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Gallium containing glass polyalkenoate anti-cancerous bone cements: glass characterization and physical properties

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Abstract

A gallium (Ga) glass series (0.48SiO2–0.40ZnO–0.12CaO, with 0.08 mol% substitution for ZnO) was developed to formulate a Ga-containing Glass Polyalkenoate Cement (GPC) series. Network connectivity (NC) and X-ray Photoelectron Spectroscopy (XPS) was employed to investigate the role of Ga3+ in the glass, where it is assumed to act as a network modifier. Ga-GPC series was formulated with E9 and E11 polyacrylic acid (PAA) at 50, 55 and 60 wt% additions. E11 working times (T w ) ranged from 68 to 96 s (Lcon.) and 106 s for the Ga-GPCs (LGa-1 and LGa-2). Setting times (T s ) ranged from 104 to 226 s (Lcon.) and 211 s for LGa-1 and LGa-2. Compression (σc) and biaxial flexural (σf) testing were conducted where Lcon. increased from 62 to 68 MPa, LGa-1 from 14 to 42 MPa and LGa-2 from 20 to 47 MPa in σc over 1–30 days. σf testing revealed that Lcon. increased from 29 to 42 MPa, LGa-1 from 7 to 32 MPa and LGa-2 from 12 to 36 MPa over 1–30 days.

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Authors and Affiliations

  1. Inamori School of Engineering, Alfred University, Alfred, NY, 14802, USA

    A. W. Wren, A. Coughlan, L. Placek & M. R. Towler

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  1. A. W. Wren
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  2. A. Coughlan
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  4. M. R. Towler
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Correspondence to A. W. Wren.

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Wren, A.W., Coughlan, A., Placek, L. et al. Gallium containing glass polyalkenoate anti-cancerous bone cements: glass characterization and physical properties. J Mater Sci: Mater Med 23, 1823–1833 (2012). https://doi.org/10.1007/s10856-012-4624-4

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  • DOI: https://doi.org/10.1007/s10856-012-4624-4

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