Skip to main content
SpringerLink
Log in

Applications of nanostructured Pt-Au hybrid film for the simultaneous determination of catecholamines in the presence of ascorbic acid

  • Original Paper
  • Published:
Journal of Solid State Electrochemistry Aims and scope Submit manuscript

Abstract

Nanostructured platinum-gold (Pt–Au) hybrid film modified glassy carbon electrode (GCE) was fabricated by electro-deposition method in the presence of 2 × 10−4 mol l−1 l-cysteine. To examine the surface morphological analysis, the (Pt–Au) hybrid film were electrochemically deposited on transparent semiconductor indium tin oxide (ITO) electrodes for scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) studies. From the SEM analysis, it was observed that the deposited nanoplatinum (250–400 nm) was formed as a cauliflower-shaped structure with the gold nanoparticles (30–90 nm). The concentration variation of additive l-cysteine results in the formation of cauliflower-shaped platinum nanoparticles. Further, the Pt–Au hybrid film modified GCE could be used for the detection of catecholamine neurotransmitters epinephrine (EP), norepinephrine (NEP) individually and in the presence of ascorbic acid (AA) in pH 7 phosphate-buffered solutions (PBS). Furthermore, the proposed Pt–Au hybrid film could be applied for the detection of epinephrine in injection solution and ascorbic acid from commercially available vitamin C tablets.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Bergquist J, Sciubisz A, Kaczor A, Silberring J (2002) J Neurosci Methods 15:1

    Article  Google Scholar 

  2. Solich P, Polydorou CH, Koupparis MA (2000) J Pharm Biomed Anal 22:781

    Article  CAS  Google Scholar 

  3. Yang J, Zhang G, Wu X, Huang F, Lin C, Cao X, Sun L, Ding Y (1998) Anal Chim Acta 363:105

    Article  CAS  Google Scholar 

  4. Sabbioni C, Saracino MA, Mandrioli R, Pinzauti S, Furlanetto S, Gerra G, Raggi MA (2004) J Chromatogr A 1032:65

    Article  CAS  Google Scholar 

  5. Lin CE, Fang IJ, Deng YJ, Liao WS, Cheng HT, Huang WP (2004) J Chromatogr A 1051:85

    CAS  Google Scholar 

  6. Michalowski J, Halaburda P (2001) Talanta 55:1165

    Article  CAS  Google Scholar 

  7. Li F, Cui H, Lin XQ (2002) Anal Chim Acta 471:187

    Article  CAS  Google Scholar 

  8. Ni JA, Ju HX, Chen HY, Leech D (1999) Anal Chim Acta 378:151

    Article  CAS  Google Scholar 

  9. Mateo JVG, Kojlo A (1997) J Pharm Biomed Anal 15:1821

    Article  CAS  Google Scholar 

  10. Mo Z, Long X, Zhang M (1999) Talanta 48:643

    Article  CAS  Google Scholar 

  11. Tsai YC, Chiu CC (2007) Sens Actuators B Chem 125:10

    Article  CAS  Google Scholar 

  12. Zhu M, Huang X, Li J, Shen H (1997) Anal Chim Acta 357:261

    Article  CAS  Google Scholar 

  13. Ye BX, Xia P, Lin L (2000) Microchem J 64:125

    Article  Google Scholar 

  14. Zhang S, Xu Q, Zhang W, Jin L, Jin J-Y (2001) Anal Chim Acta 427:45

    Article  CAS  Google Scholar 

  15. Wang H, Jin H, Zhang HS (1999) J Anal Chem 365:682

    Article  CAS  Google Scholar 

  16. Guan CL, Quyang J, Li QL, Liu BH, Baeyens WR (2000) Talanta 50:1197

    Article  CAS  Google Scholar 

  17. Arya SP, Mahajan M, Jain P (2001) Anal Chim Acta 427:245

    Article  CAS  Google Scholar 

  18. Fontannaz P, Kilinc T, Heudi O (2006) Food Chem 94:626

    Article  CAS  Google Scholar 

  19. Lopes P, Drinkine J, Saucier C, Glories Y (2006) Anal Chim Acta 555:242

    Article  CAS  Google Scholar 

  20. Zhang HM, Zhou XL, Hui RT, Li NQ, Liu DP (2002) Talanta 56:1081

    Article  CAS  Google Scholar 

  21. Kawage TK, Wightman RM (1994) Talanta 41:865

    Article  Google Scholar 

  22. Luo H, Shi Z, Ni N, Gu Z, Zhuang Q (2001) Anal Chem 73:915

    Article  CAS  Google Scholar 

  23. Wang J, Li M, Shi Z, Li N, Gu Z (2002) Electroanalysis 14:225

    Article  CAS  Google Scholar 

  24. Valentini F, Amine A, Orlanducci S, Terranova ML, Palleschi G (2003) Anal Chem 75:5413

    Article  CAS  Google Scholar 

  25. Raoof JB, Ojani R, Nadimi SR (2005) Electrochim Acta 50:4694

    Article  CAS  Google Scholar 

  26. Lu LP, Wang SQ, Lin XQ (2004) Anal Chim Acta 519:161

    Article  CAS  Google Scholar 

  27. Oyama M (2007) Rev Polarogr 53:1

    Article  Google Scholar 

  28. El-Deab MS, Sotomura T, Ohsaka T (2005) J Electrochem Soc 152:C1

    Article  CAS  Google Scholar 

  29. Thiagarajan S, Chen SM (2007) Talanta 74:222

    Article  CAS  Google Scholar 

  30. Luo J, Njoki PN, Mott D, Wang L, Zhong CJ (2006) Langmuir 22:2892

    Article  CAS  Google Scholar 

  31. Luo J, Njoki PN, Mott D, Wang L Zhong CJ (2006) Electrochem Commun 8:581

    Article  CAS  Google Scholar 

  32. Chikae M, Idegami K, Kerman K, Nagatani N, Ishikawa M, Takamura Y, Tamiya E (2006) Electrochem Commun 8:1375

    Article  CAS  Google Scholar 

  33. Li J, Lin XQ (2007) Anal Chim Acta 596:222

    Article  CAS  Google Scholar 

  34. Ren W, Luo HQ, Li NB (2006) Biosens Bioelectron 21:1086

    Article  CAS  Google Scholar 

  35. Sun YX, Wang SF, Zhang XH, Huang YF (2006) Sens Actuators B 113:156

    Article  CAS  Google Scholar 

  36. Gong J, Lin X (2004) Electrochim Acta 49:4351

    Article  CAS  Google Scholar 

  37. Yogeswaran U, Chen SM (2008) Sens Actuators B Chem 130:739

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This work was supported by National Science Council of Taiwan (ROC).

Author information

Authors and Affiliations

  1. Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No.1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, Republic of China

    Soundappan Thiagarajan & Shen-Ming Chen

Authors
  1. Soundappan Thiagarajan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shen-Ming Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shen-Ming Chen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thiagarajan, S., Chen, SM. Applications of nanostructured Pt-Au hybrid film for the simultaneous determination of catecholamines in the presence of ascorbic acid. J Solid State Electrochem 13, 445–453 (2009). https://doi.org/10.1007/s10008-008-0582-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10008-008-0582-7

Keywords

Search

Navigation