Skip to main content
Log in

Unusual blink reflex with four components in a patient with periodic ataxia

  • Short Communications
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Summary

Characteristic findings in blink reflex are reported in a 55-year-old female with periodic ataxia. The blink reflexes on the side ipsilateral to the stimulation consisted of four components with latencies of 11, 21, 35 and 47 ms, instead of the usual two components seen in normal subjects. On the contralateral side, the last three components were also present. The second component was different from the normal R2 response in that its latency was shorter than normal and it did not habituate by stimulation at a rate of 10 Hz. In addition, it was more affected by diazepam than the third or fourth components. It is considered that R2 may have consisted of three components and that a shorter latency of the second component could be explained by facilitation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Bouchard JP, Roberge C, Gelder NM, Barbeau A (1984) Familial periodic ataxia responsive to acetazolamide. Can J Neurol Sci 11:550–553

    Google Scholar 

  2. Donat JR, Auger R (1979) Familial periodic ataxia. Arch Neurol 36:568–569

    Google Scholar 

  3. Farmer TW, Mustian VM, Hill C (1963) Vestibulocerebellar ataxia. Arch Neurol 8:21–30

    Google Scholar 

  4. Gribbs RC, Moxley RT, Lafrance RA, McQuillen J (1978) Hereditary paroxysmal ataxia: response to acetazolamide. Neurology 28:1259–1264

    Google Scholar 

  5. Hill W, Sherman H (1968) Acute intermittent familial cerebellar ataxia. Arch Neurol 18:350–357

    Google Scholar 

  6. Kimura J (1973) Disorder of interneurons in Parkinsonism. The orbicularis oculi reflex to paired stimuli. Brain 96:87–96

    Google Scholar 

  7. Ongerboer de Visser W, Kuypers HGJM (1978) Late blink changes in lateral medullary lesions. An electrophysiological and neuro-anatomical study of Wallenberg's syndrome. Brain 101:285–294

    Google Scholar 

  8. Parker HL (1947) Periodic ataxia in collected papers of the Mayo Clinic and the Mayo Foundation, 1946. Saunders, Philadelphia, p 642

    Google Scholar 

  9. Wechsler LR, Stakes JW, Shahani BT, Busis NA (1986) Periodic leg movements of sleep (nocturnal myoclonus): an electrophysiological study. Ann Neurol 19:168–173

    Google Scholar 

  10. White JC (1966) Familial periodic nystagmus, vertigo, and ataxia. Arch Neurol 20:276–280

    Google Scholar 

  11. Young RR, Shahani BT (1979) Clinical neurophysiological aspects of post-hypoxic intention myoclonus. In: Fahn S, Davis JN, Rowland LP (eds) Advances in neurology: cerebral hypoxia and its consequences, vol 26. Raven, New York, pp 85–105

    Google Scholar 

  12. Zasorin NL, Baloh RW, Myers LB (1983) Acetazolamide-responsive episodic ataxia syndrome. Neurology 33:1212–1214

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yokota, T., Hayashi, H., Hirose, K. et al. Unusual blink reflex with four components in a patient with periodic ataxia. J Neurol 237, 313–315 (1990). https://doi.org/10.1007/BF00314750

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00314750

Key words

Navigation