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Nanoscale Powders and Formulations with Biocidal Activity Toward Spores and Vegetative Cells of Bacillus Species, Viruses, and Toxins

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Abstract

Certain formulations of nanoscale powders possess antimicrobial properties. These formulations are made of simple, nontoxic metal oxides such as magnesium oxide (MgO) and calcium oxide (CaO, lime) in nanocrystalline form, carrying active forms of halogens, for example, MgO · Cl2 and MgO · Br2. When these ultrafine powders contact vegetative cells of Escherichia coli, Bacillus cereus, or Bacillus globigii, over 90% are killed within a few minutes. Likewise, spore forms of the Bacillus species are decontaminated within several hours. Dry contact with aflatoxins and contact with MS2 bacteriophage (surrogate of human enterovirus) in water also causes decontamination in minutes.

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Authors and Affiliations

  1. Nanoscale Material, Inc. (formerly Nantek, Inc.), 1500 Hays Drive, Manhattan, KS 66502, USA, , , , , , US

    Olga B. Koper & John S. Klabunde

  2. Department of Chemistry, Kansas State University, Manhattan, KS 66506, USA, , , , , , US

    Kenneth J. Klabunde & Peter Stoimenov

  3. Division of Biology, Kansas State University, Manhattan, KS 66506, USA, , , , , , US

    George L. Marchin

  4. Food Labs, 1500 Hayes Drive, Manhattan, KS 66502, USA, , , , , , US

    Lalit Bohra

Authors
  1. Olga B. Koper
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  2. John S. Klabunde
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  3. George L. Marchin
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  4. Kenneth J. Klabunde
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  5. Peter Stoimenov
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  6. Lalit Bohra
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Received: 10 April 2001 / Accepted: 14 May 2001

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Koper, O., Klabunde, J., Marchin, G. et al. Nanoscale Powders and Formulations with Biocidal Activity Toward Spores and Vegetative Cells of Bacillus Species, Viruses, and Toxins. Curr Microbiol 44, 49–55 (2002). https://doi.org/10.1007/s00284-001-0073-x

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  • DOI: https://doi.org/10.1007/s00284-001-0073-x

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