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Development of new hydrophilic polymer supports based on dimethylacrylamide

  • Colloid Science
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Abstract

A survey of the development of hydrophilic resins based on dimethylacrylamide (DMA) is presented. It describes the preparation of DMA-based resins by suspension copolymerization of DMA and acrylamide-based crosslinking and functional monomers. Swellability data for a number of DMA-based resins are tabulated, demonstrating that the resins swell to approximately the same extent in dichloromethane as they do in water, methanol, dimethylformamide or dimethylsulphoxide, but they swell only slightly or not at all in tetrahydrofuran. Typical chemical reactions employed for quantitative estimation or derivatization of resin-bound functional groups, including those involving intra-resin crosslinking, are discussed. The development of composite polymer supports, in which the DMA-based polymer is supported on kieselguhr particles or an amphiphilic ion exchange polymer is supported on DMA-based resin beads, is also covered briefly.

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References

  1. Calmon C (1984) AIch E Symp Ser 80 (233):84

    Google Scholar 

  2. Dean PDG, Johnson WS, Middle FA (1985) Affinity Chromatography. IRL Press, Oxford

    Google Scholar 

  3. Merrifield RB (1963) J Am Chem Soc 85:2149

    Google Scholar 

  4. Smith LM (1988) Anal Chem:381

  5. Sproat BS, Gait MJ (1984) In: Gait MJ (ed) Oligonucleotide Synthesis, A Practical Approach. IRL Press, Oxford

    Google Scholar 

  6. Hartley FR (1985) Supported Metal Catalysts. D. Reidel, Doordrecht

    Google Scholar 

  7. Ford WT (ed) (1984) Polymeric Reagents and Catalysts. American Chemical Society, Washington DC

    Google Scholar 

  8. Ichiro I, Wingard LB Jr (eds) (1986) Applied Biochemistry Vol 4

  9. Arshady R, Ledwith A (1983) Reactive Polmyers 1:159

    Google Scholar 

  10. Munzer M, Trommsdorff E (1977) High Polym 29:106

    Google Scholar 

  11. Akelah A, Sherrington DC (1981) Chem Rev 18:557

    Google Scholar 

  12. Inman JK, Dintzis HM (1969) Biochemistry 8:4047

    Google Scholar 

  13. Grushka E (ed) (1974) Bonded Stationary Phases in Chromatography. Ann Arbour Science, Ann Arbour

    Google Scholar 

  14. Arshady R (1988) Makromol Chem 189:1295

    Google Scholar 

  15. Arshady R (1984) Makromol Chem 185:2317

    Google Scholar 

  16. Stark GR (ed) (1971) Biochemical Aspects of Reactions on Solid Supports. Academic Press, New York

    Google Scholar 

  17. Sheppard RC (1973) In: Nesvadba H (ed) Proc 11th Eur Peptide Symp. North Holland, Amsterdam p 111

    Google Scholar 

  18. Atherton E, Sheppard RC (1975) In: Wolman Y (ed) 13th Eur Peptide Symp. John Wiley, New York, p 123

    Google Scholar 

  19. Heidmann W, Koester H (1980) Makromol Chem 181:2495

    Google Scholar 

  20. Atherton E, Clive DLJ, Sheppard RC (1975) J Am Chem Soc 97:6584

    PubMed  Google Scholar 

  21. Arshady R, Atherton E, Clive DLJ, Sheppard RC (1981) J Chem Soc Perkin Trans I:529

    Google Scholar 

  22. Arshady R, Atherton E, Sheppard RC (1979) Chem Comm:423

  23. Stahl GL, Smith CW, Walter R (1981) Int J Peptide Protein Res 15:331

    Google Scholar 

  24. Arshady (1989) Angew Makromol Chem 170:43

    Google Scholar 

  25. Arshady R, Ugi I (1990) Polymer 31:1164

    Google Scholar 

  26. Atherton E, Gait MJ, Sheppard RC, Williams BJ (1979) Bioorg Chem 8:351; Sheppard RC (1986) Science Tools 33:9

    Google Scholar 

  27. Mitsui Toatsu Chemicals JP 59 20,259 84 20,259 CA 101:6640j

  28. Oshima A, Kazuhiko T JP Tokyo Koho 79 09,170 CA 91:75071

  29. Daniher FA, Visek K Ger Offen 2,344,070 CA 81:170202g

  30. Asahi Chem Ind Co Fr 2,046122 CA 76:46663r

  31. Halpern JA, Sparrow JT (1980) Synth Comm 10:569

    Google Scholar 

  32. Stahl GL, Walter R, Smith CW (1978) J Org Chem 43:2285

    Google Scholar 

  33. Arshady R (1982) Chem Ind (London):730

  34. Yocum RH, Nyquist EB (eds) (1973) Functional Monomers Vol 1. Marcel Dekker, New York

    Google Scholar 

  35. Dumitriu E, Oprea S, Maxim S, Nathanso A, Dima M (1979) Colloid Polym Sci 257:1203

    Google Scholar 

  36. North AM, Scallen AM (1964) Polymer 13:447

    Google Scholar 

  37. Arshady R (1988) Chem Ind (Milan) 70(9):70

    Google Scholar 

  38. Atherton E, Logan CL, Sheppard RC (1981) J Chem Soc Perkin Trans I:538

    Google Scholar 

  39. Arshady R, Atherthon E, Sheppard RC (1979) Tetrahedron Lett 17:1521

    Google Scholar 

  40. Arshady R, Ugi I (1981) Z Naturforsch 36b:1202

    Google Scholar 

  41. Arshady R, Basato M, Corain B, Roncato M, Zecca M, Della Giustina L, Lora S, Palma G (1989) J Mol Catal 53:111

    Google Scholar 

  42. Dryland A, Sheppard RC (1986) J Chem Soc Perkin Trans I:125

    Google Scholar 

  43. Arshady R (1982) Polymer 23:947

    Google Scholar 

  44. Arshady R (1982) Polymer 23:1870

    Google Scholar 

Download references

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  1. R. Arshady

    Present address: Department of Chemistry, Imperial College of Science and Technology, London, England

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    1. R. Arshady
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    Arshady, R. Development of new hydrophilic polymer supports based on dimethylacrylamide. Colloid & Polymer Sci 268, 948–958 (1990). https://doi.org/10.1007/BF01469374

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    • DOI: https://doi.org/10.1007/BF01469374

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