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Integrated wireless neural interface based on the Utah electrode array

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Abstract

This report presents results from research towards a fully integrated, wireless neural interface consisting of a 100-channel microelectrode array, a custom-designed signal processing and telemetry IC, an inductive power receiving coil, and SMD capacitors. An integration concept for such a device was developed, and the materials and methods used to implement this concept were investigated. We developed a multi-level hybrid assembly process that used the Utah Electrode Array (UEA) as a circuit board. The signal processing IC was flip-chip bonded to the UEA using Au/Sn reflow soldering, and included amplifiers for up to 100 channels, signal processing units, an RF transmitter, and a power receiving and clock recovery module. An under bump metallization (UBM) using potentially biocompatible materials was developed and optimized, which consisted of a sputter deposited Ti/Pt/Au thin film stack with layer thicknesses of 50/150/150 nm, respectively. After flip-chip bonding, an underfiller was applied between the IC and the UEA to improve mechanical stability and prevent fluid ingress in in vivo conditions. A planar power receiving coil fabricated by patterning electroplated gold films on polyimide substrates was connected to the IC by using a custom metallized ceramic spacer and SnCu reflow soldering. The SnCu soldering was also used to assemble SMD capacitors on the UEA. The mechanical properties and stability of the optimized interconnections between the UEA and the IC and SMD components were measured. Measurements included the tape tests to evaluate UBM adhesion, shear testing between the Au/Sn solder bumps and the substrate, and accelerated lifetime testing of the long-term stability for the underfiller material coated with a a-SiCx:H by PECVD, which was intended as a device encapsulation layer. The materials and processes used to generate the integrated neural interface device were found to yield a robust and reliable integrated package.

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Acknowledgment

This work was supported in part by NIH/NINDS Contract HHSN265200423621C and by DARPA under Contract N66001-06-C-8005. The authors gratefully acknowledge the colleagues at Fraunhofer IZM for their technical assistance in setup and conducting IC bumping, flip chip bonding and SMD reflow soldering.

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Authors and Affiliations

  1. Department of Electrical and Computer Engineering, University of Utah, 50 South Central Campus Drive, Salt Lake City, UT, 84112, USA

    S. Kim, R. Bhandari, S. Negi, L. Rieth, P. Tathireddy & F. Solzbacher

  2. Fraunhofer Institute for Reliability and Microintegration (IZM), Gustav-Meyer-Allee 25, 13355, Berlin, Germany

    M. Klein, M. Toepper & H. Oppermann

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  1. S. Kim
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  2. R. Bhandari
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  3. M. Klein
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  4. S. Negi
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  5. L. Rieth
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  7. M. Toepper
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  8. H. Oppermann
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  9. F. Solzbacher
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Correspondence to S. Kim.

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Kim, S., Bhandari, R., Klein, M. et al. Integrated wireless neural interface based on the Utah electrode array. Biomed Microdevices 11, 453–466 (2009). https://doi.org/10.1007/s10544-008-9251-y

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