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Erschienen in:
An Introduction to the Biomechanics of the Nervous System Kapitel lesen Erstes Kapitel lesen

2011 | OriginalPaper | Buchkapitel

Constitutive Modelling of Brain Tissue for Prediction of Traumatic Brain Injury

verfasst von : J. A. W. van Dommelen, M. Hrapko, G. W. M. Peters

Erschienen in: Neural Tissue Biomechanics

Verlag: Springer Berlin Heidelberg

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Abstract

To develop protective measures for crash situations, an accurate assessment of injury risk is required. By using a Finite Element model of the head, the mechanical behaviour of the brain can be predicted for any acceleration and improved injury criteria can be developed and implemented into safety standards. Many head models are based on a detailed geometrical description of the anatomical components. However, for reliable predictions of injury, also an accurate constitutive model for brain tissue is required that is applicable for large deformations and complex loading conditions that occur during an impact to the head. This chapter deals with constitutive modelling of brain tissue. Different approaches towards modelling of the mechanical response of biological tissues are discussed. A short overview of the large strain behaviour of brain tissue and constitutive models that have been developed for this material is given. A non-linear viscoelastic model for brain tissue is then discussed in more detail. The model is based on a multi-mode Maxwell model and consists of a non-linear elastic mode in combination with a number of viscoelastic modes. For this model, also a numerical implementation scheme is given. The influences of constitutive non-linearities of brain tissue in numerical head model simulations are shown by comparing the performance of the model of Hrapko et al. with a simplified version, based on neo-Hookean elastic behaviour, and a third non-linear constitutive model from literature.

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Vorheriges Kapitel Spinal Cord Mechanical Properties
Nächstes Kapitel Modeling of the Brain for Injury Prevention
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Fußnoten
1
It is important to make a clear distinction between functional and mechanical damage. Functional damage can be considered as injury, i.e. change or loss of functionality of the brain tissue, whereas mechanical damage only affects the mechanical properties of the tissue. At these strain levels, functional damage may still occur (as observed by for example Bain and Meaney [2] and Morrison et al. [33]) and at larger time scales also mechanical changes could develop.
 
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Metadaten
Titel
Constitutive Modelling of Brain Tissue for Prediction of Traumatic Brain Injury
verfasst von
J. A. W. van Dommelen
M. Hrapko
G. W. M. Peters
Copyright-Jahr
2011
Verlag
Springer Berlin Heidelberg
Buch
Neural Tissue Biomechanics

Print ISBN: 978-3-642-13889-8

Electronic ISBN: 978-3-642-13890-4

Copyright-Jahr: 2011

DOI
https://doi.org/10.1007/8415_2010_16

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