Skip to main content
SpringerLink
Log in

Single walled carbon nanotubes (SWCNT) affect cell physiology and cell architecture

  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

Single walled carbon nanotubes (SWCNT) find their way in various industrial applications. Due to the expected increased production of various carbon nanotubes and nanoparticle containing products, exposure to engineered nanoparticles will also increase dramatically in parallel. In this study the effects of SWCNT raw material and purified SWCNT (SWCNT bundles) on cell behaviour of mesothelioma cells (MSTO-211H) and on epithelial cells (A549) had been investigated. The effect on cell behaviour (cell proliferation, cell activity, cytoskeleton organization, apoptosis and cell adhesion) were dependent on cell type, SWCNT quality (purified or not) and SWCNT concentration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

Abbreviations

SWCNT:

Single walled carbon nanotubes

MWCNT:

Multi walled carbon nanotubes

CNT:

Carbon nanotubes

References

  1. S. IIJIMA, Nature 354 (1991) 56

    Article  CAS  Google Scholar 

  2. T. GUO, P. NIKOLAEV, A. THESS, D. T. COLBERT and R. E. Smalley, Chem. Phys. Lett. 243 (1995) 49

    Article  CAS  Google Scholar 

  3. A. M. CASSELL, J. A. RAYMAKERS, J. KONG and H. DAI, J. Phys. Chem. B 103 (1999) 6484

    Article  CAS  Google Scholar 

  4. A. G. RINZLER, J. LIU, H. DAI, P. NIKOLAEV, C. B. HUFFMAN, F. J. RODRIGUEZ-MACIAS, P. J. BOUL, A. H. LU, D. HEYMANN, D. T. COLBERT, J. E. LEE, A. M. RAO, P. C. EKLUND and R. E. SMALLEY, Appl. Phys. A 67 (1998) 29

    Article  CAS  Google Scholar 

  5. H. MIYAGAWA, M. MISRA and A. K. MOHANTY, J. Nanosci. Nanotechnol. 5 (2005) 1593

    Article  CAS  Google Scholar 

  6. N. DE JONGE and J. M. BONARD, Philos. Transact. Ser. A. Math. Phys. Eng. Sci. 362 (2004) 2239

    Article  Google Scholar 

  7. A. BIANCO, K. KOSTARELOS and M. PRATO, Curr. Opin. Chem. Biol. 9 (2005) 674

    Article  CAS  Google Scholar 

  8. G. JIA, H. WANG, L. YAN, X. WANG, R. PEI, T. YAN, et al., Environ. Sci. Technol. 39 (2005) 1378

    Article  CAS  Google Scholar 

  9. J. MULLER, F. HUAUX, N. MOREAU, P. MISSON, J.-F. HEILIER, M. DELOS, et al., Toxicol. Appl. Pharmaco. 207 (2005) 221

    CAS  Google Scholar 

  10. C. M. SAYES, F. LIANG, J. L. HUDSON, J. MENDEZ, W. GUO, J.M. BEACH, et al, Toxicol. Lett. 161 (2006) 135

    Article  CAS  Google Scholar 

  11. A. HELLAND, P. WICK, A. KOEHLER, K. SCHMID, C. SOM, Environ. Health Persp. (2007) doi:10.1289/ehp.9652

  12. C. W. LAM, J. T. JAMES, R. MCCLUSKEY, S. AREPALLI and R. L. HUNTER, Crit. Rev. Toxicol. 36 (2006) 189

    Article  CAS  Google Scholar 

  13. J. M. WORLE-KNIRSCH, K. PULSKAMP and H. F. KRUG, Nano Lett. 6 (2006) 1261

    Article  CAS  Google Scholar 

  14. F. TIAN, D. CUI, H. SCHWARZ, G. G. ESTRADA and H. KOBAYASHI, Toxicol. in Vitro 20 (2006) 1202

    Article  CAS  Google Scholar 

  15. A. HUCZKO and A. LANGE, Fullerene Sci. Tech. 9 (2001) 247

    CAS  Google Scholar 

  16. C. W. LAM, J. T. JAMES, R. MCCLUSKEY and R. L. HUNTER, Toxicol. Sci. 77 (2004) 126

    Article  CAS  Google Scholar 

  17. J. MULLER, F. HUAUX, N. MOREAU, P. MISSON, J. F. HEILIER and M. DELOS, Toxicol. Appl. Pharm. 207 (2005) 221

    CAS  Google Scholar 

  18. D. CUI, F. TIAN, C. S. OZKAN, M. WANG, H. GAO, Toxicol. Lett. 155 (2005) 73

    Article  CAS  Google Scholar 

  19. P. WICK, P. MANSER, L. K. LIMBACH, U. DETTLAFF-WEGLIKOWSKA, F. KRUMREICH, S. ROTH, W. J. STARK and A. BRUININK, Toxicol. Lett. 168, 121 (2007)

    Article  CAS  Google Scholar 

  20. P. WICK, P. MANSER, P. SPOHN and A. BRUININK, Physica. Status. Solidi. 243 (2006) 3556

    Article  CAS  Google Scholar 

  21. C. D. NOBES and A. J. HALL, J. Cell. Biol. 144 (1999) 1235

    Article  CAS  Google Scholar 

  22. M. E. ITKIS, D. E. PEREA, S. NIYOGI, S. M. RICKARD, M. A. HAMON, H. HU, B. ZHAO and R. C. HADDON, Nano Lett. 3 (2003) 309

    Article  CAS  Google Scholar 

  23. A. BRUININK, E. WINTERMANTEL, Biomat. 22 (2001) 2465

    Article  CAS  Google Scholar 

  24. T. TAKEUCHI, M. NAKAJIMA and K. MORIMOTO, Mutat. Res. 438 (1999) 63

    CAS  Google Scholar 

  25. C. S. CHEN, M. MRKSICH, S. HUANG, G. M. WHITESSIDES and D. E. INGBER, Science 276 (1997) 1425

    Article  CAS  Google Scholar 

  26. A. BERSHADSKY, A. CHAUSOVSKY, E. BECKER, A. LYUBIMOVA and B. GEIGER, Curr. Biol. 6 (1996) 1279

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work has been supported by the European Commission through the integrated project CANAPE (Contract No. NMP4-CT-2004-500096), the Federal Office for Professional Education and Technology-Innovation Promotion Agency (OPET-CTI), the Swiss Agency for the Environment (BAFU) and the Swiss Federal Office of Public Health (BAG).

Author information

Authors and Affiliations

  1. Materials – Biology Interactions Laboratory, Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, CH-9014, Switzerland

    Jean-Pierre Kaiser, Peter Wick, Pius Manser, Philipp Spohn & Arie Bruinink

Authors
  1. Jean-Pierre Kaiser
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter Wick
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Pius Manser
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Philipp Spohn
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Arie Bruinink
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jean-Pierre Kaiser.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kaiser, JP., Wick, P., Manser, P. et al. Single walled carbon nanotubes (SWCNT) affect cell physiology and cell architecture. J Mater Sci: Mater Med 19, 1523–1527 (2008). https://doi.org/10.1007/s10856-007-3296-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10856-007-3296-y

Keywords

Search

Navigation