Skip to main content

Advertisement

SpringerLink
Log in

Structural characterization of zinc-substituted hydroxyapatite prepared by hydrothermal method

  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

Zinc-substituted hydroxyapatite (Zn-HA) powders were prepared by hydrothermal method using Ca(NO3)2, (NH4)3PO4 and Zn(NO3)2 as reagents. X-ray fluorescence spectroscopy (XRF), X-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR) and transmission electron microscopy (TEM) were used to characterize the crystalline phase, microstructure, chemical composition, morphology and thermal stability of Zn-HA. The results show that the substitution content of zinc (Zn) in Zn-HA powders prepared in NaOH solution is higher than that prepared in NH3 solution, and is lower than that of the corresponding amount of starting materials. The substitution of the Zn ion for calcium ion causes a lower crystallinity of Zn-HA and changes the lattice parameters of Zn-HA, since the ionic radius is smaller in Zn2+ (0.074 nm) than in Ca2+ (0.099 nm). Furthermore, the substitution of the Zn ions restrains the growth of Zn-HA crystal and decreases the thermal stability of Zn-HA. Zn-HA powder prepared in NH3 solution starts to decompose at 800 °C when the Zn fraction increases to 15 mol%, while that prepared in NaOH solution start to decompose at 5 mol% Zn. The substitution content of Zn significantly influences the thermal stability, microstructure and morphology of Zn-HA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. I. MAYER and J. D. B. FEATHERSTONE, J. Cryst. Growth 219 (2000) 98

    Article  CAS  Google Scholar 

  2. S. BEN ABDELKADER, I. KHATTECH, C. REY and M. JEMAL, Thermochim. Acta. 376 (2001) 25

    Article  CAS  Google Scholar 

  3. G. DACULSI, R. Z. LEGEROS, M. HEUGHEBAERT and I. BARBIEUX, Calcif. Tissue Int. 46 (1990) 20

    Article  CAS  Google Scholar 

  4. I. R. GIBSON, K. A. HING, J. D. REVELL, J. D. SANTOS, S. M. BEST and W. BONFIELD, Key Eng. Mater. 203 (2002) 218

    Google Scholar 

  5. M. OKAZAKI, Biomaterials 16 (1995) 703

    Article  CAS  Google Scholar 

  6. I. R. GIBSON and W. Bonfield, J. Biomed. Mater. Res. 59 (2002) 697

    Article  CAS  Google Scholar 

  7. E. BERTONI, A. BIGI, G. COJAZZI, M. GANDOLFI, S. PANZAVOLTA and N. ROVER, J. Inorg. Biochem. 29 (1998) 72

    Google Scholar 

  8. R. Z. LEGEROS and J. P.LEGROS, in “Phosphate Minerals”, Edited by J. O. NRIAGU and P. B. MOORE (Springer-Verlag, New York, 1984) p. 351

  9. E. JALLOT, J. L. IRIGARAY, H. OUDADESSE, V. BRUN, G. WEBER and P. FRAYSSINET, Eur. Phys. J. App. phys. 6 (1999) 205

    Article  CAS  Google Scholar 

  10. J. H. BEATTIE and A. ALISON, Nutr. Res. Rev. 5 (1992) 1672

    Article  Google Scholar 

  11. E. J. UNDERWOOD, in “Trace Elements in Human and Animal Nutrition” (Academic Press, London, 1977) p. 196

  12. E. I. HAMILTON, M. J. MINSKI, J. J. CLEARY, Sci. Total Environ. 1 (1972/1973) 341

    Article  Google Scholar 

  13. WHO Expert Committee, WHO Tech. Rep. Ser. 532 (1973) 9

    Google Scholar 

  14. W. J. BETTGER and B. L. O’DELL, J. Nutr. Biochem. 4 (1993) 194

    Article  CAS  Google Scholar 

  15. M. YAMAGUCHI, K. INAMOTO and Y. E. SUKETA, Res. Exp. Med. 186 (1986) 337

    Article  CAS  Google Scholar 

  16. M. YAMAGUCHI, H. OISHI and Y. SUKETA, Biochem. Pharmacol. 36 (1987) 4007

    Article  CAS  Google Scholar 

  17. M. YAMAGUCHI, H. OISHI and Y. SUKETA, Biochem. Pharmacol. 37 (1988) 4075

    Article  CAS  Google Scholar 

  18. M. HASHIZUME and M. YAMAGUCHI, Mol. Cell. Biochem. 122 (1993) 59

    Article  CAS  Google Scholar 

  19. S. KISI, M. YAMAGUCHI, Biochem. Pharmacol. 48 (1994) 1225

    Article  Google Scholar 

  20. B. BAO, A. S. PRASAD, F. W. BECK and M. GODMERE, Am. J. Physiol. Endocrinol. Metab. 285 (2003) E1095–102

    CAS  Google Scholar 

  21. A. GRANDJEAN-LAQUERRIERE, P. LAQUERRIERE, E. JALLOT, J. M. NEDELEC, M. GUENOUNOU and D. LAURENT-MAQUIN, Biomaterials 27 (2006) 3195

    Article  CAS  Google Scholar 

  22. E. JALLOT, J. M. NEDELEC, A. S. GRIMAULT, E. CHASSOT, A. GRANDJEAN-LAQUERRIERE, P. LAQUERRIERE and D. LAURENT-MAQUIN, Colloids Surf. B Biointerfaces 42 (2005) 205

    Article  CAS  Google Scholar 

  23. E. FUJII, M. OHKUBO, K. TSURU, S. HAYAKAWA, A. OSAKA, K. KAWABATA, C. BONHOMME and F. BABONNEAU, Acta Biomaterialia. 2 (2006) 69

    Article  Google Scholar 

  24. S. D. MIAO, W. J. WENG, K. CHENG, P. Y. DU, G. SHEN, G. R. HAN and S. ZHANG, Surf. Coat. Technol. 198 (2005) 223

    Article  CAS  Google Scholar 

  25. F. MIYAJI, Y. KONO and Y. SUYAMA, Mater. Res. Bull. 40 (2005) 209

    Article  CAS  Google Scholar 

  26. R. Z. LEGEROS, C. B. BLEIWAS, M. RETINO, R. ROHANIZADEH and J. P. LEGEROS, Am. J. Dent. 12 (1999) 65

    CAS  Google Scholar 

  27. W. L. JOLLY, in “The Synthesis and Characterization of Inorganic Compounds” (Prentice Hall, Englewood Cliffs, NJ, 1970) p. 231

  28. A. ITO, K. OJIMA, H. NAITO, N. ICHINOSE and T. TATEISHI, J. Biomed. Mater. Res. 50 (2000) 178

    Article  CAS  Google Scholar 

  29. C. B. BADDIELANG and E. E. Berry, J. Spectro. Chim. Acta. 22 (1996) 1407

    Article  Google Scholar 

  30. P. F. GONZALEZ-DIAZ and M. SANDTOS, J. Solid State Chem. 22 (1997) 193

    Article  Google Scholar 

  31. E. BOUYER, F. GITZHOFER, I. BOULOS, J. Mater. Sci., Mater. Med. 11 (2000) 523

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors would like to thank National Nature Science Foundation of China (30600149), the science research foundation of ministry of Health & United Fujian Provincial Health and Education Project for Tackling the Key Research, P.R. China (WKJ 2005-2-008), Fujian Development and Reform Commission of China (No. 2004[477]) and Undergraduate extracurricular project of Fujian Normal University (BKL2006-021).

Author information

Authors and Affiliations

  1. College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, 350007, China

    Ming’Ou Li, Xiufeng Xiao, Rongfang Liu, Cuiyu Chen & Lizhong Huang

Authors
  1. Ming’Ou Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xiufeng Xiao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rongfang Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Cuiyu Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Lizhong Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rongfang Liu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, M., Xiao, X., Liu, R. et al. Structural characterization of zinc-substituted hydroxyapatite prepared by hydrothermal method. J Mater Sci: Mater Med 19, 797–803 (2008). https://doi.org/10.1007/s10856-007-3213-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10856-007-3213-4

Keywords

Search

Navigation