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Current status in biotechnological production and applications of glycolipid biosurfactants

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Abstract

Biosurfactants are natural compounds with surface activity and emulsifying properties produced by several types of microorganisms and have been considered an interesting alternative to synthetic surfactants. Glycolipids are promising biosurfactants, due to low toxicity, biodegradability, and chemical stability in different conditions and also because they have many biological activities, allowing wide applications in different fields. In this review, we addressed general information about families of glycolipids, rhamnolipids, sophorolipids, mannosylerythritol lipids, and trehalose lipids, describing their chemical and surface characteristics, recent studies using alternative substrates, and new strategies to improve of production, beyond their specificities. We focus in providing recent developments and trends in biotechnological process and medical and industrial applications.

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Acknowledgements

The authors acknowledge the funding agencies Conselho Nacional de Desenvolvimento Científico (CNPq), Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP), and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes).

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  1. Laboratory of Bioflavors and Bioactive Compounds, Department of Food Science, Faculty of Food Engineering, University of Campinas, Cidade Universitária “Zeferino Vaz” Barão Geraldo – Campinas, São Paulo, CEP 13083-862, Brazil

    Bruno Nicolau Paulino, Marina Gabriel Pessôa, Mario Cezar Rodrigues Mano, Iramaia Angélica Neri-Numa & Glaucia Maria Pastore

  2. Institute of Science and Technology, Food Engineering, UFVJM, Diamantina, Minas Gerais, Brazil

    Gustavo Molina

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  1. Bruno Nicolau Paulino
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  2. Marina Gabriel Pessôa
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  3. Mario Cezar Rodrigues Mano
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  4. Gustavo Molina
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  5. Iramaia Angélica Neri-Numa
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  6. Glaucia Maria Pastore
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Correspondence to Bruno Nicolau Paulino.

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Paulino, B.N., Pessôa, M.G., Mano, M.C.R. et al. Current status in biotechnological production and applications of glycolipid biosurfactants. Appl Microbiol Biotechnol 100, 10265–10293 (2016). https://doi.org/10.1007/s00253-016-7980-z

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  • DOI: https://doi.org/10.1007/s00253-016-7980-z

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