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SCRAM: A scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes

Part I: Structure of the scoring and ranking systemPart II: Bioaccumulation potential and persistencePart III: Acute and subchronic or chronic toxicityPart IV: Results from representative chemicals, sensitivity analysis, and discriminatory power

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Abstract

The Chemical Scoring and Ranking Assessment Model (SCRAM) has been described in Parts I–III of this series (Snyder et al., 1999a; 1999b; 1999c). SCRAM is a chemical scoring and ranking (CSR) system that scores chemicals on the basis of bioaccumulation potential, environmental persistence, and toxicity. Part IV describes various tests and descriptions of the performance of this system. A group of 21 representative chemicals was chosen and scored to test the system. For those chemicals, the percentages of the scores associated with fate-related properties and associated with data uncertainty were determined. The scoring of four of these chemicals is described in greater detail, and the suitability of the scores is discussed. An analysis of the sensitivity of the system to incomplete data sets is presented. And finally, the discriminatory power of the system is described.

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References

  • IJC (1989): Standard methods for the compilation and maintenance of lists of substances of concern for the objectives development consideration under the Great Lakes Water Quality Agreement (1987) Protocol; Submission to the parties. International Joint Commission, November 30

  • Snyder, E.M.; Snyder, S.A.; Giesy, J.P. Blonde, S.A.; Hurlburt, G.K.; Summer, C.L.; Mitchell, R.R.; Bush, D.M. (1999a): SCRAM: A scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes. Part I. Structure of the scoring and ranking system. ESPR -Environ. Sci. & Pollut. Res. Online Publication (Online First): October 29th, 1999. Print Publication: ESPR7 (1) 2000

  • Snyder, E.M.; Snyder, S.A.; Giesy, J.P.; Blonde, S.A.; Hurlburt, G.K.; Summer, C.L.; Mitchell, R.R.; Bush, D.M. (1999b): SCRAM: A scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes. Part II. Bioaccumulation potential and persistence. Acute and subchronic or chronic toxicity. ESPR — Environ. Sci.& Pollut. Res. Online Publication (Online First): October 29th, 1999. Print Publication: ESPR7 (3) 2000

  • Snyder, E.M.; Snyder, S.A.; Giesy, J.R; Blonde, S.A.; Hurlburt, G.K.; Summer, C.L.; Mitchell, R.R.; Bush, D.M. (1999c): SCRAM: A scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes. Part III. Acute and subchronic or chronic toxicity. ESPR — Environ. Sci. & Pollut. Res. Online Publication (Online First): October 29th, 1999. Print Publication: ESPR7 (3) 2000

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Authors and Affiliations

  1. Dept. of Zoology, Michigan State University, National Food Safety and Toxicology Center and Institute of Environmental Toxicology, 48824, East Lansing, MI, USA

    Erin M. Snyder, Shane A. Snyder & John P. Giesy

  2. Michigan Dept. of Environmental Quality, Surface Water Quality Division, PO Box 30273, 48909-7773, Lansing, MI, USA

    Shari A. Blonde, Gary K. Hurlburt, Cheryl L. Summer, Rachel R. Mitchell & Dennis M. Bush

Authors
  1. Erin M. Snyder
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  2. Shane A. Snyder
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  3. John P. Giesy
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  4. Shari A. Blonde
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  5. Gary K. Hurlburt
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  6. Cheryl L. Summer
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  7. Rachel R. Mitchell
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  8. Dennis M. Bush
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Additional information

Deceased

The scoring and ranking system in the form of a Lotus 123197 spreadsheet and a description of its use are available on the Internet athttp://www.epa.gov/toxteam/pbtrept/

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Snyder, E.M., Snyder, S.A., Giesy, J.P. et al. SCRAM: A scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes. Environ. Sci. & Pollut. Res. 7, 220–224 (2000). https://doi.org/10.1007/BF02987352

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  • DOI: https://doi.org/10.1007/BF02987352

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