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Research on the glucose-sensing characteristics of gold microparticle-doped silica microfiber based on refractive index measurement

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Abstract

A gold microparticle-doped silica microfiber was proposed in this paper. The refractive index sensing properties were experimentally and calculatedly demonstrated by transmission spectra using glucose solution with different concentrations, where the redshift of resonance peaks has been analyzed for the concentrations range from 0 to 0.282 mol/L. The experimental results indicate the detection limit of 53.2 μmol/L. The sensing characteristics of pure silica microfiber were experimentally and calculatedly explored to demonstrate the impact of the gold particles introduction on the sensitivity enhancement. The miniature geometry will prompt the development of the novel wearable or implantable glucose sensor.

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References

  1. D. Ganziy, O. Jespersen, G. Woyessa, B. Rose, O. Bang, Dynamic gate algorithm for multimode fiber Bragg grating sensor systems. Appl. Opt. 54, 5657 (2015)

    Article  ADS  Google Scholar 

  2. Y. Zhao, X.G. Li, L. Cai, A highly sensitive Mach-Zehnder interferometric refractive index sensor based on core-offset single mode fiber. Sens. Actuators A-Phys. 223, 119 (2015)

    Article  Google Scholar 

  3. S.M. Weiss, G. Rong, J.L. Lawrie, Current status and outlook for silicon-based optical biosensors. Phys. E 41, 1071–1075 (2009)

    Article  Google Scholar 

  4. P. Zu, C.C. Chan, T.X. Gong, Y.X. Jin, W.C. Wong, X.Y. Dong, Magneto-optical fiber sensor based on bandgap effect of photonic crystal fiber infiltrated with magnetic fluid. Appl. Phys. Lett. 101, 241118 (2012)

    Article  ADS  Google Scholar 

  5. K. Milenko, D.J.J. Hu, P.P. Shum, T.S. Zhang, J.L. Lim, Y.X. Wang, T.R. Wolinski, H.F. Wei, W.J. Tong, Photonic crystal fiber tip interferometer for refractive index sensing. Opt. Lett. 37, 1373 (2012)

    Article  ADS  Google Scholar 

  6. V. Dillu, T. Srivastava, R.K. Sinha, Propagation characteristics of silver nanorods based compact waveguides for plasmonic circuitry. Phys. E 48, 75–79 (2013)

    Article  Google Scholar 

  7. W.B. Ji, H.H. Liu, S.C. Tjin, K.K. Chow, A. Lim, Ultrahigh sensitivity refractive index sensor based on optical microfiber. IEEE Photonic Technol. Lett. 24, 1872 (2012)

    Article  ADS  Google Scholar 

  8. F.J. Li, J. Zhang, Spectral characteristics of polymer micro-fiber MZI near 1550 nm. Phys. E 63, 131–133 (2014)

    Article  Google Scholar 

  9. Y. Wang, D.N. Wang, C.R. Liao, T.Y. Hu, J.T. Guo, H.F. Wei, Temperature-insensitive refractive index sensing by use of micro Fabry-Perot cavity based on simplified hollow-core photonic crystal fiber. Opt. Lett. 38, 269 (2013)

    Article  ADS  Google Scholar 

  10. Y. Zhao, Z.Q. Deng, Q. Wang, Fiber optic SPR sensor for liquid concentration measurement. Sens. Actuators. B-Chem. 192, 229 (2014)

    Article  Google Scholar 

  11. F. Tian, Z.H. He, H. Du, Numerical and experimental investigation of long-period gratings in photonic crystal fiber for refractive index sensing of gas media. Opt. Lett. 37, 380 (2012)

    Article  ADS  Google Scholar 

  12. Y.Q. Zhang, Y.Z. Wang, J.B. Jia, J.G. Wang, Nonenzymatic glucose sensor based on graphene oxide and electrospun NiO nanofibers. Sens. Actuators. B-Chem. 171, 580 (2012)

    Article  Google Scholar 

  13. M.M. Liu, R. Liu, W. Chen, Graphene wrapped Cu2O nanocubes: non-enzymatic electrochemical sensors for the detection of glucose and hydrogen peroxide with enhanced stability. Biosens. Bioelectron. 45, 206 (2013)

    Article  Google Scholar 

  14. B.B. Luo, Z.J. Yan, Z.Y. Sun, J.F. Li, L. Zhang, Novel glucose sensor based on enzymeimmobilized 81° tilted fiber grating. Opt. Express 22, 30571 (2014)

    Article  ADS  Google Scholar 

  15. W. Zhang, W.X. Ye, C. Wang, W.B. Li, Z. Yue, G.H. Liu, Silver nanoparticle arrays enhanced spectral surface plasmon resonance optical sensor. Micro Nano Lett. 9, 585 (2014)

    Article  Google Scholar 

  16. C.C. Hsu, Y.C. Chen, J.Y. Lee, C.C. Wu, Reusable glucose fiber sensor for measuring glucose concentrations in serum. Chin. Opt. Lett. 9, 100608 (2011)

    Article  ADS  Google Scholar 

  17. Y. Su, X.S. Yao, Z. Meng, L.Z. Wang, H.M. Yu, T.G. Liu, Effect of temperature on noninvasive blood glucose monitoring in vivo using optical coherence tomography. Chin. Opt. Lett. 12, 111701 (2014)

    Article  ADS  Google Scholar 

  18. J. Li, H.Y. Li, K.Y. Wang, X.N. Zhang, C.B. Yao, Y.D. Zhang, P. Yuan, Plasmon resonance of silver micro-sphere in fiber taper. Opt. Express 21, 21414 (2013)

    Article  ADS  Google Scholar 

  19. J. Li, Y.D. Zhang, H.Y. Li, C.B. Yao, P. Yuan, The optical response of the silver nano-sphere with two spindle-shaped cavities in a sub-wavelength quartz fiber. Epl-Europhys. Lett. 102, 67012 (2013)

    Article  ADS  Google Scholar 

  20. W.M. Haynes, CRC handbook of chemistry and physics (CRC Press, Boca raton, 2013)

    Google Scholar 

  21. J. Wang, Electrochemical glucose biosensors. Chem. Rev. 108, 814 (2008)

    Article  Google Scholar 

Download references

Acknowledgements

The authors thank the support from National Natural Science Foundation for Young Scholars of China under Grants 61405032, 61403074 and 61605031, National Natural Science Foundation for Distinguished Young Scholars of China under Grant 61425003, Doctoral Scientific Research Startup Foundation of Liaoning Province under Grant 201501144, Fundamental Research Funds for the Central Universities under Grants N150404022 and N150401001.

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Hu, H., Li, J., Li, H. et al. Research on the glucose-sensing characteristics of gold microparticle-doped silica microfiber based on refractive index measurement. Appl. Phys. B 122, 282 (2016). https://doi.org/10.1007/s00340-016-6560-3

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