Abstract
Noninvasive measurement of cardiac output (CO) and particularly stroke volume (SV) remain difficult but potentially valuable. These variables can be particularly challenging to measure in children with congenital heart disease (CHD). Impedance cardiography (IC) is a technique shown to be accurate in measuring SV in adults and in children with structurally normal hearts. The ease of use and rapidity of SV measurement using IC makes it potentially attractive for young patients with CHD. Advances in IC technology have led to more sophisticated signal-morphology IC (SMIC) devices that may further improve accuracy. We tested the accuracy of SMIC to measure SV in 21 subjects with CHD by comparing measurements with those from cardiac magnetic resonance (CMR) imaging. There was good agreement between SMIC and CMR in measurement of SV: mean difference = 1.7 ml (p = 0.47); r = 0.89. The agreement and correlation persisted when controlling for the differences in blood pressure and heart rate during the two testing methods. We conclude that SMIC is accurate at measuring SV and thus CO when compared to CMR in a variety of forms of CHD.
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Abbreviations
- D-TGA:
-
Dextro-transposition of great arteries
- PA:
-
Pulmonary atresia
- VSD:
-
Ventricular septal defect
- IAA:
-
Interrupted aortic arch
- TOF:
-
Tetralogy of Fallot
- TAP:
-
Trans-annular patch
- CoA:
-
Coarctation of Aorta
- AV:
-
Aortic valve
- AS:
-
Aortic stenosis
- TR:
-
Tricuspid regurgitation
- HCM:
-
Hypertrophic cardiomyopathy
- AI:
-
Aortic regurgitation
- PS:
-
Pulmonary valve stenosis
- ASD:
-
Atrial septal defect
- PAPVR:
-
Partial anomalous pulmonary venous return
- IVS:
-
Intact ventricular septum
- ASO:
-
Arterial switch operation
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Acknowledgments
The CTRI is partially supported by the National Institutes of Health Grant UL1TR001442. We would like to thank NeuMeDx for loaned equipment (PF-05 Lab1) during the study period.
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Ebrahim, M., Hegde, S., Printz, B. et al. Evaluation of Impedance Cardiography for Measurement of Stroke Volume in Congenital Heart Disease. Pediatr Cardiol 37, 1453–1457 (2016). https://doi.org/10.1007/s00246-016-1456-x
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DOI: https://doi.org/10.1007/s00246-016-1456-x