Abstract
We saw in Chap. 5 different mechanisms of molecular assembly onto surfaces. These mechanisms also play a role in molecular assembly onto Bio/CMOS surfaces. In this chapter, we will show how to use DNA short oligonucleotides or antibodies (Chap. 3) to develop Bio/CMOS interfaces to sense DNA hybridization or to provide antigen detection. The chapter also shows how different kinds of adsorption mechanisms and different kinds of DNA monolayers produce different Bio/CMOS interfaces with completely different electrical behaviors. In particular, the chapter shows how to use special alkanethiols to improve the quality of these probe surfaces on the nanoscale. We will see that the nanoscale quality of the Bio/CMOS interface is so important that, in some cases, this means we can have the sensing or if we fail on that.
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Carrara, S. (2013). Nanotechnology to Prevent Electron Transfer. In: Bio/CMOS Interfaces and Co-Design. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4690-3_6
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DOI: https://doi.org/10.1007/978-1-4614-4690-3_6
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