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Hydrogels for medical applications fabricated by oxidative-hydrolytic modification of cellulose

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Fibre Chemistry Aims and scope

Abstract

Use of nitrate oxidants (HNO3 or N2O4), each of which causes both oxidation and hydrolysis of cellulose, is proposed for one-or two-stage transformation of native cellulose into microcrystalline cellulose topochemically modified with carboxyl groups. Conversion of the acid form of the preparations into the salt forms (sodium, lithium) makes it easy to obtain stable thixotropic hydrogels, revealed to be effective enterosorbents and drug vehicles in clinical trials.

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References

  1. O. A. Battista, Microcrystal Polymer Science, McGraw-Hill, New York (1975).

    Google Scholar 

  2. E. V. Gert, M. V. Shishonok, et al., Vysokomolek. Soedin., 37A, No. 7, 1130–1136 (1995).

    Google Scholar 

  3. O. V. Zubets, V. I. Torgashov, et al., in: Proceedings of the International Scientific Conference “New Drugs: Synthesis, Technology, Pharmacology, Clinical Aspects” [in Russian], Minsk (2001), pp. 53–54.

  4. V. I. Torgashov, O. V. Zubets, et al., Proceedings of the International Scientific Conference “New Drugs: Synthesis, Technology, Pharmacology, Clinical Aspects” [in Russian], Minsk (2001)Ibid., pp. 147–148.

  5. V. I. Torgashov, E. V. Gert, et al., Proceedings of the International Scientific Conference “New Drugs: Synthesis, Technology, Pharmacology, Clinical Aspects” [in Russian], Minsk (2001)Ibid., pp. 148–149.

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Authors and Affiliations

  1. Institute of Belorussian State University, Scientific-Research Institute of Physicochemical Problems, Minsk

    F. N. Kaputskii, E. V. Gert, V. I. Torgashov & O. V. Zubets

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  1. F. N. Kaputskii
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  2. E. V. Gert
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  3. V. I. Torgashov
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  4. O. V. Zubets
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Translated from Khimicheskie Volokna, No. 6, pp. 59–62, November–December, 2005.

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Kaputskii, F.N., Gert, E.V., Torgashov, V.I. et al. Hydrogels for medical applications fabricated by oxidative-hydrolytic modification of cellulose. Fibre Chem 37, 485–489 (2005). https://doi.org/10.1007/s10692-006-0026-z

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  • DOI: https://doi.org/10.1007/s10692-006-0026-z

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