Abstract
This paper presents an experimental method to measure the thermal conductivity and thermal diffusivity of biomaterials. Self-heated thermistor probes, inserted into the tissue of interest, are used to deliver heat as well as to monitor the rate of heat removal. An empirical calibration procedure allows accurate thermal-property measurements over a wide range of tissue temperatures. Operation of the instrument in three media with known thermal properties shows the uncertainty of measurements to be about 2%. The reproducibility is 0.5% for the thermal-conductivity measurements and 2% for the thermal-diffusivity measurements. Thermal properties were measured in dog, pig, rabbit, and human tissues. The tissues included kidney, spleen, liver, brain, heart, lung, pancreas, colon cancer, and breast cancer. Thermal properties were measured for 65 separate tissue samples at 3, 10, 17, 23, 30, 37, and 45°C. The results show that the temperature coefficient of biomaterials approximates that of water.
Similar content being viewed by others
References
T. A. Balasubranium and H. F. Bowman, J. Biochem. Eng. 99:148 (1977).
J. W. Valvano, J. T. Allen, and H. F. Bowman, J. Biomech. Eng. 106:192 (1984).
J. C. Chato (eds.), in Thermal Problems in Biotechnology (ASME, New York, 1968), pp. 16–25.
R. K. Jain, J. Biomech. Eng. 101:82 (1979).
K. R. Holmes and M. M. Chen, Physiologist 23:183 (1980).
L. J. Hayes and J. W. Valvano, J. Biomech. Eng. 107:77 (1985).
J. W. Valvano, P. A. Patel, and L. J. Hayes, in Advances in Bioengineering (ASME, New York, 1983), pp. 149–150.
Y. S. Touloukian, P. E. Liley, and S. C. Saxena, in Thermophysical Properties of Matter, The TPRC Data Series (IFI/Plenum, New York, 1970), Vol. 3, pp. 120, 209; Vol. 10, pp. 290, 589.
Y. L. Rastorguev and Y. A. Ganiev, Russ. J. Phys. Chem. 40:869 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Valvano, J.W., Cochran, J.R. & Diller, K.R. Thermal conductivity and diffusivity of biomaterials measured with self-heated thermistors. Int J Thermophys 6, 301–311 (1985). https://doi.org/10.1007/BF00522151
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00522151