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Coagulase-negative staphylococci: update on the molecular epidemiology and clinical presentation, with a focus on Staphylococcus epidermidis and Staphylococcus saprophyticus

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Abstract

Coagulase-negative staphylococci (CoNS), originally described as ubiquitous commensals of the healthy human skin and mucosa, have emerged as important opportunistic pathogens primarily causing healthcare-associated infections in patients with indwelling medical devices. Recent studies, utilizing new molecular typing methods, particularly on Staphylococcus epidermidis, have increased our understanding of the mechanisms that contribute to the evolutionary success of these extremely versatile microorganisms. In the following mini-review, we summarize recent research in this area focusing on the molecular methods and epidemiology of S. epidermidis and S. saprophyticus.

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Authors and Affiliations

  1. Department of Infectious Diseases, Östersund Hospital, 831 83, Östersund, Sweden

    M. Widerström

  2. Department of Infectious Diseases, University Hospital of Umeå, 901 85, Umeå, Sweden

    J. Wiström

  3. Department of Clinical Bacteriology, University Hospital of Umeå, 901 85, Umeå, Sweden

    M. Widerström, A. Sjöstedt & T. Monsen

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  1. M. Widerström
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  4. T. Monsen
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Widerström, M., Wiström, J., Sjöstedt, A. et al. Coagulase-negative staphylococci: update on the molecular epidemiology and clinical presentation, with a focus on Staphylococcus epidermidis and Staphylococcus saprophyticus . Eur J Clin Microbiol Infect Dis 31, 7–20 (2012). https://doi.org/10.1007/s10096-011-1270-6

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