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Supply chain network operations management of a blood banking system with cost and risk minimization

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Abstract

Blood service operations are a key component of the healthcare system all over the world and yet the modeling and the analysis of such systems from a complete supply chain network optimization perspective have been lacking due to their associated unique challenges. In this paper, we develop a generalized network optimization model for the complex supply chain of human blood, which is a life-saving, perishable product. In particular, we consider a regionalized blood banking system consisting of collection sites, testing and processing facilities, storage facilities, distribution centers, as well as points of demand, which, typically, include hospitals. Our multicriteria system-optimization approach on generalized networks with arc multipliers captures many of the critical issues associated with blood supply chains such as the determination of the optimal allocations, and the induced supply-side risk, as well as the induced cost of discarding the waste, while satisfying the uncertain demands as closely as possible. The framework that we present is also applicable, with appropriate modifications, to the optimization of other supply chains of perishable products.

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References

  • Ahumada O, Villalobos JR (2009) Application of planning models in the agri-food supply chain: a review. Eur J Oper Res 195: 1–20

    Article  Google Scholar 

  • Boppana RV, Chalasani S (2007) Analytical models to determine desirable blood acquisition rates. In: IEEE international conference on system of systems engineering

  • Cetin E, Sarul LS (2009) blood bank location model: a multiobjective approach. Eur J Pure Appl Math 2(1): 112–124

    Google Scholar 

  • Cohen MA, Pierskalla WP (1979) Target inventory levels for a hospital blood bank or a decentralized regional blood banking system. Transfusion 19(4): 444–454

    Article  Google Scholar 

  • Dong J, Zhang D, Nagurney A (2004) A supply chain network equilibrium model with random demands. Eur J Oper Res 156: 194–212

    Article  Google Scholar 

  • Dupuis P, Nagurney A (1993) Dynamical systems and variational inequalities. Ann Oper Res 44: 9–42

    Article  Google Scholar 

  • Federgruen A, Prastacos G, Zipkin P (1986) allocation and distribution model for perishable products. Oper Res 34(1): 75–82

    Article  Google Scholar 

  • Georgiadis P, Vlachos D, Iakovou E (2005) A system dynamics modeling framework for the strategic supply chain management of food chains. J Food Eng 70: 351–364

    Article  Google Scholar 

  • Ghandforoush P, Sen TK (2010) DSS to manage platelet production supply chain for regional blood centers. Decis Support Syst 50(1): 32–42

    Article  Google Scholar 

  • Haijema R (2008) Solving large structured Markov decision problems for perishable—inventory management and traffic control. PhD thesis, Tinbergen Institute, The Netherlands

  • Haijema R, van der Wal J, Dijk NM (2007) Blood platelet production: optimization by dynamic programming and simulation. Comput Oper Res 34: 760–779

    Article  Google Scholar 

  • Hsu CI, Hung SF, Li HC (2007) Vehicle routing problem with time-windows for perishable food delivery. J Food Eng 80: 465–475

    Article  Google Scholar 

  • Hwang H, Hahn KH (2000) An optimal procurement policy for items with an inventory level-dependent demand rate and fixed lifetime. Eur J Oper Res 127(3): 537–545

    Article  Google Scholar 

  • Jacobs D, Silan M, Clemson B (1996) An analysis of alternative locations and service areas of American Red Cross blood facilities. Interfaces 26(3): 40–50

    Article  Google Scholar 

  • Karaesmen IZ, Scheller-Wolf A, Deniz B (2011) Managing perishable and aging inventories: review and future research directions. In: Kempf KG, Kskinocak P, Uzsoy P (eds) Planning production and inventories in the extended enterprise. Springer, Berlin, pp 393–436

    Chapter  Google Scholar 

  • Katsaliaki K, Brailsford SC (2007) Using simulation to improve the blood supply chain. J Oper Res Soc 58: 219–227

    Google Scholar 

  • Mustafee N, Katsaliaki K, Brailsford SC (2009) Facilitating the analysis of a UK national blood service supply chain using distributed simulation. Simulation 85(2): 113–128

    Article  Google Scholar 

  • Nagurney A (1999) Network economics: a variational inequality approach, second and revised edition. Kluwer, Dordrecht

    Google Scholar 

  • Nagurney A (2009) A system-optimization perspective for supply chain network integration: the horizontal merger case. Transp Res E 45: 1–15

    Article  Google Scholar 

  • Nagurney A (2010a) Supply chain network design under profit maximization and oligopolistic competition. Transp Res E 46: 281–294

    Article  Google Scholar 

  • Nagurney A (2010b) Optimal supply chain network design and redesign at minimal total cost and with demand satisfaction. Int J Prod Econ 128: 200–208

    Article  Google Scholar 

  • Nagurney A (2010c) Formulation and analysis of horizontal mergers among oligopolistic firms with insights into the merger paradox: a supply chain network perspective. Comput Manag Sci 7: 377–401

    Article  Google Scholar 

  • Nagurney A, Aronson J (1989) A general dynamic spatial price network equilibrium model with gains and losses. Networks 19(7): 751–769

    Article  Google Scholar 

  • Nagurney A, Nagurney LS (2010) Sustainable supply chain network design: a multicriteria perspective. Int J Sustain Eng 3: 189–197

    Article  Google Scholar 

  • Nagurney A, Qiang Q (2009) Fragile networks: identifying vulnerabilities and synergies in an uncertain world. Wiley, Hoboken

    Google Scholar 

  • Nagurney A, Woolley T (2010) Environmental and cost synergy in supply chain network integration in mergers and acquisitions. In: Ehrgott M, Naujoks B, Stewart T, Wallenius J (eds) Sustainable energy and transportation systems. Proceedings of the 19th international conference on multiple criteria decision making. Lecture notes in economics and mathematical systems. Springer, Berlin, pp 51–78

  • Nagurney A, Zhang D (1996) Projected dynamical systems and variational inequalities with applications. Kluwer, Boston

    Google Scholar 

  • Nagurney A, Cruz J, Dong J, Zhang D (2005) Supply chain networks, electronic commerce, and supply side and demand side risk. Eur J Oper Res 164: 120–142

    Article  Google Scholar 

  • Nagurney A, Yu M, Qiang Q (2011) Supply chain network design for critical needs with outsourcing. Papers Reg Sci 90(1): 123–143

    Article  Google Scholar 

  • Nahmias S (1982) Perishable inventory theory: a review. Oper Res 30(4): 680–708

    Article  Google Scholar 

  • Omosigho SE (2002) Determination of outdate and shortage quantities in the inventory problem with fixed lifetime. Int J Comput Math 79(11): 1169–1177

    Article  Google Scholar 

  • Osvald A, Stirn L (2008) A vehicle routing algorithm for the distribution of fresh vegetables and similar perishable food. J Food Eng 85: 285–295

    Article  Google Scholar 

  • Pierskalla WP (2004) Supply chain management of blood banks. In: Brandeau ML, Sanfort F, Pierskalla WP (eds) Operations research and health care: a handbook of methods and applications. Kluwer, Boston, pp 103–145

    Google Scholar 

  • Prastacos GP (1984) Blood inventory management: an overview of theory and practice. Manag Sci 30(7): 777–800

    Article  Google Scholar 

  • Redcrossblood.org. (2010) Donation FAQs. http://www.redcrossblood.org/donating-blood/donation-faqs

  • Rios J (2010) Interview with the Medical Director for the American Red Cross Northeast Division Blood Services. Dedham, Massachusetts on July 19, 2010

  • Rytila JS, Spens KM (2006) Using simulation to increase efficiency in blood supply chains. Manag Res News 29(12): 801–819

    Article  Google Scholar 

  • Sahin G, Sural H, Meral S (2007) Locational analysis for regionalization of Turkish Red Crescent blood services. Comput Oper Res 34: 692–704

    Article  Google Scholar 

  • Sivakumar P, Ganesh K, Parthiban P (2008) Multi-phase composite analytical model for integrated allocation-routing problem—application of blood bank logistics. Int J Logist Econ Global 1(3/4): 251–281

    Article  Google Scholar 

  • Sullivan M, Cotten R, Read E, Wallace E (2007) Blood collection and transfusion in the United States in 2001. Transfusion 47: 385–394

    Article  Google Scholar 

  • The New York Times (2010) In a world of throwaways, making a dent in medical waste. Chen, I., July 5. http://www.nytimes.com/2010/07/06/health/06waste.html

  • Walker L (2010) Phone interview with the Director of Business Development for the American Red Cross Blood Services in the Greater Boston Area on July 14

  • Whitaker BI, Green J, King MR, Leibeg LL, Mathew SM, Schlumpf KS, Schreiber GB (2007) The 2007 national blood collection and utilization survey report. The United States Department of Health and Human Services

  • Yang X (2006) Choosing transportation alternatives for highly perishable goods: a case study on nuclear medicine. Masters thesis, Massachusetts Institute of Technology, Cambridge

  • Yegul M (2007) Simulation analysis of the blood supply chain and a case study. Master’s thesis, Middle East Technical University, Turkey

  • Zanoni S, Zavanella L (2007) Single-vendor single-buyer with integrated transport-inventory system: Models and heuristics in the case of perishable goods. Comput Ind Eng 52: 107–123

    Article  Google Scholar 

  • Zhou YW, Yang SL (2003) An optimal replenishment policy for items with inventory-level-dependent demand and fixed lifetime under the LIFO policy. J Oper Res Soc 54(6): 585–593

    Article  Google Scholar 

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Correspondence to Anna Nagurney.

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Nagurney, A., Masoumi, A.H. & Yu, M. Supply chain network operations management of a blood banking system with cost and risk minimization. Comput Manag Sci 9, 205–231 (2012). https://doi.org/10.1007/s10287-011-0133-z

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