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Segmented biopolyurethanes for medical applications

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Abstract

Polyurethanes are one of the most popular groups of biomaterials applied for medical devices. Their segmented block copolymeric character endows them a wide range of versatility in terms of tailoring their physical properties, blood and tissue compatibility. Polyester- and polyether-urethanes have been modified with hydroxypropyl cellulose aiming the change of their surface and bulk characteristics to confer them biomaterial qualities. In this respect, dynamic contact angle measurements, dynamic mechanical analyses accompanied by mechanical testing have been done. Platelet adhesion test has been carried out in vitro and the use of hydroxypropyl cellulose in the polyurethane matrix reduces the platelet adhesion and therefore recommends them as candidates for biocompatible materials.

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Acknowledgements

The authors are grateful for the financial support, to Ministry of Education and Research—Exploratory Research Projects, Code: PN-II-ID-PCE-988/2008.

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Authors and Affiliations

  1. “Petru Poni” Institute of Macromolecular Chemistry, Iasi, 700487, Romania

    Doina Macocinschi, Daniela Filip, Stelian Vlad & Mariana Cristea

  2. Faculty of Medical Bioengineering, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, 700115, Romania

    Maria Butnaru

Authors
  1. Doina Macocinschi
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  2. Daniela Filip
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  3. Stelian Vlad
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  4. Mariana Cristea
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  5. Maria Butnaru
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Correspondence to Doina Macocinschi.

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Macocinschi, D., Filip, D., Vlad, S. et al. Segmented biopolyurethanes for medical applications. J Mater Sci: Mater Med 20, 1659–1668 (2009). https://doi.org/10.1007/s10856-009-3731-3

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  • DOI: https://doi.org/10.1007/s10856-009-3731-3

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