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Pharmaceuticals

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Book cover Genetic Modification of Plants

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 64))

Abstract

Plants and plant cell cultures have been evaluated over the past two decades as alternative production platforms for biopharmaceuticals. A large number of candidate proteins has been successfully produced in a range of plant species and the most advanced products are currently progressing through the clinical development stages. We first discuss principles for the production of plant-made pharmaceuticals including plant transformation procedures, post-translational modifications, and downstream processing. We then highlight some of the most advanced plant-made biopharmaceuticals currently in clinical development for human medical use.

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Authors and Affiliations

  1. Department of Plant Biotechnology, Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Forckenbeckstrasse 6, 52074, Aachen, Germany

    Andreas Schiermeyer & Stefan Schillberg

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  1. Andreas Schiermeyer
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  2. Stefan Schillberg
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Correspondence to Andreas Schiermeyer .

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Editors and Affiliations

  1. Botanisches Institut, Universität Kiel, Olshausenstr. 40, Kiel, 24118, Germany

    Frank Kempken

  2. Inst. Pflanzenbau und Pflanzenzüchtung, Universität Kiel, Olshausenstr. 40, Kiel, 24098, Germany

    Christian Jung

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Schiermeyer, A., Schillberg, S. (2010). Pharmaceuticals. In: Kempken, F., Jung, C. (eds) Genetic Modification of Plants. Biotechnology in Agriculture and Forestry, vol 64. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02391-0_12

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