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Rapid bioanalysis with chemical sensors: novel strategies for devices and artificial recognition membranes

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Abstract

The increasing importance of biological analytes in chemistry has triggered the development of a vast number of techniques for rapidly assessing them. Aside from microbiological test methods, a wide range of analytical sensor and detection methods are being developed. Within this article, we review the literature on this topic from the last five years, stressing two main aspects of method development. The first aspect is the design of novel analytical strategies and transducers to generate signals more sensitively, more rapidly and more efficiently. Most of the progress in this field has focused on electrochemical detection, although novel approaches to optical and mass-sensitive measurements have been reported. Second, we provide an overview of two main approaches to creating artificial interaction layers for sensors based on tailored interaction sites in polymeric or biomimetic systems. The most prominent of these approaches is (molecular) imprinting, where selectivity is achieved by directly templating a polymer material with the target analyte or a model compound, thus achieving biomimetic interaction sites within both thin films and particles.

Sensors as means for rapid analysis gain increasing interest and importance in bioanalyte sensing. This article reviews recent developments in the design of transducers and artificial recognition membranes for assessing different biological species.

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References

  1. Sheehan AD, Quinn J, Daly S, Dillon P, O’Kennedy R (2003) Anal Lett 36:511–537

    Article  CAS  Google Scholar 

  2. Yi C, Li CW, Ji S, Yang M (2006) Anal Chim Acta 560:1–23

    Article  CAS  Google Scholar 

  3. Pickup JC, Hussain F, Evans ND, Rolinski OJ, Birch DJS (2005) Biosens Bioelectron 20:2555–2565

    Article  CAS  Google Scholar 

  4. Trojanowicz M, Wcislo M (2005) Anal Lett 38:523–547

    CAS  Google Scholar 

  5. Willner I, Baron R, Willner B (2007) Biosens Bioelectron 22:1841–1852

    Article  CAS  Google Scholar 

  6. Nagl S, Wolfbeis OS (2007) Analyst 132:507–511

    Article  CAS  Google Scholar 

  7. Bossi A, Bonini F, Turner APF, Piletsky SA (2007) Biosens Bioelectron 22:1131–1137

    Article  CAS  Google Scholar 

  8. Cooper MA (2003) Anal Bioanal Chem 377:834–842

    Article  CAS  Google Scholar 

  9. Hassan SSM, Elnemma EM, Mohamed AHK (2005) Electroanalysis 17:2246–2253

    Article  CAS  Google Scholar 

  10. Yang L, Li Y, Griffis C, Johnson MG (2004) Biosens Bioelectron 19:1139–1147

    Article  CAS  Google Scholar 

  11. White SF, Tothill IE, Newman JD, Turner APF (1996) Anal Chim Acta 321:165–172

    Article  CAS  Google Scholar 

  12. Maestre E, Katakis I, Narváez A, Domínguez E (2005) Biosens Bioelectron 21:774–781

    Article  CAS  Google Scholar 

  13. Popovtzer R, Neufeld T, Ron EZ, Rishpon J, Shacham-Diamand Y (2006) Sens Actuators B 119:664–672

    Article  Google Scholar 

  14. Satake D, Ebi H, Oku N, Matsuda K, Takao H, Ashiki M, Ishida M (2002) Sens Actuators B 83:77–81

    Article  Google Scholar 

  15. Katz E, Willner I (2004) Ultrathin electrochemical chemo- and biosensors (Springer Series on Chemical Sensors and Biosensors, vol 2). Springer, Berlin, pp 67–116

  16. Katz E, Willner I (2003) Electronanalysis 15:913–947

    Article  CAS  Google Scholar 

  17. Campbell CE, Laane MM, Haugarvoll E, Giaevar I (2007) Biosens Bioelectron 23:536–542

    Article  CAS  Google Scholar 

  18. McCoy MH, Wang E (2005) J Virol Methods 130:157–161

    Article  CAS  Google Scholar 

  19. Luong JHT (2003) Anal Lett 36:3147–3164

    Article  CAS  Google Scholar 

  20. Ding L, Hao C, Xue Y, Ju H (2007) Biomacromolecules 8:1341–1346

    Article  CAS  Google Scholar 

  21. Steinem C, Janshoff A (eds)(2007) Piezoelectric sensors (Springer Series on Chemical Sensors and Biosensors, vol 5). Springer, Berlin

  22. Chang KS, Chang CK, Chen CY (2007) Sens Actuators B 125:207–213

    Article  Google Scholar 

  23. Zhu Q, Shih WY, Shih WH (2007) Sens Actuators B 125:379–388

    Article  Google Scholar 

  24. McGovern JP, Shih WY, Shih WH (2007) Analyst 132:777–783

    Article  CAS  Google Scholar 

  25. Campbell GA, Mutharasan R (2005) Biosens Bioelectron 21:597–607

    Article  CAS  Google Scholar 

  26. Hyun SJ, Kim HS, Kim YJ, Jung HI (2006) Sens Actuators B 117:415–419

    Article  Google Scholar 

  27. Miranda OR, You CC, Phillips R, Kim IB, Ghosh PS, Bunz UHF, Rotello VM (2007) J Am Chem Soc 32:9856–9857

    Article  Google Scholar 

  28. Previte MJR, Geddes CD (2007) J Am Chem Soc 129:9850–9851

    Article  CAS  Google Scholar 

  29. Previte MJR, Aslan K, Malyn SN, Geddes CD (2006) Anal Chem 78:8020–8027

    Article  CAS  Google Scholar 

  30. Homola J (ed)(2006) Surface plasmon resonance based sensors (Springer Series on Chemical Sensors and Biosensors, vol 4). Springer, Berlin

  31. Scott PK, Cheng Q (2007) Anal Bioanal Chem 387:1831–1840

    Article  Google Scholar 

  32. Yu X, Wang D, Wei X, Ding X, Liao W, Zhao X (2005) Sens Actuators B 108:765–771

    Article  Google Scholar 

  33. Knopp D (2006) Anal Bioanal Chem 385:425–427

    Article  CAS  Google Scholar 

  34. González-Martínez MA, Puchades R, Maquieira A (2007) Anal Bioanal Chem 387:205–218

    Article  Google Scholar 

  35. Kurosawa S, Park JW, Aizawa H, Wakida SI, Tao H, Ishihara K (2006) Biosens Bioelectron 22:473–481

    Article  CAS  Google Scholar 

  36. Cosnier S (2007) Anal Lett 40:1260–1279

    Article  CAS  Google Scholar 

  37. Muguruma H (2007) TrAC 26:433–443

    CAS  Google Scholar 

  38. Gupta R, Chaudhury NK (2007) Biosens Bioelectron 22:2387–2399

    Article  CAS  Google Scholar 

  39. Pumera M, Sánchez S, Ichinose I, Tang J (2007) Sens Actuators B 123:1195–1205

    Article  Google Scholar 

  40. Vadgama P (2007) Analyst 132:495–499

    Article  CAS  Google Scholar 

  41. Komarova E, Aldissi M, Bogomolova A (2005) Biosens Bioelectron 21:182–189

    Article  CAS  Google Scholar 

  42. Rick J, Chou TC (2006) Biosens Bioelectron 22:329–335

    Article  CAS  Google Scholar 

  43. Zadmard R, Schrader T (2005) J Am Chem Soc 127:904–915

    Article  CAS  Google Scholar 

  44. Delaney TL, Zimin D, Rahm M, Weiss D, Wolfbeis OS, Mirsky V (2007) Anal Chem 79:3220–3225

    Article  CAS  Google Scholar 

  45. Bacskay I, Takátsy A, Végváry A, Elfwing A, Ballagi-Pordány A, Kilar F, Hjertén S (2006) Electrophoresis 27:4682–4687

    Article  CAS  Google Scholar 

  46. Hayden O, Mann KJ, Krassnig S, Dickert FL (2006) Angew Chem Int Ed 45:2626–2629

    Article  CAS  Google Scholar 

  47. Hayden O, Podlipna D, Chen X, Krassnig S, Leidl A, Dickert FL (2006) Mater Sci Eng C 26:924–928

    Google Scholar 

  48. Bereczki A, Tolokán A, Horvai G, Horvath V, Lanza F, Hall AJ, Sellergren B (2001) J Chromatogr A 930:31–38

    Google Scholar 

  49. Lotierzo M, Henry OYF, Piletsky S, Tothill I, Cullen D, Kania M, Hock B, Turner APF (2004) Biosens Bioelectron 20:145–152

    Article  CAS  Google Scholar 

  50. Boonpangrak S, Whitcombe MJ, Prachayasittikul V, Mosbach K, Ye L (2006) Biosens Bioelectron 22:349–354

    Article  CAS  Google Scholar 

  51. Kitade T, Kitamura K, Konishi T, Takegami S, Okuno T, Ishikawa M, Wakabayashi M, Nishikawa K, Muramatsu Y (2004) Anal Chem 76:6802–6807

    Article  CAS  Google Scholar 

  52. Wang HJ, Zhou WH, Yin XF, Zhuang ZX, Yang HH, Wang XR (2006) J Am Chem Soc 128:15954–15955

    Article  CAS  Google Scholar 

  53. Hayden O, Haderspöck C, Krassnig S, Chen X, Dickert FL (2006) Analyst 131:1044–1051

    Article  CAS  Google Scholar 

  54. Rick J, Chou TC (2005) Anal Chim Acta 542:26–31

    Article  CAS  Google Scholar 

  55. Bonini F, Piletsky S, Turner APF, Speghini A, Bossi A (2007) Biosens Bioelectron 22:2322–2328

    Article  CAS  Google Scholar 

  56. Stephenson CJ, Carroll WR, Yehl MA, Shimizu KD (2006) Polym Prepr 47:463

    CAS  Google Scholar 

  57. Dickert FL, Hayden O, Bindeus R, Mann KJ, Blaas D, Waigmann E (2004) Anal Bioanal Chem 378:1929–1934

    Article  CAS  Google Scholar 

  58. Hayden O, Lieberzeit PA, Blaas D, Dickert FL (2006) Adv Funct Mater 16:1269–1278

    Article  CAS  Google Scholar 

  59. Bolisay LD, Culver JN, Kofinas P (2006) Biomater 27:4165–4168

    Article  CAS  Google Scholar 

  60. Lieberzeit PA, Gazda-Miarecka S, Halikias K, Schirk C, Kauling J, Dickert FL (2005) Sens Actuators B 111–112:259–263

    Article  Google Scholar 

  61. Harvey SD, Mong GM, Ozanich RM, Mclean JS, Goodwin SM, Valentine NB, Fredrickson JK (2006) Anal Bioanal Chem 386:211–219

    Article  CAS  Google Scholar 

  62. Lieberzeit PA, Afzal A, Podlipna D, Krassnig S, Blumenstock H, Dickert FL (2007) Sens Actuators B 126:153–158

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Analytical Chemistry and Food Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria

    Peter A. Lieberzeit & Franz L. Dickert

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  1. Peter A. Lieberzeit
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  2. Franz L. Dickert
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Correspondence to Franz L. Dickert.

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Lieberzeit, P.A., Dickert, F.L. Rapid bioanalysis with chemical sensors: novel strategies for devices and artificial recognition membranes. Anal Bioanal Chem 391, 1629–1639 (2008). https://doi.org/10.1007/s00216-008-1909-z

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  • DOI: https://doi.org/10.1007/s00216-008-1909-z

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