Abstract
With the aim of developing an ideal bone graft, a new bone grafting material was developed using deglued bone, chitosan and gelatin. Deglued bone (DGB) which is a by-product of bone glue industries and has the close crystallographic similarities of hydroxyapatite was used as main component in the preparation of bone implant. Chitosan was prepared from the exoskeleton of prawn (Pinaeus indicus, family Crustaceae) which is a by-product of seafood industries. Chitosan gives toughness to the product and do not allow the DGB particles to wither away when the implant is placed in the defect. Gelatin was used as binder for the preparation of DGB-chitosan composite. The DGB, chitosan and DGB-chitosan-gelatin composite, which were prepared in the laboratory, were analysed for their physicochemical properties by infrared spectroscopy, X-ray diffraction and scanning electron microscopy studies.
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References
Cooke F W 1992Clin. Ortho. Rel. Res. 27 135
Jianguo Li, Haihong Liao and Malena S 1997Biomaterials 18 743
Mochizuki A, Sato V, Ogawara H and Vamashita S 1989J. Appl. Polym. Sci. 37 3375
Onishi H and Machida Y 1999Biomaterials 20 175
Okuyama K, Noguchi K, Hanafusa Y, Osawa K and Ogawa K 1999Int. J. Biol. Macromol. 26 285
Stefano Guizzardi 2000J. Biomed. Mater. Res. 53 227
Sinha R N, Varma D K and Madan P 1972J. Plastic and Reconstructive Surgery 5 56
Tucker B E, Cottel C M, Auyering R C V, Spector M and Nicollas G H 1996Biomaterials 17 631
Uchida A, Araki N, Shinto Y, Yoshikawa H, Ono K and Kurisaki E 1990J. Bone Joint Surgery 72-B 298
Varma H K, Yokogawa Y, Espinosa F F, Kawamoto Y, Nishizawa K, Nagata F and Kameyama T 1999Biomaterials 20 879
Wafaa I A F, Oscris W G, Shamael S M and Khalil M R 1994Biomaterials 15 609
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Saraswathy, G., Pal, S., Rose, C. et al. A novel bio-inorganic bone implant containing deglued bone, chitosan and gelatin. Bull Mater Sci 24, 415–420 (2001). https://doi.org/10.1007/BF02708641
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DOI: https://doi.org/10.1007/BF02708641