Skip to main content
SpringerLink
Log in

Production of Cyclosporin A by solid state fermentation

  • Published:
Bioprocess Engineering Aims and scope Submit manuscript

Abstract

 The production of Cyclosporin A using wheat bran as the solid substrate was attempted using Tolypocladium sp. and it was found that the yield was 10 times more than the yield obtained by submerged fermentation. Hydrolysing the wheat bran using dilute HCl was found to increase the yield. Different solvents were used for the optimization of extraction of Cyc A from the fermented bran.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Malladi Research Centre, No. 52, Jawaharlal Nehru Road, Ekkattuthangal, Madras-600 097, , , , ,

    C. Sekar & V. W. Rajasekar

  2. Vector Control Research Centre (ICMR), Pondicherry, India, , , , , , IN

    K. Balaraman

Authors
  1. C. Sekar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. W. Rajasekar
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Balaraman
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received 11 December 1996

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sekar, C., Rajasekar, V. & Balaraman, K. Production of Cyclosporin A by solid state fermentation. Bioprocess Engineering 17, 257–259 (1997). https://doi.org/10.1007/s004490050383

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004490050383

Keywords

Search

Navigation