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Quality of Life Research
Erschienen in: Quality of Life Research 4/2015

01.04.2015

Correlation of PROMIS scales and clinical measures among chronic obstructive pulmonary disease patients with and without exacerbations

verfasst von: Debra E. Irwin, Charles A. Atwood Jr., Ron D. Hays, Karen Spritzer, Honghu Liu, James F. Donohue, Nancy Kline Leidy, Susan E. Yount, Darren A. DeWalt

Erschienen in: Quality of Life Research | Ausgabe 4/2015

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Abstract

Purpose

The Patient-Reported Outcomes Measurement Information System (PROMIS®) initiative was developed to advance the methodology of PROs applicable to chronic diseases. Chronic obstructive pulmonary disease (COPD) is a progressive chronic disease associated with poor health. This study was designed to examine the correlation of PROMIS health-related quality of life (HRQOL) scales and clinical measures among COPD patients.

Methods

A cross-sectional analysis was conducted comparing patients who were stable (n = 100) with those currently experiencing a COPD exacerbation (n = 85). All PROMIS measures for adults available at the time of the study (2008), disease-targeted and other HRQOL instruments, health literacy, percent predicted FEV1, and a 6-min walk distance were assessed when patients were considered clinically stable.

Results

Stable COPD patients reported significantly (p ≤ 0.05) better health-related quality of life on PROMIS domains than patients experiencing an exacerbation. PROMIS domain scores were significantly (p ≤ 0.01) correlated with each of legacy measures. Six-min walk scores were most highly correlated with the PROMIS physical function domain scores (r = 0.53) followed by the fatigue (r = −0.26), social (r = 0.24) and to a lesser extent depression (r = −0.23), and anxiety (r = −0.22) domain scores. Percent predicted FEV1 score was significantly associated with PROMIS physical function scores (r = 0.27).

Conclusion

This study provides support for the validity of the PROMIS measures in COPD patients.
Vorheriger Artikel Nursing home adjustment scale: a psychometric study of an English version
Nächster Artikel Reliability and validity of a Chinese version of the Oral Health Impact Profile for edentulous subjects

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Metadaten
Titel
Correlation of PROMIS scales and clinical measures among chronic obstructive pulmonary disease patients with and without exacerbations
verfasst von
Debra E. Irwin
Charles A. Atwood Jr.
Ron D. Hays
Karen Spritzer
Honghu Liu
James F. Donohue
Nancy Kline Leidy
Susan E. Yount
Darren A. DeWalt
Publikationsdatum
01.04.2015
Verlag
Springer International Publishing
Erschienen in
Quality of Life Research / Ausgabe 4/2015
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-014-0818-1

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