Abstract
We studied alpha and beta EEG oscillatory changes in healthy volunteers during two different auditory go/no-go paradigms, in order to investigate their relationship with different components of the motor process. In the first paradigm (S2-centered), the initial tone (S1) was constant (warning), and the second tone (S2) indicated the subject whether to move or not. In the second paradigm (S1-centered), S1 indicated whether to move or not, while S2 just indicated the timing of the movement. A medial frontal beta energy increase was found in all conditions after the stimulus that forces the subject to decide whether to move or not (S1 or S2 depending on the paradigm). In both go conditions, a central alpha and beta energy decrease began after the go decision, reaching minimum values during the movement; it was followed by a beta post-movement increase, limited to the central contralateral area. In the no-go conditions, a marked fronto-central beta synchronization appeared after the decision not to move. In conclusion, our study was able to dissociate the beta oscillatory changes related to movement preparation and execution (central decrease/increase) from those associated with decision-making (medial frontal increase) and motor inhibition (fronto-central increase).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Alegre M, Gurtubay IG, Labarga A, Iriarte J, Malanda A, Artieda J (2003a) Alpha and beta oscillatory changes during stimulus-induced movement paradigms: effect of stimulus predictability. Neuroreport 14:381–385
Alegre M, Labarga A, Gurtubay IG, Iriarte J, Malanda A, Artieda J (2003b) Movement-related changes in cortical oscillatory activity in ballistic, sustained and negative movements. Exp Brain Res 148:17–25
Bokura H, Yamaguchi S, Kobayashi S (2001) Electrophysiological correlates for response inhibition in a Go/NoGo task. Clin Neurophysiol 112:2224–2232
Chatrian GE, Petersen MC, Lazarte JA (1959) The blocking of the rolandic wicket rhythm and some central changes related to movement. Electroencephalogr Clin Neurophysiol 11:497–510
Cohen JD, Perlstein WM, Braver TS, Nystrom LE, Noll DC, Jonides J, Smith EE (1997) Temporal dynamics of brain activation during a working memory task. Nature 386:604–608
Cohen L (1989) Time-frequency distributions. A review. Proc IEEE 77:941–981
Derambure P, Defebvre L, Bourriez JL, Cassim F, Guieu JD (1999) Desynchronisation et synchronisation liées a l’évènement. Etude de la réactivité des rythmes électrocorticaux en relation avec la planification et l’exécution du mouvement volontaire. Neurophysiol Clin 29:53–70
Fallgatter AJ, Bartsch AJ, Herrmann MJ (2002) Electrophysiological measurements of anterior cingulate function. J Neural Transm 109:977–988
Filipovic SR, Jahanshahi M, Rothwell JC (1999) Cortical potentials related to decision-making: comparison of two types of go/no-go decision. Neuroreport 10:3583–3587
Filipovic SR, Jahanshahi M, Rothwell JC (2000) Cortical potentials related to the nogo decision. Exp Brain Res 132:411–415
Filipovic SR, Jahanshahi M, Rothwell JC (2001) Uncoupling of contingent negative variation and alpha band event-related desynchronization in a go/no-go task. Clin Neurophysiol 112:1307–1315
Gurtubay IG, Alegre M, Labarga A, Malanda A, Iriarte J, Artieda J (2001) Gamma band activity in an auditory oddball paradigm studied with the Wavelet Transform. Clin Neurophysiol 112:1219–1228
Ikeda A, Luders HO, Collura TF, Burgess RC, Morris HH, Hamano T, Shibasaki H (1996) Subdural potentials at orbitofrontal and mesial prefrontal areas accompanying anticipation and decision making in humans: a comparison with Bereitschaftspotential. Electroencephalogr Clin Neurophysiol 98:206–212
Jasper HH (1958) Report of the Committee on Methods of Clinical Examination in Electroencephalography. Electroencephalogr Clin Neurophysiol 10:370–375
Konishi S, Nakajima K, Uchida I, Sekihara K, Miyashita Y (1998) No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging. Eur J Neurosci 10:1209–1213
Konishi S, Nakajima K, Uchida I, Kikyo H, Kameyama M, Miyashita Y (1999) Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI. Brain 122:981–991
Lai C, Ikeda A, Terada K, Nagamine T, Honda M, Xu X, Yoshimura N, Howng S, Barrett G, Shibasaki H (1997) Event-related potentials associated with judgment: comparison of S1- and S2-choice conditions in a contingent negative variation (CNV) paradigm. J Clin Neurophysiol 14:394–405
Leocani L, Toro C, Zhuang P, Gerloff C, Hallett M (2001) Event-related desynchronization in reaction time paradigms: a comparison with event-related potentials and corticospinal excitability. Clin Neurophysiol 112:923–930
Liddle PF, Kiehl KA, Smith AM (2001) Event-related fMRI study of response inhibition. Hum Brain Mapp 12:100–109
Magnani G, Cursi M, Leocani L, Volonte MA, Locatelli T, Elia A, Comi G (1998) Event-related desynchronization to contingent negative variation and self-paced movement paradigms in Parkinson’s disease. Mov Disord 13:653–660
Petrides M, Alivisatos B, Meyer E, Evans AC (1993) Functional activation of the human frontal cortex during the performance of verbal working memory tasks. Proc Natl Acad Sci USA 90:878–882
Pfurtscheller G (1981) Central beta rhythm during sensorimotor activities in man. Electroencephalogr Clin Neurophysiol 51:253–264
Pfurtscheller G, Stancak A, Neuper C (1996) Post-movement beta synchronization. A correlate of an idling motor area? Electroencephalogr Clin Neurophysiol 98:281–293
Pfurtscheller G, Stancak A, Edlinger G (1997) On the existence of different types of central beta rhythms below 30 Hz. Electroencephalogr Clin Neurophysiol 102:316–325
Salmon E, Van der Linden M, Collette F, Delfiore G, Maquet P, Degueldre C, Luxen A, Franck G (1996) Regional brain activity during working memory tasks. Brain 119:1617–1625
Singer W (1993) Synchronization of cortical activity and its putative role in information processing and learning. Annu Rev Physiol 55:349–374
Stancak A, Pfurtscheller G (1995) Desynchronization and recovery of beta rhythms during brisk and slow self-paced finger movements in man. Neurosci Lett 196:21–24
Tallon-Baudry C, Bertrand O, Delpuech C, Pernier J (1996) Stimulus specificity of phase-locked and non-phase-locked 40 Hz visual responses in human. J Neurosci 16:4240–4249
Tenke CE, Kayser J (2001) A convenient method for detecting electrolyte bridges in multichannel electroencephalogram and event-related potential recordings. Clin Neurophysiol 112:545–550
Acknowledgements
This study was partially funded by grants 00/0009–01 and 00/0009–02 from the Fondo de Investigación Sanitaria of the Spanish Ministerio de Sanidad y Consumo and by the “UTE Project CIMA.”
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Alegre, M., Gurtubay, I.G., Labarga, A. et al. Frontal and central oscillatory changes related to different aspects of the motor process: a study in go/no-go paradigms. Exp Brain Res 159, 14–22 (2004). https://doi.org/10.1007/s00221-004-1928-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00221-004-1928-8