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Electrochemical sensing with electrodes modified with molecularly imprinted polymer films

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Abstract

This article summarises our work on the development of voltammetric sensors based on molecularly imprinted polymers. Several recognition elements and integration strategies were used:

  1. 1.

    membranes electropolymerised at the electrode surface;

  2. 2.

    casting of polymeric membranes by drop-coating a solution of pre-formed polymer (polyphosphazene) and template in a low-boiling-point solvent on to the electrode surface;

  3. 3.

    preparation of composite membranes containing conductive material (graphite or carbon black), acrylic-type molecularly imprinted polymers (small particle size), and PVC as binder; and

  4. 4.

    in-situ polymerisation of a thin layer of acrylic imprinted polymer deposited on the electrode surface by spin coating.

All the options evaluated offer the possibility of controlling electrode characteristics such as hydrophobic/hydrophilic character, permeability, or film thickness, which are essential for obtaining good sensor performance.

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Acknowledgements

Financial support from the Spanish government (Ministerio de Ciencia y Tecnología, project No. BQ-2002–00261) is acknowledged. S. Gutiérrez-Fernández thanks FICYT for a grant.

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Authors and Affiliations

  1. Departamento de Química Física y Analítica, Facultad de Química, Universidad de Oviedo, C/Julián Clavería 8, 33006, Oviedo, Spain

    M. C. Blanco-López, S. Gutiérrez-Fernández, M. J. Lobo-Castañón, A. J. Miranda-Ordieres & P. Tuñón-Blanco

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  1. M. C. Blanco-López
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  2. S. Gutiérrez-Fernández
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  3. M. J. Lobo-Castañón
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  5. P. Tuñón-Blanco
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Correspondence to P. Tuñón-Blanco.

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Blanco-López, M.C., Gutiérrez-Fernández, S., Lobo-Castañón, M.J. et al. Electrochemical sensing with electrodes modified with molecularly imprinted polymer films. Anal Bioanal Chem 378, 1922–1928 (2004). https://doi.org/10.1007/s00216-003-2330-2

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  • DOI: https://doi.org/10.1007/s00216-003-2330-2

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