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Mechanisms of Drug Efflux and Strategies to Overcome Them as a Way to Control Microbial Growth

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New Weapons to Control Bacterial Growth

Abstract

The discovery of antibacterials during the twentieth century has been one of the most important events in the history of medicine. The development, production, and use of these new drugs revolutionized clinical practice and industrial microbiology. Certainly, since the beginning of the antibiotic era many lives have been saved. Nevertheless, shortly after the first descriptions of the effects of antibiotics against pathogenic bacteria, the phenomenon of antimicrobial resistance began to be quoted by different researchers. At first, this was not considered a significant clinical event.

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Authors and Affiliations

  1. Department of Microbiology, Biotechnology Unit, Faculty of Pharmacy, University of Santiago de Compostela, 15706, Santiago de Compostela, Spain

    T. de Miguel, J. L. R. Rama, L. Feijoo-Siota & J. M. Ageitos

  2. Department of Pathology and Experimental Therapeutics, University of Barcelona, Barcelona, Spain

    M. Viñas

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  1. T. de Miguel
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  2. J. L. R. Rama
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  3. L. Feijoo-Siota
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  4. J. M. Ageitos
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  5. M. Viñas
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Correspondence to T. de Miguel .

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Editors and Affiliations

  1. Faculty of Pharmacy, University of Santiago de Compostel, Santiago de Compostela, Spain

    Tomas G. Villa

  2. Faculty of Medicine, University of Barcelona, L'Hospitalet de Llobregat, Spain

    Miguel Vinas

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de Miguel, T., Rama, J.L.R., Feijoo-Siota, L., Ageitos, J.M., Viñas, M. (2016). Mechanisms of Drug Efflux and Strategies to Overcome Them as a Way to Control Microbial Growth. In: Villa, T., Vinas, M. (eds) New Weapons to Control Bacterial Growth. Springer, Cham. https://doi.org/10.1007/978-3-319-28368-5_6

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