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Codon reassignment (codon capture) in evolution

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Summary

The genetic code, once thought to be “frozen”, show variations from the universal code. Variations are found in mitochondria,Mycoplasma, and ciliated protozoa. The variations results from reassignment of codons, especially stop codons. The ressignments take place by disappearance of a codon from coding sequences, followed by its reappearance in a new role. Simultaneously, a changed anticodon must appear. We discuss the role of directional mutation pressure in the pressure in the events, and we also describe the possibility that such events have taken place during early evolution of the genetic code and can occur during its present evolution.

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Authors and Affiliations

  1. Laboratory of Molecular Genetics, Department of Biology, Nagoya University, 464, Nagoya, Japan

    Syozo Osawa

  2. Space Sciences Laboratory, University of California, 94720, Berkeley, California, USA

    Thomas H. Jukes

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  1. Syozo Osawa
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  2. Thomas H. Jukes
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Osawa, S., Jukes, T.H. Codon reassignment (codon capture) in evolution. J Mol Evol 28, 271–278 (1989). https://doi.org/10.1007/BF02103422

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  • DOI: https://doi.org/10.1007/BF02103422

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