Metabolic Engineering of Plant Secondary Metabolism

1. Front Matter

   Pages i-xi

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2. Secondary Metabolism

   • R. Verpoorte

   Pages 1-29

3. General Strategies

   • R. Verpoorte, R. Van Der Heijden, J. Memelink

   Pages 31-50

4. Agrobacterium, A Natural Metabolic Engineer of Plants

   • P. J. J. Hooykaas

   Pages 51-67

5. Particle Gun Methodology as a Tool in Metabolic Engineering

   • M. J. Leech, D. Burtin, D. Hallard, F. Hilliou, B. Kemp, N. Palacios et al.

   Pages 69-86

6. Modulation of Plant Function and Plant Pathogens by Antibody Expression

   • R. Fischer, J. Drossard, S. Schillberg, O. Artsaenko, N. Emans, J. M. Naehring

   Pages 87-109

7. Transcriptional Regulators to Modify Secondary Metabolism

   • J. Memelink, F. L. H. Menke, L. Van Der Fits, J. W. Kijne

   Pages 111-125

8. Plant Colour and Fragrance

   • K. M. Davies

   Pages 127-163

9. Metabolic Engineering of Condensed Tannins and other Phenolic Pathways in Forage and Fodder Crops

   • M. P. Robbins, P. Morris

   Pages 165-177

10. Metabolic Engineering of Crops with the Tryptophan Decarboxylase of Catharanthus Roseus

    • V. De Luca

    Pages 179-194

11. Genetic Engineering of Enzymes Diverting Amino Acids into Secondary Metabolism

    • J. Berlin, L. F. Fecker

    Pages 195-216

12. Modification of Plant Secondary Metabolism by Genetic Engineering

    • R. Hain, B. Grimmig

    Pages 217-231

13. Expression of the Bacterial ubiC Gene Opens a New Biosynthetic Pathway in Plants

    • L. Heide

    Pages 233-251

14. Regulation of Tropane Alkaloid Metabolism in Plants and Plant Cell Cultures

    • K-M. Oksman-Caldentey, R. Arroo

    Pages 253-281

15. Back Matter

    Pages 283-286

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Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites.
The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites.
No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.

• Expression
• Grove
• Ornamental plant
• Pathogen
• Tryptophan
• plant pathogens
• quality
• regulation
• biochemical engineering

`The book can be recommended to anyone wishing to start manipulation of secondary plant metabolism.'
Journal of Plant Physiology, 158:7 (2000)
`The book is a wonderful up-to-date comprehensive overview of the plant secondary metabolites field and will be very useful for plant biotechnologists. Moreover, this review is also suitable fo students and more generally for a broader readership.'
Plant Science, 161:201(2001)P

• Division of Pharmacognosy, Leiden/Amstredam Center for Drug Research, Leiden, The Netherlands

  Robert Verpoorte

• Institut für Entwicklungs- und Molekularbiologie der Pflanzen, Heinrich-Heine-Universität, Düsseldorf, Düsseldorf, Germany

  A. W. Alfermann

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