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Journal of Nanoparticle Research

Erschienen in:

01.09.2014 | Research Paper

In vitro comparative study of pure hydroxyapatite nanorods and novel polyethylene glycol/graphene oxide/hydroxyapatite nanocomposite

verfasst von: Fatemeh Mohandes, Masoud Salavati-Niasari

Erschienen in: Journal of Nanoparticle Research | Ausgabe 9/2014

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Abstract

In this work, crystalline hydroxyapatite (HAP) nanorods were first prepared by a simple precipitation method in the presence of a new capping agent based on Schiff base compounds, and then composite of polyethylene glycol (PEG), graphene oxide (GO), and the HAP nanorods was synthesized by freeze-drying method. X-ray diffraction patterns indicated that poor crystalline HAP powders produced in the absence of Schiff base were highly agglomerated. In addition, in vitro bioactivity of the produced HAP nanorods and PEG/GO/HAP nanocomposite was evaluated by soaking the products in simulated body fluid (SBF). The chemical composition of the SBF solutions was analyzed by inductively coupled plasma-optical emission spectrometry, and it was found that more Ca and P were released from the nanocomposite compared to the pure HAP nanorods, indicating high bioactivity of the nanocomposite. In addition, it was observed that the growth of new apatite on the surface of the nano-sized materials increased after immersion for 14 days in the SBF solution.

Vorheriger Artikel Synthesis of pure iron nanoparticles at liquid–liquid interface using pulsed plasma

Nächster Artikel An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles

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Babaei Z, Jahanshahi M, Rabiee SM (2013) The fabrication of nanocomposites via calcium phosphate formation on gelatin-chitosan network and the gelatin influence on the properties of biphasic composites. Mater Sci Eng C 33:370–375CrossRef

Das TK, Prusty S (2012) Graphene: a revolution in nanobiotechnology. J Res Nanobiotechnol 1:019–030

Deen I, Pang X, Zhitomirsky I (2012) Electrophoretic deposition of composite chitosan-halloysite nanotube-hydroxyapatite films. Colloids Surf A Physicochem Eng Asp 410:38–44CrossRef

Dhanalakshmi CP, Vijayalakshmi L, Narayanan V (2012) Synthesis and preliminary characterization of polyethylene glycol (PEG)/hydroxyapatite (HAp) nanocomposite for biomedical applications. Int J Phys Sci 7:2093–2101CrossRef

Hench LL (1991) Bioceramics: from concept to clinic. J Am Ceram Soc 74:1487–1510CrossRef

Hummers WS, Offeman RE (1958) Preparation of graphitic oxide. J Am Chem Soc 80:1339CrossRef

Itokawa H, Hiraide T, Moriya M, Fujimoto M, Nagashima G, Suzuki R, Fujimoto T (2007) A 12 month in vivo study on the response of bone to a hydroxyapatite-polymethylmethacrylate cranioplasty composite. Biomaterials 28:4922–4927CrossRef

Jarcho M (1981) Calcium phosphate ceramics as hard tissue prosthetics. Clin Orthop Relat Res 157:259–278

Jiao TF, Zhou J, Zhou JX, Gao LH, Xing YY, Li XH (2011) Synthesis and characterization of chitosan-based Schiff base compounds with aromatic substituent groups. Iran Poly J 20:123–126

Joshi SV, Srivastava MP, Pal A, Pal S (1993) Plasma spraying of biologically derived hydroxyapatite on implantable materials. J Mater Sci Mater Med 4:251–255CrossRef

Kaflak A, Slósarczyk A, Kolodziejski W (2011) A comparative study of carbonate bands from nanocrystalline carbonated hydroxyapatites using FT-IR spectroscopy in the transmission and photoacoustic modes. J Mol Struct 997:7–17CrossRef

Kasuga T, Ota Y, Nogami M, Abe Y (2000) Preparation and mechanical properties of polylactic acid composites containing hydroxyapatite fibers. Biomaterials 22:19–23CrossRef

Kheradmandfar M, Fathi MH, Ahangarian M, Zahrani EM (2012) In vitro bioactivity evaluation of magnesium-substituted fluorapatite nanopowders. Ceram Int 38:169–175CrossRef

Kim H, Namgung R, Singha K, Oh IK, Kim WJ (2011) Graphene oxide-polyethylenimine nanoconstruct as a gene delivery vector and bioimaging tool. Bioconjugate Chem 22:2558–2567CrossRef

Kokubo T, Takadama H (2006) How useful is SBF in predicting in vivo bone bioactivity. Biomaterials 27:2907–2915CrossRef

Li P, Ohtsuki C, Kokubo T (1994) The role of hydrated silica, Titania, and alumina in inducing apatite on implants. J Biomed Mater Res 28:7–15CrossRef

Li D, Muller MB, Gilje S, Kaner RB, Wallace GG (2008) Processable aqueous dispersions of graphene nanosheets. Nat Nanotechnol 3:101–105CrossRef

Li M, Wang Y, Liu Q, Li Q, Cheng Y, Zheng Y, Xi T, Wei S (2013) In situ synthesis and biocompatibility of nano hydroxyapatite on pristine and chitosan functionalized graphene oxide. J Mater Chem B 1:475–484CrossRef

Liu H, Xi P, Xie G, Shi Y, Hou F, Huang L, Chen F, Zeng Z, Shao C, Wang J (2012) Simultaneous reduction and surface functionalization of graphene oxide for hydroxyapatite mineralization. J Phys Chem C 116:3334–3341CrossRef

Marcano DC, Kosynkin DV, Berlin JM, Sinitskii A, Sun Z, Slesarev A, Alemany LB, Lu W, Tour JM (2010) Improved synthesis of graphene oxide. ACS Nano 4:4806–4814CrossRef

Marques P, Gonçalves G, Singh MK, Grácio J (2012) Graphene oxide and hydroxyapatite as fillers of polylactic acid nanocomposites: preparation and characterization. J Nanosci Nanotechnol 12:6686–6692CrossRef

Murugan R, Ramakrishna S (2004) Bioresorbable composite bone paste using polysaccharide based nano hydroxyapatite. Biomaterials 25:3829–3835CrossRef

Ni JH, Shi YL, Yan FY, Chen JZ, Wang L (2008) Preparation of hydroxyapatite-containing titania coating on titanium substrate by micro-arc oxidation. Mater Res Bull 43:45–53CrossRef

Novoselov KS, Geim AK, Morozov SV, Jiang D, Zhang Y, Dubonos SV, Grigorieva IV, Firsov AA (2004) Electric field effect in atomically thin carbon films. Science 306:666–669CrossRef

Polu AR, Kumar R, Causin V, Neppalli R (2011) Conductivity, XRD, and FTIR studies of new Mg2+ -ion-conducting solid polymer electrolytes: [PEG: Mg(CH3COO)2]. J Korean Phys Soc 59:114–118CrossRef

Rodriguez K, Renneckar S, Gatenholm P (2011) Biomimetic calcium phosphate crystal mineralization on electrospun cellulose based scaffolds. ACS Appl Mater Interface 3:681–689CrossRef

Sadat-Shojai M, Khorasani MT, Jamshidi A (2012) Hydrothermal processing of hydroxyapatite nanoparticles-A Taguchi experimental design approach. J Cryst Growth 361:73–84CrossRef

Spanos N, Misirlis DY, Kanellopoulou DG, Koutsoukos PG (2006) Seeded growth of hydroxyapatite in simulated body fluid. J Mater Sci 41:1805–1812CrossRef

Tavakoli F, Salavati-Niasari M (2014) A facile synthesis of CuI-graphene nanocomposite by glucose as a green capping agent and reductant. J Ind Eng Chem. doi:10.1016/j.jiec.2013.11.061

Venkatesan J, Qian ZJ, Ryu B, Kumar NA, Kim SK (2011) Preparation and characterization of carbon nanotube-grafted-chitosan-natural hydroxyapatite composite for bone tissue engineering. Carbohydr Poly 83:569–577CrossRef

Wahl DA, Czernuszka JT (2006) Collagen-hydroxyapatite composites for hard tissue repair. Euro Cells Mater 11:43–56

Wakeland S, Martinez R, Grey JK, Luhrs CC (2010) Production of graphene from graphite oxide using urea as expansion-reduction agent. Carbon 48:3463–3470CrossRef

White AA, Best SM, Kinloch IA (2007) Hydroxyapatite-carbon nanotube composites for biomedical applications: a review. Int J Appl Ceram Technol 4:1–13CrossRef

With GD, Van Dijk HJA, Hattu N, Prijs K (1981) Preparation, micro-structure and mechanical properties of dense polycrystalline hydroxyapatite. J Mater Sci 16:1592–1598CrossRef

Wu G, Su B, Zhang W, Wang C (2008) In vitro behaviors of hydroxyapatite reinforced polyvinyl alcohol hydrogel composite. Mater Chem Phys 107:364–369CrossRef

Yang K, Zhang S, Zhang G, Sun X, Lee ST, Liu Z (2010) Graphene in mice: Ultrahigh in vivo tumor uptake and efficient photothermal therapy. Nano Lett 10:3318–3323CrossRef

Yang XY, Wang YS, Huang X (2011) Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH sensitivity. J Mater Chem 21:3448–3454CrossRef

Yu CC, Chang JJ, Lee YH, Lin YC, Wu MH, Yang MC, Chien C-T (2013) Electrospun scaffolds composing of alginate, chitosan, collagen and hydroxyapatite for applying in bone tissue engineering. Mater Lett 93:133–136CrossRef

Zhang Q, Chen J, Feng J, Cao Y, Deng C, Zhang X (2003) Dissolution and mineralization behaviors of HA coatings. Biomaterials 24:4741–4748CrossRef

Zhang S, Xiong P, Yang X, Wang X (2011) Novel PEG functionalized graphene nanosheets: enhancement of dispersibility and thermal stability. Nanoscale 3:2169–2174CrossRef

Zhao B, Hu H, Mandal SK, Haddon RC (2005) A bone mimic based on the self-assembly of hydroxyapatite on chemically functionalized single-walled carbon nanotubes. Chem Mater 17:3235–3241CrossRef

Titel: In vitro comparative study of pure hydroxyapatite nanorods and novel polyethylene glycol/graphene oxide/hydroxyapatite nanocomposite
verfasst von: Fatemeh Mohandes
Masoud Salavati-Niasari
Publikationsdatum: 01.09.2014
Verlag: Springer Netherlands
Erschienen in: Journal of Nanoparticle Research / Ausgabe 9/2014
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-014-2604-y

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