nach oben

Medical & Biological Engineering & Computing

Erschienen in:

01.01.2009 | Original Article

Application of the fastest route algorithm in the interactive simulation of the effect of local ischemia on the ECG

verfasst von: Peter M. van Dam, Thom F. Oostendorp, Adriaan van Oosterom

Erschienen in: Medical & Biological Engineering & Computing | Ausgabe 1/2009

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

A method is described to determine the effect on the ECG of a reduced propagation velocity within an ischemic zone. The method was designed to change the activation sequence throughout the ventricles interactively, i.e. with a response time in the order of a second. The timing of ventricular ischemic activation was computed by using the fastest route algorithm, based on locally reduced values of the propagation velocities derived from a standard, normal activation sequence. The effect of these local reductions of the velocities on the total activation sequence, as well as the changes in the electrocardiogram that these produce, are presented.

Vorheriger Artikel Improved computational fronto-central sleep depth parameters show differences between apnea patients and control subjects

Nächster Artikel Method for patient-specific finite element modeling and simulation of deep brain stimulation

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 340 Zeitschriften

aus folgenden Fachgebieten:

Bauwesen + Immobilien
Business IT + Informatik
Finance + Banking
Management + Führung
Marketing + Vertrieb
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Bronson R (1982) Network analysis. In: Theory and problems of operations research. McGraw-Hill, Inc, New York, pp 169–172

Carmeliet E (1999) Cardiac ionic currents and acute ischemia: from channels to arrhythmias. Physiol Rev 79(3):917–1017

Coronel R, Casini S, Koopmann TT, Wilms-Schopman FJG, Verkerk AO, de Groot JR et al (2005) Right ventricular fibrosis and conduction delay in a patient with clinical signs of brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study. Circulation 112(18):2769–2777. doi:10.1161/CIRCULATIONAHA.105.532614 CrossRef

Demoulin JC, Kulbertus HE (1972) Histopathological examination of concept of left hemiblock. Br Heart J 34(8):807–814. doi:10.1136/hrt.34.8.807 CrossRef

Dubé B, Gulrajani RM, Lorange M, LeBlanc AR, Nasmith J, Nadeau RA (1996) A computer model incorporating anisotropic propagation. IV Simulation of regional myocardial ischemia. J Electrocardiol 29:91–103. doi:10.1016/S0022-0736(96)80118-X CrossRef

Durrer D, van Dam RT, Freud GE, Janse MJ, Meijler FL, Arzbaecher RC (1970) Total excitation of the isolated human heart. Circulation 41:899–912

Elharrar V, Zipes DP (1977) Cardiac electrophysiologic alterations during myocardial ischemia. Am J Physiol Heart Circ Physiol 233(3):H329–H345

Hooft van Huysduynen B, Swenne CA, Draaisma HHM, Antoni LL, van der Wall EE, Schalij MJ (2005) Validation of ECG indices of ventricular repolarization heterogeneity. J Cardiovasc Electrophysiol 16:1097–1103. doi:10.1111/j.1540-8167.2005.40758.x CrossRef

Huelsing DJ, Spitzer KW, Cordeiro JM, Pollard AE (1998) Conduction between isolated rabbit Purkinje and ventricular myocytes coupled by a variable resistance. Am J Physiol Heart Circ Physiol 274(4):H1163–H1173

10.

Huiskamp GJM (1998) Simulation of depolarization and repolarization in a membrane equations based model of the anisotropic ventricle. IEEE Trans Biomed Eng BME 45(7):847–855. doi:10.1109/10.686792 CrossRef

11.

Hunter PJ, Nielsen PM, Smaill BH, LeGrice IJ, Hunter IW (1992) An anatomical heart model with applications to myocardial activation and ventricular mechanic. CRC Crit Rev Biomed Eng 20:403–426

12.

Janse MJ, Wit AL (1989) Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. Physiol Rev 69(4):1049–1169

13.

Kleber AG, Janse MJ, Wilms-Schopmann FJ, Wilde AA, Coronel R (1986) Changes in conduction velocity during acute ischemia in ventricular myocardium of the isolated porcine heart. Circulation 73(1):189–198

14.

Kleber AG, Rudy Y (2004) Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias. Physiol Rev 84(2):431–488. doi:10.1152/physrev.00025.2003 CrossRef

15.

Oosthoek PW, Viragh S, Lamers WH, Moorman AF (1993) Immunohistochemical delineation of the conduction system II: the atrioventricular node and Purkinje fibers. Circ Res 73(3):482–491

16.

Potse M, Coronel R, LeBlanc AR, Vinet A (2007) The role of extracellular potassium transport in computer models of the ischemic zone. Med Biol Eng Comput 45(12):1187–1199. doi:10.1007/s11517-007-0276-9 CrossRef

17.

Potse M, Dumé B, Richer J, Vinet A, Gulrajani RM (2006) A comparison of monodomain and bidomain reaction–diffusion models for action potential propagation in the human heart. IEEE Trans Biomed Eng 53(12):2425–2435. doi:10.1109/TBME.2006.880875 CrossRef

18.

Press WH, Flannery BP, Teukolski SA, Vetterling WT (1988) Numerical recipes in C. The art of scientific computing. Cambridge University Press, CambridgeMATH

19.

Pressler ML, Münster PN, Huang XD (1995) Gap juction distribution in the heart: functional relevance in Cardiac Electrophysilogy. In: Zipes DP, Jalife J (eds) From cell to bedside. Saunders, London, pp 144–151

20.

Roberts D, Hersh L, Scher A (1979) Influence of cardiac fiber orientation on wavefront voltage, conduction velocity, and tissue resistivity in the dog. Circ Res 44:701–712

21.

Sano T, Takayama N, Shimamoto T (1959) Directional differences of conduction velocity in the cardiac ventricular syncytium studied by microelectrodes. Circ Res VII:262–267

22.

Spach MS, Dolber PC (1986) Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle. Evidence for electrical uncoupling of side-to-side fiber connections with increasing age. Circ Res 58(3):356–371

23.

Svendsen M, Oostendorp TF, Berbari E (2007) Evaluation of auto-regressive modeling procedures for the detection of abnormal intra-QRS potentials using a boundary element electrocardiogram model in computers in cardiology. In: Murray A (ed) Computers in cardiology, vol 34. Durham, NC, pp 289–292

24.

van Dam PM, van Oosterom A (2003) Atrial excitation assuming uniform propagation. J Cardiovasc Electrophysiol 14(s10):S166–S171. doi:10.1046/j.1540.8167.90307.x CrossRef

25.

van Dam PM, van Oosterom A (2005) Volume conductor effects involved in the genesis of the P wave. Europace 7:S30–S38. doi:10.1016/j.eupc.2005.03.013

26.

van Oosterom A (2001) Genesis of the T wave as based on an equivalent surface source model. J Electrocardiogr 34(Supplement 2001):217–227. doi:10.1054/jelc.2001.28896 CrossRef

27.

van Oosterom A (2002) Solidifying the solid angle. J Electrocardiol 35S:181–192. doi:10.1054/jelc.2002.37176 CrossRef

28.

van Oosterom A, Oostendorp TF (2004) ECGSIM: an interactive tool for studying the genesis of QRST waveforms. Heart 90(2):165–168. doi:10.1136/hrt.2003.014662 CrossRef

29.

van Oosterom A, van Dam PM (2005) The intra-myocardial distance function as used in the inverse computation of the timing of depolarization and repolarization. Comput Cardiol 32:567–570. doi:10.1109/CIC.2005.1588164 CrossRef

30.

Wellens HJJ, Conover MB (2006) The ECG in emergency decision making. Saunders/Elsevier, St Louis

31.

Wilson RJ (1975) Introduction to graph theory. Longman, London

Titel: Application of the fastest route algorithm in the interactive simulation of the effect of local ischemia on the ECG
verfasst von: Peter M. van Dam
Thom F. Oostendorp
Adriaan van Oosterom
Publikationsdatum: 01.01.2009
Verlag: Springer-Verlag
Erschienen in: Medical & Biological Engineering & Computing / Ausgabe 1/2009
Print ISSN: 0140-0118
Elektronische ISSN: 1741-0444
DOI: https://doi.org/10.1007/s11517-008-0391-2

Springer Professional

Abstract

Bitte loggen Sie sich ein, um Zugang zu Ihrer Lizenz zu erhalten.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Springer Professional "Technik"

Springer Professional "Wirtschaft"

Weitere Artikel der Ausgabe 1/2009

A non-contact vital sign monitoring system for ambulances using dual-frequency microwave radars

Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells

Extracellular volume measurements using bioimpedance spectroscopy-Hanai method and wrist–ankle resistance at 50 kHz

Withdrawal reflexes examined during human gait by ground reaction forces: site and gait phase dependency

Changes in editorial team and policies of MBEC in 2009

Modelling the human pharyngeal airway: validation of numerical simulations using in vitro experiments