Zusammenfassung
Ein kurzdauernder polarisierender Strom blockiert die Impulsfortleitung in den A-Fasern eines Nerven, bleibt dagegen ohne Wirkung auf die C-Fasern. Der Block der A-Fasern ist reversibel. Bei hinreichend niedriger Anstiegsgeschwindigkeit werden durch den Blockstrom selbst keine A-Fasern gereizt.
Summary
A polarizing current applied transiently to a nerve selectively blocks conduction in the A-fibers, whereas the C-fibers remain unaffected. The block is reversible. Stimulation of A-fibers by the polarizing current is prevented by appropriately adjusting its slope of rise.
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References
Douglas, W. W., and J. M. Ritchie: Mammalian nonmyelinated nerve fibers. Physiol. Rev. 42, 297–334 (1962).
Mendell, L. M., and P. D. Wall: Presynaptic hyperpolarization: a role for fine afferent fibres. J. Physiol. (Lond.) 172, 274–294 (1964).
Paintal, A. S.: A comparision of the nerve impulses of mammalian non-medullated nerve fibers with those of the smallest diameter medullated fibres. J. Physiol. (Lond.) 193, 523–533 (1967).
Zimmermann, M.: Dorsal root potentials after C-fiber stimulation. Science 160, 896–898 (1968).
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This work was supported by the Deutsche Forschungsgemeinschaft.
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Zimmermann, M. Selective activation of C-fibers. Pflügers Archiv 301, 329–333 (1968). https://doi.org/10.1007/BF00362643
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DOI: https://doi.org/10.1007/BF00362643