zum Zitat Li JJ, Ouellette AL, Giovangrandi L, Cooper DE, Ricco AJ, Kovacs GTA (2008) Optical scanner for immunoassays with up-converting phosphorescent labels. IEEE Trans Biomed Eng 55:1560–1571CrossRef Li JJ, Ouellette AL, Giovangrandi L, Cooper DE, Ricco AJ, Kovacs GTA (2008) Optical scanner for immunoassays with up-converting phosphorescent labels. IEEE Trans Biomed Eng 55:1560–1571CrossRef
44.
Zurück zum Zitat McDonagh C, Burke CS, MacCraith BD (2008) Optical chemical sensors. Chem Rev 108:400–422CrossRef McDonagh C, Burke CS, MacCraith BD (2008) Optical chemical sensors. Chem Rev 108:400–422CrossRef
45.
Zurück zum Zitat Borisov SM, Wolfbeis OS (2008) Optical biosensors. Chem Rev 108:423–461CrossRef Borisov SM, Wolfbeis OS (2008) Optical biosensors. Chem Rev 108:423–461CrossRef
46.
Zurück zum Zitat Thevenot DR, Tóth K, Durst RA, Wilson GS (2001) Electrochemical biosensors: recommended definitions and classification. Biosens Bioelectron 16:121–131CrossRef Thevenot DR, Tóth K, Durst RA, Wilson GS (2001) Electrochemical biosensors: recommended definitions and classification. Biosens Bioelectron 16:121–131CrossRef
47.
Zurück zum Zitat Janata J (2009) Principles of chemical sensors, 2nd edn. Springer, BerlinCrossRef Janata J (2009) Principles of chemical sensors, 2nd edn. Springer, BerlinCrossRef
48.
Zurück zum Zitat Sun L, Peng H, Stich MIJ, Achatz DE, Wolfbeis OS (2009) pH sensor based on upconverting luminescent lanthanide nanorods. Chem Commun 5000–5002 Sun L, Peng H, Stich MIJ, Achatz DE, Wolfbeis OS (2009) pH sensor based on upconverting luminescent lanthanide nanorods. Chem Commun 5000–5002
49.
Zurück zum Zitat Wolfbeis OS, Werner T, Rodriguez NV, Kessler MA (1992) LED-compatible fluorosensor for measurement of near-neutral pH values. Mikrochim Acta 108:133–141CrossRef Wolfbeis OS, Werner T, Rodriguez NV, Kessler MA (1992) LED-compatible fluorosensor for measurement of near-neutral pH values. Mikrochim Acta 108:133–141CrossRef
50.
Zurück zum Zitat Wolfbeis OS, Leiner M (1985) Mapping of the total fluorescence of human blood serum as a new method for its characterization. Anal Chim Acta 167:203–215CrossRef Wolfbeis OS, Leiner M (1985) Mapping of the total fluorescence of human blood serum as a new method for its characterization. Anal Chim Acta 167:203–215CrossRef
51.
Zurück zum Zitat Ali R, Saleh SM, Meier RJ, Azab HA, Elgawad I, Wolfbeis OS (2010) Upconverting Nanoparticle Based Optical Sensor for Carbon Dioxide. Sens Actuators B Chem 150:126–131 Ali R, Saleh SM, Meier RJ, Azab HA, Elgawad I, Wolfbeis OS (2010) Upconverting Nanoparticle Based Optical Sensor for Carbon Dioxide. Sens Actuators B Chem 150:126–131
52.
Zurück zum Zitat Mader HS, Wolfbeis OS (2010) Optical ammonia sensor based on upconverting luminescent nanoparticles. Anal Chem 82:5002–5004CrossRef Mader HS, Wolfbeis OS (2010) Optical ammonia sensor based on upconverting luminescent nanoparticles. Anal Chem 82:5002–5004CrossRef
53.
Zurück zum Zitat Wang XD, Chen HX, Zhao Y, Chen X (2010) Optical oxygen sensors move towards colorimetric determination. Trends Anal Chem 29:319–338CrossRef Wang XD, Chen HX, Zhao Y, Chen X (2010) Optical oxygen sensors move towards colorimetric determination. Trends Anal Chem 29:319–338CrossRef
54.
Zurück zum Zitat Trettnak W, Wolfbeis OS (1990) Fiber optic cholesterol biosensor with an oxygen optrode as the transducer. Anal Biochem 184:124–127CrossRef Trettnak W, Wolfbeis OS (1990) Fiber optic cholesterol biosensor with an oxygen optrode as the transducer. Anal Biochem 184:124–127CrossRef
55.
Zurück zum Zitat Weigl BH, Holobar A, Trettnak W, Klimant I, Kraus H, O'Leary P, Wolfbeis OS (1994) Optical triple sensor for measuring pH oxygen and carbon dioxide. J Biotechnol 32:127–138CrossRef Weigl BH, Holobar A, Trettnak W, Klimant I, Kraus H, O'Leary P, Wolfbeis OS (1994) Optical triple sensor for measuring pH oxygen and carbon dioxide. J Biotechnol 32:127–138CrossRef
56.
Zurück zum Zitat Borisov SM, Klimant I (2007) Ultrabright oxygen optodes based on cyclometalated iridium(III) coumarin complexes. Anal Chem 79:7501–7509CrossRef Borisov SM, Klimant I (2007) Ultrabright oxygen optodes based on cyclometalated iridium(III) coumarin complexes. Anal Chem 79:7501–7509CrossRef
57.
Zurück zum Zitat Zhang P, Rogelj S, Nguyen K, Wheeler D (2006) Design of a highly sensitive and specific nucleotide sensor based on photon upconverting particles. J Am Chem Soc 128:12410–12411CrossRef Zhang P, Rogelj S, Nguyen K, Wheeler D (2006) Design of a highly sensitive and specific nucleotide sensor based on photon upconverting particles. J Am Chem Soc 128:12410–12411CrossRef
58.
Zurück zum Zitat Kumar M, Guo Y, Zhang P (2009) Highly sensitive and selective oligonucleotide sensor for sickle cell disease gene using photon upconverting nanoparticles. Biosens Bioelectron 24:1522–1526CrossRef Kumar M, Guo Y, Zhang P (2009) Highly sensitive and selective oligonucleotide sensor for sickle cell disease gene using photon upconverting nanoparticles. Biosens Bioelectron 24:1522–1526CrossRef
59.
Zurück zum Zitat Kumar M, Zhang P (2009) Highly sensitive and selective label-free optical detection of DNA hybridization based on photon upconverting nanoparticles. Langmuir 25:6024–6027CrossRef Kumar M, Zhang P (2009) Highly sensitive and selective label-free optical detection of DNA hybridization based on photon upconverting nanoparticles. Langmuir 25:6024–6027CrossRef
60.
Zurück zum Zitat Rantanen T, Järvenpää ML, Vuojola J, Arppe R, Kuningas K, Soukka T (2009) Upconverting phosphors in a dual-parameter LRET-based hybridization assay. Analyst 134:1713–1716CrossRef Rantanen T, Järvenpää ML, Vuojola J, Arppe R, Kuningas K, Soukka T (2009) Upconverting phosphors in a dual-parameter LRET-based hybridization assay. Analyst 134:1713–1716CrossRef
61.
Zurück zum Zitat Wang M, Hou W, Mi CC, Wang WX, Xu ZR, Teng HH, Mao CB, Xu SK (2009) Immunoassay of goat antihuman immunoglobulin G antibody based on luminescence resonance energy transfer between near-infrared responsive NaYF4:Yb, Er upconversion fluorescent nanoparticles and gold nanoparticles. Anal Chem 81:8783–8789CrossRef Wang M, Hou W, Mi CC, Wang WX, Xu ZR, Teng HH, Mao CB, Xu SK (2009) Immunoassay of goat antihuman immunoglobulin G antibody based on luminescence resonance energy transfer between near-infrared responsive NaYF4:Yb, Er upconversion fluorescent nanoparticles and gold nanoparticles. Anal Chem 81:8783–8789CrossRef
62.
Zurück zum Zitat Wang L, Yan R, Huo Z, Wang L, Zeng J, Bao J, Wang X, Peng Q, Li Y (2005) Fluorescence resonance energy transfer biosensor based on upconversion-luminescent nanoparticles. Angew Chem Int Ed Engl 117:6208–6211CrossRef Wang L, Yan R, Huo Z, Wang L, Zeng J, Bao J, Wang X, Peng Q, Li Y (2005) Fluorescence resonance energy transfer biosensor based on upconversion-luminescent nanoparticles. Angew Chem Int Ed Engl 117:6208–6211CrossRef
63.
Zurück zum Zitat Rantanen T, Järvenpää ML, Vuojola J, Kuningas K, Soukka T (2008) Fluorescence-quenching-based enzyme-activity assay by using photon upconversion. Angew Chem Int Ed 47:3811–3813CrossRef Rantanen T, Järvenpää ML, Vuojola J, Kuningas K, Soukka T (2008) Fluorescence-quenching-based enzyme-activity assay by using photon upconversion. Angew Chem Int Ed 47:3811–3813CrossRef
64.
Zurück zum Zitat Ouellette AL, Li JJ, Cooper DE, Ricco AJ, Kovacs GTA (2009) Evolving point-of-care diagnostics using up-converting phosphor bioanalytical systems. Anal Chem 81:3216–3221CrossRef Ouellette AL, Li JJ, Cooper DE, Ricco AJ, Kovacs GTA (2009) Evolving point-of-care diagnostics using up-converting phosphor bioanalytical systems. Anal Chem 81:3216–3221CrossRef
65.
Zurück zum Zitat Achatz DE, Meier RJ, Fischer LH, Wolfbeis OS (2010) Luminescent sensing of oxygen using a quenchable probe along with upconverting nanoparticles. Angew Chem Intl Ed 49 (in press). DOI: 10.1002/anie.201004902 Achatz DE, Meier RJ, Fischer LH, Wolfbeis OS (2010) Luminescent sensing of oxygen using a quenchable probe along with upconverting nanoparticles. Angew Chem Intl Ed 49 (in press). DOI: 10.1002/anie.201004902
66.
Zurück zum Zitat Saleh SM, Ali R, Hirsch T, Wolfbeis OS (2010) Optical detection of biotin-avidin affinity binding by exploiting a self-referenced system composed of upconverting nanoparticles and gold nanoparticles. Biosens Bioelectron (Submitted) Saleh SM, Ali R, Hirsch T, Wolfbeis OS (2010) Optical detection of biotin-avidin affinity binding by exploiting a self-referenced system composed of upconverting nanoparticles and gold nanoparticles. Biosens Bioelectron (Submitted)
Metadaten
Titel
Luminescent Chemical Sensing, Biosensing, and Screening Using Upconverting Nanoparticles
verfasst von
Daniela E. Achatz
Reham Ali
Otto S. Wolfbeis
Copyright-Jahr
2011
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/128_2010_98

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.