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Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria

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Abstract

In this investigation, silver nanocomposite hydrogels were developed by using acrylamide and biodegradable gelatin. Silver nanoparticles were generated throughout the hydrogel networks using in situ method by incorporating Ag+ ions and the subsequent treatment with sodium borohydride. The effect of gelatin on the swelling studies was investigated. The hydrogel synthesized silver nanocomposites were characterized by using Fourier transform infrared, UV–Visible spectroscopy, X-ray diffraction, thermogravimetric analysis, scanning electron and transmission electron microscopy techniques. The biodegradable gelatin-based silver nanocomposite hydrogels were tested for antibacterial properties. The results indicate that these biodegradable silver nanocomposite hydrogels can be useful in medical applications, as antibacterial agents.

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References

  1. K. Varaprasad, K. Vimala, S. Ravindra, N. Narayana Reddy, G. Venkata Subba Reddy, K. Mohana Raju, J Mater Sci 22, 1863 (2011)

    CAS  Google Scholar 

  2. E.F. Dominic, G.R. José, G. Yong-kuan, K.H. Aaron Lau, H. Lihong, V. Rahul, P.B. Messersmith, Biomaterials 33, 3783 (2012)

    Article  Google Scholar 

  3. V. Ramesh Babu, C. Kim, S. Kim, C. Ahn, Y. Lee, Carbohydr Polym 81, 196 (2010)

    Article  Google Scholar 

  4. H. El-Sherif, M. El-Masry, A. Kansoh, Macromol Res 19, 1157 (2011)

    Article  CAS  Google Scholar 

  5. P.H. Corkhill, C.J. Hamilton, B.J. Tighe, Biomaterials 10, 3 (1989)

    Article  CAS  Google Scholar 

  6. K. Kabiri, H. Mirzadeh, M.J. Zohuriaan-Mehr, J Appl Polym Sci 116, 2548 (2010)

    CAS  Google Scholar 

  7. E.A. Appel, J. Barrio, X.J. Loh, O.A. Scherman, Chem Soc Rev 41, 6195 (2012)

    Article  CAS  Google Scholar 

  8. J.A. Cadée, M.J.A. Van Luyn, L.A. Brouwer, J.A. Plantinga, P.B. Van Wachem, C.J. Groot, W.D. Otter, W.E. Hennink, J Biomed Mater Res 50, 397 (2000)

    Article  Google Scholar 

  9. K. Varaprasad, Y. Murali Mohan, K. Vimala, K. Mohana Raju, J Appl Polym Sci 121, 784 (2011)

    Article  CAS  Google Scholar 

  10. S. Ravindra, A.F. Mulaba-Bafubiandi, V. Rajinikanth, K. Varaprasad, N. Narayana Reddy, K. Mohana Raju, J Inorg Organomet Polym 22, 1254 (2012)

    Article  CAS  Google Scholar 

  11. K. Varaprasad, Y. Murali Mohan, S. Ravindra, N. Narayana Reddy, K. Vimala, K. Monika, B. Sreedhar, K. Mohana Raju, J Appl Polym Sci 115, 1199 (2010)

    Article  CAS  Google Scholar 

  12. K. Varaprasad, Y. Murali Mohan, K. Vimala, K. Mohana Raju, J Appl Polym Sci 121, 784 (2011)

    Article  CAS  Google Scholar 

  13. P.S.K. Murthy, Y. Murali Mohan, K. Varaprasad, B. Sreedhar, K. Mohana Raju, J Colloids & Interface Sci 318, 217 (2008)

    Article  CAS  Google Scholar 

  14. Y. Murali Mohan, K. Vimala, T. Varsha, K. Varaprasad, B. Sreedhar, S.K. Bajpai, K. Mohana Raju, J Colloids & Interface Sci 342, 73 (2010)

    Article  CAS  Google Scholar 

  15. A. Hebeish, M. Hashem, M.M. Abd El-Hady, S. Sharaf, Carbohydr Polym 92, 407 (2013)

    Article  CAS  Google Scholar 

  16. X. Zhang, Y. Gozukara, P. Sangwan, D. Gao, S. Bateman, Poly Degr & Stab 95, 2309 (2010)

    Article  CAS  Google Scholar 

  17. E. Guibal, Sep Purif Technol 38, 43 (2004)

    Article  CAS  Google Scholar 

  18. A. Shimoda, Y. Yamamoto, S. Sawada, K. Akiyoshi, Macromol Res 20, 266 (2012)

    Article  CAS  Google Scholar 

  19. D.P. Huynh, C.T. Huynh, D. Sung Lee, Macromol Res 18, 589 (2010)

    Article  CAS  Google Scholar 

  20. K.A. Juby, C. Dwivedi, M. Kumar, K. Swathi, H.S. Misra, P.N. Bajaj, Carbohydr Poly 89, 906 (2012)

    Article  CAS  Google Scholar 

  21. H. Hezaveh, I.I. Muhamad, Carbohydr Polym 89, 138 (2012)

    Article  CAS  Google Scholar 

  22. Y. Zhou, Y. Zhao, W. Lu, L. Xu, M. Zhai, S. Wei, Radiat Phys & Chem 81, 553 (2012)

    Article  CAS  Google Scholar 

  23. J.Y. Lai, Y.T. Li, Biomacromole 11, 1387 (2010)

    Article  CAS  Google Scholar 

  24. G.V.N. Rathna, J Mater Sci 19, 2351 (2008)

    CAS  Google Scholar 

  25. D. Pasqui, M.D. Cagna, R. Barbucci, Polymers 4, 1517 (2012)

    Article  CAS  Google Scholar 

  26. T. Jayaramudu, G.M. Raghavendra, K. Varaprasad, R. Sadiku, K. Ramam, K. Mohana Raju, Carbohydr Polym 95, 188 (2013)

    Article  CAS  Google Scholar 

  27. N. Mithil Kumar, K. Varaprasad, G. Ramachandra Reddy, G. Siva Mohan Reddy, Y. Sivabharathi, G. Venkata Subba Reddy, S. Venkata Naidu, J Polym & Environ 19,, 225 (2011)

    Article  Google Scholar 

  28. P. Ranga Reddy, K. Varaprasad, N. Narayana Reddy, K. Mohana Raju, N. Subbarami Reddy, J Appl Polym Sci 125, 1357 (2012)

    Article  CAS  Google Scholar 

  29. T. Jayaramudu, G.M. Raghavendra, K. Varaprasad, K. Rotimi Sadiku, K. Mohana Raju, Carbohydr Polym 92, 2193–2200 (2013)

    Article  CAS  Google Scholar 

  30. S. Mohammad, H. Behrouz, Materials 4, 543 (2011)

    Article  Google Scholar 

  31. P. Rujitanaroj, N. Pimpha, P. Supaphol, Polymer 49, 4723 (2008)

    Article  CAS  Google Scholar 

  32. S. Galdiero, A. Falanga, M. Vitiello, M. Cantisani, V. Marra, M. Galdiero, Molecules 16, 8894 (2011)

    Article  CAS  Google Scholar 

  33. G.M. Raghavendra, T. Jayaramudu, K. Varaprasad, R. Sadiku, S.S. Ray, K.M. Raju, Carbohydr Polym 93, 553 (2013)

    Article  CAS  Google Scholar 

  34. K. Vimala, Y. Murali Mohan, K. Samba Sivudu, K. Varaprasad, S. Ravindra, N. Narayana Reddy, Y. Padma, B. Sreedhar, K. Mohana Raju, Colloids Surf B 76, 248 (2010)

    Article  CAS  Google Scholar 

  35. K. Vimala, Y.M. Mohan, K. Varaprasad, N.N. Reddy, S. Ravindra, N. Sudhakar Naidu, K. Mohana Raju, J Biomater Nanobiotechnol 2, 55 (2011)

    Article  CAS  Google Scholar 

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Acknowledgments

Two of the authors (KVP & KRM) thank the Fondecyt Proyecto No: 3130748 & 1110583 Chile (South America). The Authors (PRR & NSR) are grateful to the University Grants Commission, New Delhi, India for the financial support in the form of a Major Research Project.

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Authors and Affiliations

  1. Synthetic Polymer Laboratory, Department of Polymer Science & Technology, Sri Krishnadevaraya University, Anantapur, 515003, Andhra Pradesh, India

    P. Ranga Reddy, K. Mohana Raju & N. Subbarami Reddy

  2. Department of Polymer Technology, Tshwane University of Technology, CSIR Campus, Building 14D, Private Bag X025, Lynwood Ridge, Pretoria, 0040, South Africa

    K. Varaprasad & Rotimi Sadiku

  3. Departamento de Ingeniería de Materiales (DIMAT), Facultad de Ingeniería, Universidad de Concepción, Concepción, Chile

    K. Varaprasad & Koduri Ramam

  4. Department of Microbiology, Sri Krishnadevaraya University, Anantapur, 515003, Andhra Pradesh, India

    G. Venkata Subba Reddy

Authors
  1. P. Ranga Reddy
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  2. K. Varaprasad
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  3. Rotimi Sadiku
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  4. Koduri Ramam
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  5. G. Venkata Subba Reddy
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  6. K. Mohana Raju
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  7. N. Subbarami Reddy
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Correspondence to K. Varaprasad.

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Reddy, P.R., Varaprasad, K., Sadiku, R. et al. Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria. J Inorg Organomet Polym 23, 1054–1060 (2013). https://doi.org/10.1007/s10904-013-9886-x

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  • DOI: https://doi.org/10.1007/s10904-013-9886-x

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