Summary
The antibiotic properties of 2 acidic C24H40O4 nor-sesterterpenoid peroxides, prianicin A (1) and B (2), against gram-positive and gram-negative bacteria, and against fungi are herein described. They are 4–10 times more effective than tetracycline againstbeta hemolytic Streptococcus, but significantly non-effective against a variety of gram-negative bacteria.
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Acknowledgment. The authors are grateful to Prof. A. Kjaer of the Organic Chemistry Department of the Technical University of Denmark, for his help and fruitful discussions.
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Sokoloff, S., Halevy, S., Usieli, V. et al. Prianicin A and B, nor-sesterterpenoid peroxide antibiotics from red sea sponges. Experientia 38, 337–338 (1982). https://doi.org/10.1007/BF01949377
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DOI: https://doi.org/10.1007/BF01949377