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Multiscale analysis of the coupled effects governing the movement of interstitial fluid in cortical bone

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Abstract

A multiscale approach (periodic homogenization) is carried out to model osteon’s behaviour, and especially the coupled phenomena that govern its interstitial fluid movement. Actions of electro-osmotic and osmotic motions in addition to the classical Poiseuille flow are studied at the mesoscale of the canaliculus and within the micropores of the collagen-apatite matrix. Use of this fully coupled modelling leads to a comparison of these different effects. Limitation of a classical Darcian description of the fluid flow at the two scales is so studied. For each of these studies a special attention is given to the pore’s geometry influence and to their electrical and hydraulic properties

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Authors and Affiliations

  1. Laboratoire de Mécanique Physique, CNRS UMR 7052 B2OA Faculté des Sciences et Technologie, Université Paris XII-Val de Marne, 61, Avenue du Général de Gaulle, 94010, Créteil Cédex, France

    Thibault Lemaire, Salah Naïli & Agnès Rémond

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  1. Thibault Lemaire
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  2. Salah Naïli
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  3. Agnès Rémond
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Correspondence to Salah Naïli.

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Lemaire, T., Naïli, S. & Rémond, A. Multiscale analysis of the coupled effects governing the movement of interstitial fluid in cortical bone. Biomech Model Mechanobiol 5, 39–52 (2006). https://doi.org/10.1007/s10237-005-0009-7

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  • DOI: https://doi.org/10.1007/s10237-005-0009-7

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