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Augmentation in anterior cruciate ligament reconstruction—a histological and biomechanical study on goats

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Abstract

We studied reconstruction of the anterior cruciate ligament (ACL) in skeletally mature goats. In one group, the autogenous tissue was augmented with polydioxanone (PDS), the other group had no augmentation. Histological complete incorporation and remodeling of the transplant was found in both groups. The newly formed connective tissues gradually assumed the microscopic properties of the normal ligament. The augmented group showed a delay in remodeling and maturation of the fiber bundles. Mechanically, the PDS-augmented transplants were stronger than the nonaugmented transplants immediately after surgery. During the first 6 weeks, a rapid decrease in strength of the augmented transplants was found, whereas the strength of the nonaugmented group gradually increased. The results of our experiment do not favor augmentation of autografts in reconstruction of the ACL.

Résumé

Nous avons étudié la reconstruction du ligament croisé antérieur chez la chèvre à squelette mature. Dans un groupe le tissu autogène a été renforcé avec du polydioxanone (PDS), l’autre groupe n’avait aucun renforcement. Une incorporation histologique complète et un remodelage du transplant a été constaté. Les tissus conjonctifs récemment formés ont pris progressivement les propriétés microscopiques du ligament normal. Le groupe renforcé a montré un délai dans le remodelage et la maturation des faisceaux de fibres. Mécaniquement les greffes renforcées au PDS étaient plus fortes que les greffes non renforcées immédiatement après la chirurgie. Pendant les six premières semaines une baisse rapide de la force des greffes renforcées a été constatée, alors que la force du groupe non—renforcé a augmenté progressivement. Les résultats de notre expérience ne sont pas en faveur d’un renforcement des autogreffes dans la reconstruction du ligament croisé antérieur.

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Authors and Affiliations

  1. Orthopaedic Research Laboratory, Institute of Orthopaedics, UMCN, PO Box 9101, 6500 HB, Nijmegen, The Netherlands

    P. Buma, L. Blankevoort, R. Huiskes & A. van Kampen

  2. Medical Center, Leeuwarden, The Netherlands

    H. J. Kok

  3. ENT, UMCN, Nijmegen, The Netherlands

    W. Kuijpers

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  1. P. Buma
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  2. H. J. Kok
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  3. L. Blankevoort
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  4. W. Kuijpers
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  5. R. Huiskes
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  6. A. van Kampen
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Correspondence to P. Buma.

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Buma, P., Kok, H.J., Blankevoort, L. et al. Augmentation in anterior cruciate ligament reconstruction—a histological and biomechanical study on goats. International Orthopaedics (SICOT) 28, 91–96 (2004). https://doi.org/10.1007/s00264-003-0515-0

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  • DOI: https://doi.org/10.1007/s00264-003-0515-0

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