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Erschienen in:

01.06.2012 | Original Paper

Synthesis and characterization of a novel polymeric hydrogel based on hydroxypropyl methyl cellulose grafted with polyacrylamide

verfasst von: R. Das, A. B. Panda, Sagar Pal

Erschienen in: Cellulose | Ausgabe 3/2012

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Abstract

A novel hydrogel has synthesized by grafting polyacrylamide chains onto hydroxypropyl methylcellulose in presence of potassium persulphate as initiator using solution polymerization technique. The reaction was carried out in homogeneous aqueous medium. The effect of reaction parameters on percentage of grafting (% G) and grafting efficiency (% GE) were discussed. The parameters were varied systematically to achieve the best hydrogel. Developed hydrogels were characterized by various materials characterization techniques. The dynamic and equilibrium swelling properties of hydrogels were investigated as a function of pH and time in various buffer solutions similar to that of gastric and intestinal fluid. Results showed that with increase in % G and % GE, the rate of swelling decreases, which can opens the door for further study of their utilization as matrices for controlled/sustained/targeted drug delivery.

Vorheriger Artikel Homogenous synthesis of 3-allyloxy-2-hydroxypropyl-cellulose in NaOH/urea aqueous system

Nächster Artikel Synthesis and characterization of antibacterial semi-interpenetrating carboxymethyl chitosan/poly (acrylonitrile) hydrogels

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Titel: Synthesis and characterization of a novel polymeric hydrogel based on hydroxypropyl methyl cellulose grafted with polyacrylamide
verfasst von: R. Das
A. B. Panda
Sagar Pal
Publikationsdatum: 01.06.2012
Verlag: Springer Netherlands
Erschienen in: Cellulose / Ausgabe 3/2012
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI: https://doi.org/10.1007/s10570-012-9692-6

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