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Journal of Nanoparticle Research
Erschienen in: Journal of Nanoparticle Research 5/2013

01.05.2013 | Research Paper

Cobalt-doped nanohydroxyapatite: synthesis, characterization, antimicrobial and hemolytic studies

verfasst von: Kashmira P. Tank, Kiran S. Chudasama, Vrinda S. Thaker, Mihir J. Joshi

Erschienen in: Journal of Nanoparticle Research | Ausgabe 5/2013

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Abstract

Hydroxyapatite (Ca10(PO4)6(OH)2; HAP) is a major mineral component of the calcified tissues, and it has various applications in medicine and dentistry. In the present investigation, cobalt-doped hydroxyapatite (Co-HAP) nanoparticles were synthesized by surfactant-mediated approach and characterized by different techniques. The EDAX was carried out to estimate the amount of doping in Co-HAP. The transmission electron microscopy result suggested the transformation of morphology from needle shaped to spherical type on increasing the doping concentration. The powder XRD study indicated the formation of a new phase of brushite for higher concentration of cobalt. The average particle size and strain were calculated using Williamson–Hall analysis. The average particle size was found to be 30–60 nm. The FTIR study confirmed the presence of various functional groups in the samples. The antimicrobial activity was evaluated against four organisms Pseudomonas aeruginosa and Shigella flexneri as Gram negative as well as Micrococcus luteus and Staphylococcus aureus as Gram positive. The hemolytic test result suggested that all samples were non-hemolytic. The photoluminescence study was carried out to identify its possible applicability as a fluorescent probe.
Vorheriger Artikel Facile synthesis of PANI-modified CoFe2O4–TiO2 hierarchical flower-like nanoarchitectures with high photocatalytic activity
Nächster Artikel Direct evidence of advantage of using nanosized zeolite Beta for ISFET-based biosensor construction

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Metadaten
Titel
Cobalt-doped nanohydroxyapatite: synthesis, characterization, antimicrobial and hemolytic studies
verfasst von
Kashmira P. Tank
Kiran S. Chudasama
Vrinda S. Thaker
Mihir J. Joshi
Publikationsdatum
01.05.2013
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 5/2013
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-013-1644-z

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