Summary
The relationship between stroke volume (SV) measured simultaneously by impedance cardiography (SV1) and echocardiography (SVE) has been analyzed. Change in stroke volume in 6 healthy volunteers was induced by passive head-up tilting (80°) and by oral administration of the sympathomimetic drug amezinium. A correlation ofr=0.83 (p j 0.01) was found between SVI and SVE calculated by the equation: SVE=16.0+(0.528×SVI). Though stroke volume is overestimated by impedance cardiography, the method may be useful for the clinical pharmacologist interested in a simple non-invasive tool to estimate stroke volume and change in it.
Similar content being viewed by others
References
Baker LE, Judy WV, Geddes LE, Langley FM, Hill DW (1971) The measurement of cardiac output by means of the electrical impedance. Cardiovasc Res Cent Bull 9: 135–145
Belz GG, Aust PE, Belz G, Appel E, Palm D (1982) Sympathomimetic effects of amezinium on the cardiovascular system and plasma catecholamines in man. Eur J Clin Pharmacol 23: 15–20
Erbel R, Schweizer P (1980) Diagnostischer Stellenwert der Echokardiographie bei der koronaren Herzerkrankung — 1. M-mode-Echokardiographie. Z Kardiol 69: 391–397
Fortuin NJ, Hood WP, Craige E (1972) Evaluation of left ventricular function by echocardiography. Circulation 46: 26–35
Hill DW, Thompson FD (1975) The effect of hematocrit on the resistivity of human blood at 37 °C and 100 kHz. Med Biol Eng 13: 182–186
Kiowski W, Randall OS, Steffens TG, Julius S (1981) Reliability of echocardiography in assessing cardiac output. Klin Wochenschr 59: 1115–1120
Kubicek WG, Karnegis JN, Patterson RP, Witsoe DA, Mattson RH (1966) Development and evaluation of an impedance cardiac output system. Aerosp Med 37: 1208–1212
Kubicek WG, Kottke FJ, Ramos MU, Patterson RP, Witsoe DA, Labree JW, Remole W, Laymann TE, Schoening H, Garamela JT (1974) The Minnesota impedance cardiograph — theory and applications. Biomed Eng J 9: 410–416
Pombo JF, Troy BL, Russell RO (1971) Left ventricular volumes and ejection fraction by echocardiography. Circulation 43: 480–490
Simon G, Dickhuth HH, Keul J (1980) Auswirkungen der Beta-Rezeptorenblockade auf invasiv und echokardiographisch ermittelte hämodynamische Größen. Z Kardiol 69: 75–80
Stick C (1978) Die Reproduzierbarkeit impedanzkardiographischer Schlagvolumenbestimmungen. Z Kardiol 67: 863–867
Teichholz LE, Kreulen T, Herman MV, Gorlin R (1976) Problems in echocardiographic volume determinations: Echocardiographic-angiographic correlations in the presence or absence of asynergy. Am J Cardiol 37: 7–11
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Aust, P.E., Belz, G.G., Belz, G. et al. Comparison of impedance cardiography and echocardiography for measurement of stroke volume. Eur J Clin Pharmacol 23, 475–477 (1982). https://doi.org/10.1007/BF00637491
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00637491