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EEG frequency content related to regional blood flow of cerebral cortex in cat

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Summary

The EEG frequency content in cats, anaesthetized by Nembutal and artificially ventilated, was altered by means of injections of either additional Nembutal or of Metrazol. The EEG in cerveau isolé preparations was also changed in the same way. The regional cortical blood flow was determined by means of the 85Krypton technique. A high correlation was found between the frequency content of the EEG, measured by means of manual frequency analysis, and the regional cortical blood flow. The cortical blood flow increased when the mean frequency increased, and vice versa. A similar correlation was found when the EEG mean frequency was changed by means of sensory stimulation.

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References

  • Betz, E., D.H. Ingvar, N.A. Lassen and F.W. Schmahl: Regional cerebral cortex, measured simultaneously by heat and inert gas clearance. Acta physiol. scand. 67, 1–9 (1966).

    Google Scholar 

  • Brazier, M.A.B., and J.E.A. Finesinger: A study of the occipital cortical potentials in 500 normal adults. J. clin. Invest. 223, 303–311 (1944).

    Google Scholar 

  • Curry, H.B., and D.H. Ingvar: Observations of the cortical blood flow during epileptic seizures. Electroenceph. clin. Neurophysiol. 14, 589 (1962).

    Google Scholar 

  • Espagno, J., et Y. Lazorthes: La mesure du dèbit sanguin cérebral local de l'homme par l'injection intraparenchymateuse de Xenon 133. Principes et premiers résultats. Presse méd. 74, 1881–1885 (1966).

    Google Scholar 

  • Fog, M.: Om piaarteriernes vasomotorieske reaktioner, 183 pp. Copenhagen: Munksgaard 1934.

    Google Scholar 

  • Freeman, J., and D.H. Ingvar: Elimination by hypoxia of cerebral blood flow autoregulation and EEG relationship. Exp. Brain Res. 5, 61–71 (1968).

    Google Scholar 

  • Gleichmann, U., D.H. Ingvar, N.A. Lassen, D.W. Lübbers, B.K. Siesjö and G. Thews: Regional cerebral cortical metabolic rate of oxygen and dioxide, related to EEG in the anaesthetized dog. Acta physiol. scand. 55, 82–94 (1962).

    Google Scholar 

  • Harper, A.M.: Autoregulation of cerebral blood flow; the influence of the arterial blood pressure on the blood flow through the cerebral cortex. J. Neurol. Neurosurg. Psychiat. 29, 398–403 (1966).

    Google Scholar 

  • Häggendal, E.: Blood flow autoregulation of the cerebral gray matter with comments on its mechanism. Acta neurol. scand., Suppl. 14, 104–110 (1965).

    Google Scholar 

  • Høedt-Rasmussen, K., E. Sveinsdottir and N.A. Lassen: The inert gas intra-arterial injection method for determining regional cerebral blood flow in man through the intact scull. Circulat. Res. 18, 237–247 (1966).

    Google Scholar 

  • Ingvar, D.H.: Extraneuronal influences upon the electrical activity of isolated cortex following stimulation of the reticular activating system. Acta physiol. scand. 33, 169–193 (1955).

    Google Scholar 

  • —: Cortical state of excitability and cortical circulation. In: Reticular formation of the brain, pp. 381–408. Ed. by H.H. Jasper et al. Boston: Little, Brown and Company 1958.

    Google Scholar 

  • —, M. Baldy-Moulinier, I. Sulg and S. Hörman: Regional cerebral blood flow related to EEG. Acta neurol. scand. 41, Suppl. 14, 179–182 (1965).

    Google Scholar 

  • —, and N.A. Lassen: Regional blood flow of the cerebral cortex determined by krypton 85. Acta physiol. scand. 54, 325–338 (1962).

    Google Scholar 

  • Ingvar, D.H., and I. Sulg: Regional cerebral blood flow and EEG frequency content in man. To be published 1968.

  • —, and U. Söderberg: A new method for measuring cerebral blood flow in relation to the electroencephalogram. Electroenceph. clin. Neurophysiol. 8, 403–412 (1956).

    Google Scholar 

  • Lassen, N.A.: Cerebral blood flow and oxygen consumption in man. Physiol. Rev. 39, 183–238 (1959).

    Google Scholar 

  • —, and D.H. Ingvar: The blood flow of the cerebral cortex determined by radioactive krypton 85. Experientia (Basel) 17, 42 (1961).

    Google Scholar 

  • Mc Ilwain, H.: Biochemistry and the central nervous system, 412 pp. London: Churchill Ltd. 1966.

    Google Scholar 

  • Obrist, W.D., L. Sokoloff, N.A. Lassen, M.H. Lane, R.N. Butler and I. Feinberg: Relation of EEG to cerebral blood flow and metabolism in old age. Electroenceph. clin. Neurophysiol. 15, 610–619 (1963).

    Google Scholar 

  • Roy, C.S., and C.S. Sherrington: The regulation of the blood supply of the brain. J. Physiol. (Lond.) 11, 85–108 (1890).

    Google Scholar 

  • Schmidt, C.F.: The cerebral circulation in health and disease, 78 pp. Springfield, Ill.: Ch. C. Thomas 1950.

    Google Scholar 

  • Sulg, I.: Manual EEG analysis. To be published 1968.

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On leave of absence from the University of Montpellier, France.

This investigation was sponsored by the Swedish Medical Research Council (Project 21x-84-01 and 21x-84-02) and by the Wallenberg Foundation, Stockholm.

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Baldy-Moulinier, M., Ingvar, D.H. EEG frequency content related to regional blood flow of cerebral cortex in cat. Exp Brain Res 5, 55–60 (1968). https://doi.org/10.1007/BF00239905

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