Summary
Nearly quantitative conversion of linoleic acid to its hydroperoxide was achieved at room temperature (∼24°C) in microemulsions containing surfactant, water, and organic solvent, using air as the oxygen source, and lipoxygenase from soybeans as the catalyst, providing an excellent route to this strategic intermediate in the synthesis of important industrial products.
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Ayala, G. and Mendoza-Hernándes, G. (1991)Biochemistry International 22, 717–723.
Cardillo, R., Fronza, G., Fuganti, C., Grasselli, P., Mele, A., Pizzi, D., Allegrone, G., Barbeni, M., Pisciotta, A. (1991)O. Org. Chem. 56, 5237–5239.
Datcheva, V.K., Kiss, K., Solomon, L. and Kyler, K.S. (1991)J. Am. Chem. Soc. 113, 270–274.
Elworthy, P.H., Florence, A.T., and Macfarlane, C.B. (1968)Solubilization by Surface-Active Agents, Chapman and Hall, London.
Graveland A. (1973)Lipids 8, 606–611.
Han, D. and Rhee, J.S. (1986)Biotech. and Bioengin. 28, 1250–1255.
Iacazio, G., Langrand, G., Baratti, J., Buono, G. and Triantaphylidès, C. (1990)J. Org. Chem. 55, 1690–1691.
Jiang, Z.-Y., Woollard, A.C.S., and Wolff, S.P. (1991)Lipids 26, 853–856.
Linke, W.F., ed. (1965)Solubilities of Inorganic and Metal-organic Compounds, Vol. II, Forth Ed., American Chemical Society, Washington, DC.
Luisi, P.L., Lüthi, P., Tomka, I., Pande, A. (1984)Ann. N. Y. Acad. Sci. 434, 549–557.
Schirber, C.A. (1991)Inform 2, 1062–1072.
Vignolo, R. and Naughton, F. (1991)Inform 2, 692–699.
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Piazza, G.J. Lipoxygenase catalyzed hydroperoxide formation in microemulsions containing nonionic surfactant. Biotechnol Lett 14, 1153–1158 (1992). https://doi.org/10.1007/BF01027020
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DOI: https://doi.org/10.1007/BF01027020