Abstract
This chapter summarizes current knowledge on the biochemical and physiological events leading to the massive accumulation of organic acids by filamentous fungi, particularly Aspergillus niger under industrially comparable conditions, thereby particularly emphasizing the roles of: (1) metabolic flux and its control and (2) critical fermentation variables. The value of genome information for metabolic analysis and genomic approaches in understanding these fermentations is also discussed.
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Notes
- 1.
5Fermentation is here used in a more general sense and means a “metabolic production process” as such and does not refer to an anaerobic sugar conversion process leading mainly to ethanol (see alcohol fermentation in Chapter 2).
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Kubicek, C.P., Punt, P., Visser, J. (2011). Production of Organic Acids by Filamentous Fungi. In: Hofrichter, M. (eds) Industrial Applications. The Mycota, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11458-8_10
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