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Ionic selectivity revisited: The role of kinetic and equilibrium processes in ion permeation through channels

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References

  1. Adams, D.J., Dwyer, T.M., Hille, B. 1980.J. Gen. Physiol. 75:493–510

    PubMed  Google Scholar 

  2. Adams, D.J., Nonner, W., Dwyer, T.M., Hille, B. 1981.J. Gen. Physiol. 78:593–615

    PubMed  Google Scholar 

  3. Armstrong, C.M. 1975.In: Membranes, A Series of Advances. G. Eiseman, editor. Vol. 3, pp. 325–358. Marcel Dekker, New York

    Google Scholar 

  4. Begenisich, T. 1979.In: Membrane Transport Processes. C.F. Stevens and R.W. Tsien, editors. Vol. 3, pp. 105–111. Raven Press, New York

    Google Scholar 

  5. Begenisich, T., Stevens, C.F. 1975.Biophys. J. 15:843–846

    PubMed  Google Scholar 

  6. Begenisich, T.B., Cahalan, M.D. 1980.J. Physiol (London) 307:217–242

    Google Scholar 

  7. Begenisich, T.B., Cahalan, M.D. 1980.J. Physiol. (London) 307:243–257

    Google Scholar 

  8. Bezanilla, F., Armstrong, C.M. 1972.J. Gen. Physiol. 60:588–608

    Google Scholar 

  9. Boyle, P.J., Conway, E.J. 1941.J. Physiol. (London).100:163

    Google Scholar 

  10. Brickmann, J., Fischer, W. 1983. Entropy effects on the ion diffusion rate in transmembrane protein channels.Biophys. Chem. (in press)

  11. Brown, K.M., Dennis, J.E. 1972.Num. Math. 18:289–297

    Google Scholar 

  12. Bungenberg de Jong, H.G. 1949.In: Colloid Science. pp. 287. Elsevier, Amsterdam

    Google Scholar 

  13. Ciani, S. 1965.Biophysik. 2:368–378

    PubMed  Google Scholar 

  14. Ciani, S.M., Eisenman, G., Laprade, R., Szabo, G. 1973.In: Membranes, A Series of Advances. G. Eisenman, editor. Vol. 2, pp. 61–177. Marcel Dekker, New York

    Google Scholar 

  15. Colquhoun, D., Hawkes, A.G. 1981.Proc. R. Soc. London B 211:205–235

    Google Scholar 

  16. Coronado, R., Miller, C. 1982.J. Gen. Physiol. 79:529–547

    Google Scholar 

  17. Coronado, R., Rosenberg, R.L., Miller, C. 1980.J. Gen. Physiol. 76:425–446

    Google Scholar 

  18. Dani, J.A., Levitt, D.G. 1981.Biophys. J. 35:485–500

    PubMed  Google Scholar 

  19. Diamond, J.M., Wright, E. 1969.Annu. Rev. Physiol. 31:581–646

    PubMed  Google Scholar 

  20. Dwyer, T.M., Adams, D.J., Hille, B. 1980.J. Gen. Physiol. 75:469–492

    PubMed  Google Scholar 

  21. Eberl, D.D. 1980.Clays Clay Min. 28:161–172

    Google Scholar 

  22. Eigen, M., Winkler, R. 1970.In: The Neurosciences. F.O. Schmitt, editor. Vol. II, pp. 685–696. Rockefeller University Press, New York

    Google Scholar 

  23. Eisenman, G. 1961.In: Symposium on Membrane Transport and Metabolism. A. Kleinzeller and A. Kotyk, editors. pp. 163–179. Academic Press, New York

    Google Scholar 

  24. Eisenman, G. 1962.Biophys. J. 2 (2):259–323

    PubMed  Google Scholar 

  25. Eisenman, G. 1965.In: Proc. XXIIIrd Int. Congr.Physiol. Sci. (Tokyo) 87:489–506

  26. Eisenman, G. 1969.In: Ion-Selective Electrodes. R.A. Durst, editor. pp. 1–56. National Bureau of Standards Special Publication 314

  27. Eisenman, G. 1983.In: Mass Transfer and Kinetics on Ion Exchange. L. Liberti, editor. NATO Advanced Study Institute Series, Martinus Nijhoff Publ. (in press)

  28. Eisenman, G., Conti, F. 1965:J. Gen. Physiol. 48 (2):65–73

    PubMed  Google Scholar 

  29. Eisenman, G., Hagglund, J., Sandblom, J., Enos, B. 1980.Uppsala J. Med. Sci. 85:247–257

    Google Scholar 

  30. Eisenman, G., Krasne, S. 1975.In: MTP International Review of Science, Biochemistry Series. C.F. Fox, editor. Vol. 2, pp. 27–59. Butterworths, London

    Google Scholar 

  31. Eisenman, G., Krasne, S., Ciani, S. 1975.Ann. N.Y. Acad. Sci. 264:34–60

    PubMed  Google Scholar 

  32. Eisenman, G., Krasne, S., Ciani, S. 1976.In: Ion and Enzyme Electrodes in Medicine and in Biology. M. Kessler, L. Clark, D. Lubbers, I. Silver, and W. Simon, editors. pp. 3–22. Urban and Schwarzenberg, Munich-Berlin-Vienna

    Google Scholar 

  33. Eisenman, G., Rudin, D.O., Casby, J.U. 1957a.Science 126:831–834

    PubMed  Google Scholar 

  34. Eisenman, G., Rudin, D.O., Casby, J.U. 1957b.In: 10th Annual Conference on Electrical Techniques in Medicine and Biology of the A.I.E.E., I.S.A., and I.R.E., Boston

  35. Eisenman, G., Sandblom, J.P. 1983.In: Physical Chemistry of Transmembrane Motions. G. Spach, editor. pp. 329–347. Elsevier, Amsterdam

    Google Scholar 

  36. Eisenman, G., Sandblom, J., Hagglund, J. 1983.In: Structure and Function in Excitable Cells. W. Adelman, D. Chang, R. Leuchtag, and I. Tasaki, editors. Plenum, New York (in press)

    Google Scholar 

  37. Eisenman, G., Sandblom, J., Neher, E. 1977.In: Metal-Ligand Interactiions in Organic Chemistry and Biochemistry. Vol. 9, Part 2. B. Pullman and N. Goldblum, editors. pp. 1–36. Reidel, Dordrecht

    Google Scholar 

  38. Eisenman, G., Sandblom, J., Neher, E. 1978.Biophys. J. 22:307–340

    PubMed  Google Scholar 

  39. Eisenman, G., Szabo, G., Ciani, S., McLaughlin, S., Krasne, S. 1973.Prog. Surf. Membr. Sci. 6:139–241

    Google Scholar 

  40. Eyring, H., Lumry, R., Woodbury, J.W. 1949.Rec. Chem. Prog. 10:100–114

    Google Scholar 

  41. Finkelstein, A., Andersen, O.S. 1981.J. Membrane Biol. 59:155–171

    Google Scholar 

  42. Fischbach, G.D., Lass, Y. 1978.J. Physiol. (London) 280:527–536

    Google Scholar 

  43. Fischer, W., Brickmann, J. 1983.In: Physical Chemistry of Transmembrane Motions. G. Spach, editor. pp. 415–422. Elsevier Amsterdam

    Google Scholar 

  44. Fischer, W., Brickmann, J., Lauger, P. 1981.Biophys. Chem. 13:105–116

    PubMed  Google Scholar 

  45. Frehland, E., Stephan, W. 1979.Biochim. Biophys. Acta 553:326–341

    PubMed  Google Scholar 

  46. Gage, P.W., Helden, D.F. van 1979.J. Physiol. (London) 288:509–528

    Google Scholar 

  47. Gay, L.A., Stanfield, P.R. 1978.Nature (London) 276:169–170

    Google Scholar 

  48. Glasstone, S., Laudler, K.J., Eyring, H. 1941. The Theory of Rate Processes. McGraw-Hill, New York

    Google Scholar 

  49. Goldman, D. 1943.J. Gen. Physiol. 27:37–60

    Google Scholar 

  50. Gorman, A.L.F., Woolum, J.C., Cornwall, M.D. 1982.Biophys. J. 38:319–322

    PubMed  Google Scholar 

  51. Grell, E., Funck, T., Eggers, F. 1975.In: Membranes, A Series of Advances. G. Eisenman, editor. Vol. 3, pp. 1–126. Marcel Dekker, New York

    Google Scholar 

  52. Gresh, N., Etchebest, C., Luz Rojas de la, O., Pullman, A. 1981.Int. J. Quant. Chem. 8:109–116

    Google Scholar 

  53. Gresh, N., Pullman, A. 1982. A theoretical study of the interaction of nonactin with Na+, and NH +4 .Int. J. Quant. Chem. (in press)

  54. Hille, B. 1971.J. Gen. Physiol. 58:599–619

    PubMed  Google Scholar 

  55. Hille, B. 1972.J. Gen. Physiol. 59:637–658

    Google Scholar 

  56. Hille, B. 1973.J. Gen. Physiol. 61:669–686

    Google Scholar 

  57. Hille, B. 1975a.In: Membranes, A Series of Advances. G. Eisenman, editor. Vol. 3, pp. 255–323. Marcel Dekker, New York

    Google Scholar 

  58. Hille, B. 1975b.J. Gen. Physiol. 66:535–560

    Google Scholar 

  59. Hille, B., Schwarz, W. 1978.J. Gen. Physiol. 72:409–442

    PubMed  Google Scholar 

  60. Hladky, S.B., Haydon, D.A. 1972.Biochim. Biophys. Acta 274:294–312

    PubMed  Google Scholar 

  61. Hladky, S.B., Urban, B.W., Haydon, D.A. 1979.In: Membrane Transport Processes. C.F. Stevens and R.W. Tsien, editors. Vol. 3, pp. 89–103. Raven Press, New York

    Google Scholar 

  62. Hober, R. 1905.Pflugers Arch. Ges. Physiol. 106:599–635

    Google Scholar 

  63. Hodgkin, A.L., Katz, B. 1949.J. Physiol. (London) 108:37–77

    Google Scholar 

  64. Hodgkin, A.L., Keynes, R.D. 1955.J. Physiol. (London) 128:61–88

    Google Scholar 

  65. Hoffman, H.M., Dionne, V.E. 1982.Biophys. J. 37:19a

    Google Scholar 

  66. Horn, R., Brodwick, M.S. 1980.J. Gen. Physiol. 75:297–321

    PubMed  Google Scholar 

  67. Horn, R., Brodwick, M.S., Dickey, W.D. 1980.Science 210:205–207

    PubMed  Google Scholar 

  68. Horn, R., Patlak, J., Stevens, C.J. 1981.Biophys. J. 36:321–327

    PubMed  Google Scholar 

  69. Horn, R., Stevens, C.F. 1980.Comm. Mol. Cell. Biophys. 1:57–68

    Google Scholar 

  70. Huang, L-Y.M., Catterall, W.A., Ehrenstein, G. 1978.J. Gen. Physiol. 71:397–410

    PubMed  Google Scholar 

  71. Jack, J.J.B., Noble, D., Tsien, R.W. 1975. The Spread of Current in Excitable Cells. Clarendon Press, Oxford

    Google Scholar 

  72. Jenny, H. 1932.J. Physiol. Chem. 36:2217–2258

    Google Scholar 

  73. Karplus, M., McCammon, J.A. 1981.CRC Crit. Rev. Biochem. 9:293–349

    PubMed  Google Scholar 

  74. Karreman, G., Eisenman, G. 1962.Bull. Math. Biophys. 24:413–427

    Google Scholar 

  75. Kohler, H.-H., Heckmann, K. 1980.J. Membr. Sci. 6:45–59

    Google Scholar 

  76. Koyama, Y., Shimanouchi, T. 1974.In: Peptides, Polypeptides and Proteins. E.R. Blout, F.A. Bovey, M. Goodman, and N. Lotan, editors. pp. 396–418. John Wiley, New York

    Google Scholar 

  77. Krasne, S. 1978.In: Physiology of Membrane Disorders. T.E. Andreoli, J.F. Hoffman, and D.D. Fanestil, editors. Ch. 12, pp. 217–241. Plenum Medical, New York

    Google Scholar 

  78. Krasne, S., Eisenman, G. 1973.In: Membranes, A Series of Advances. G. Eisenman, editor. Vol. 2, pp. 277–328. Marcel Dekker, New York

    Google Scholar 

  79. Krasner, S., Eisenman, G. 1976.J. Membrane Biol. 30:1–44

    Google Scholar 

  80. Laprade, R., Ciani, S., Eisenman, G., Szabo, G. 1975.In: Membranes, A Series of Advances. G. Eisenman, editor. Vol. 3, pp. 127–214. Marcel Dekker, New York

    Google Scholar 

  81. Latorre, R., Miller, C. 1983.J. Membrane Biol. 71:11–30

    Google Scholar 

  82. Lauger, P. 1973.Biochim. Biophys. Acta 311:423–441

    PubMed  Google Scholar 

  83. Lauger, P. 1979.Biochim. Biophys. Acta 557:283–294

    PubMed  Google Scholar 

  84. Lauger, P. 1980.J. Membrane Biol. 57:163–178

    Google Scholar 

  85. Lauger, P. 1982.Biophys. Chem. 15:89–100

    PubMed  Google Scholar 

  86. Lauger, P., Stephan, W., Frehland, E. 1980.Biochim. Biophys. Acta 602:167–180

    PubMed  Google Scholar 

  87. Levitt, D.G. 1982.Biophys. J. 37:575–587

    PubMed  Google Scholar 

  88. Lewis, C. 1979.J. Physiol. (London) 286:417–445

    Google Scholar 

  89. Lindley, B.D., Hoshiko, T. 1964J. Gen. Physiol. 47:749–771

    Google Scholar 

  90. Ling, G.N. 1952.In: Phosphorus Metabolism. W.D. McElroy and B. Glass, editors. Vol. II, pp. 748–795. Johns Hopkins, Baltimore

    Google Scholar 

  91. Ling, G.N. 1962. A Physical Theory of the Living State. Ginn (Blaisdell), Boston

    Google Scholar 

  92. Loftfield, R.B., Eigner, E.A., Pastuszyn, A., Lovgren, T.N.E., Jakubowski, H. 1980.Proc. Natl. Acad. Sci. USA 77:3374–3378

    PubMed  Google Scholar 

  93. Marchais, D., Marty, A. 1979.J. Physiol. (London) 297:9–45

    Google Scholar 

  94. Marty, A. 1981.Nature (London) 291:497–500

    Google Scholar 

  95. Mattock, G. 1961. pH Measurement and Titration. pp. 130–134. Heywood, London

    Google Scholar 

  96. McBride, D.W. 1981. Anomalous Mole Fraction Behavior, Momentary Block, and Lifetimes of Gramicidin A in Silver and Potassium Fluoride Solutions. Ph.D. Thesis, University of California, Los Angeles

    Google Scholar 

  97. Michaelis, L. 1925.J. Gen. Physiol. 8:33–59

    Google Scholar 

  98. Miller, C. 1982a.In: Transport in Biological Membranes. R. Antolini, editor. pp. 99–108. Raven Press, New York

    Google Scholar 

  99. Miller, C. 1982b.J. Gen. Physiol. 79:869–891

    PubMed  Google Scholar 

  100. Morf, W.E. 1981. The Principles of Ion-Selective Electrodes and of Membrane Transport. Elsevier, Amsterdam

    Google Scholar 

  101. Mullins, L.J. 1959.J. Gen. Physiol. 42:817–829

    PubMed  Google Scholar 

  102. Mullins, L.J. 1975.Biophys. J. 15:921–931

    PubMed  Google Scholar 

  103. Myers, V.B., Haydon, D.A. 1972.Biochim. Biophys. Acta 274:313–322

    PubMed  Google Scholar 

  104. Neher, E., Steinbach, J.H. 1978.J. Physiol. (London) 277:153–176

    Google Scholar 

  105. Pallotta, B.S., Magleby, K.L., Barrett, J.N. 1981.Nature (London) 293:471–474

    Google Scholar 

  106. Pauling, L. 1960. The Nature of the Chemical Bond. (3rd. Ed.) Cornell University, Ithaca

    Google Scholar 

  107. Procopio, J., Andersen, O.S. 1979.Biophys. J. 25:8a

    Google Scholar 

  108. Reichenberg, D. 1966.In: Ion Exchange, A Series of Advances. J.A. Marinsky, editor. Vol. 1, pp. 227–276. Marcel Dekker, New York

    Google Scholar 

  109. Reid, E.W. 1898.In: Textbook in Physiology. E.A. Schafer, editor. Young J. Pentland, Edinburgh

    Google Scholar 

  110. Reuter, H., Stevens, C.F. 1981.J. Membrane Biol. 57:103–118

    Google Scholar 

  111. Ring, A., Sandblom, J. 1983.J. Memb. Sci. (in press)

  112. Sachs, F., Lecar, H. 1977.Biophys. J. 17:129–143

    PubMed  Google Scholar 

  113. Sandblom, J., Eisenman, G., Hagglund, J.V. 1983.J. Memb. Biol. 71:61–78

    Google Scholar 

  114. Sandblom, J., Eisenman, G., Neher, E. 1977.J. Membrane Biol. 31:383–417

    Google Scholar 

  115. Schagina, L.V., Grinfeldt, A.E., Lev, A.A. 1978.Nature (London) 273:243–245

    Google Scholar 

  116. Schroder, H. 1983. Rate theoretical analysis of ion transport in membrane channels with elastically bound ligands.In. Physical Chemistry of Transmembrane Motions. G. Spach, editor. pp. 425–436. Elsevier, Amsterdam

    Google Scholar 

  117. Sherry, H.S. 1969.In: Ion Exchange. J. Marinsky, editor. pp. 89–133. Marcel Dekker, New York

    Google Scholar 

  118. Sigworth, F.J. 1982.Biophys. J. 37:309a

    Google Scholar 

  119. Simon, W., Morf, W.E. 1973.In: Membranes. A Series of Advances. G. Eisenman, editor. pp. 329–375. Marcel Dekker, New York

    Google Scholar 

  120. Swenson, R.P., Armstrong, C.M. 1981.Nature (London) 291:427–429

    Google Scholar 

  121. Takeda, K., Barry, P.H., Gage, P.W. 1982.Proc. R. Soc. London B. 216:225–251

    Google Scholar 

  122. Thomas, R.C., Meech, R.W. 1982.Nature (London) 299:826–828

    Google Scholar 

  123. Truesdell, A.H., Christ, C.L. 1967.In: Glass Electrodes for Hydrogen and Other Cations. G. Eisenman, editor. Ch. 11, pp. 293–321. M. Dekker, New York

    Google Scholar 

  124. Urban, B.W., Hladky, S.B. 1979.Biochim. Biophys. Acta 554:410–429

    Google Scholar 

  125. Urban, B.W., Hladky, S.B., Haydon, D.A. 1980.Biochim. Biophys. Acta 602:331–354

    PubMed  Google Scholar 

  126. Urry, D.W., Venkatachalam, C.M., Spisni, A., Bradley, R.J., Trapane, T.L., Prasad, K.U. 1980.J. Membrane Biol. 55:29–51

    Google Scholar 

  127. Woodbury, J.W. 1971.In: Chemical Dynamics: Papers in Honor of Henry Eyring. J.O. Hirschfelder, editor. pp. 601–661. Wiley, New York

    Google Scholar 

  128. Woodhull, A.M. 1973.J. Gen. Physiol. 61:687–708

    Google Scholar 

  129. Zwolinsky, B.J., Eyring, H., Reese, C.E. 1949.J. Physiol. Colloid Chem. 53:1426–1453

    Google Scholar 

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    George Eisenman & Richard Horn

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Eisenman, G., Horn, R. Ionic selectivity revisited: The role of kinetic and equilibrium processes in ion permeation through channels. J. Membrain Biol. 76, 197–225 (1983). https://doi.org/10.1007/BF01870364

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